Annotation Detail for NUDT4
Basic Information Top
| Gene Symbol: | NUDT4 ( DIPP2,DIPP2alpha,DIPP2beta,DKFZp686I1281,KIAA0487 ) |
|---|---|
| Gene Full Name: | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| Band: | 12q22 |
| Quick Links | Entrez ID:11163; OMIM: 609229; Uniprot ID:NUDT4_HUMAN; ENSEMBL ID: ENSG00000173598; HGNC ID: 8051 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.506325
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 66 / 564012 | 117 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 5 / 55556 | 89 | |
| adult | 116 / 1939121 | 59 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 6 / 94178 | 63 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 8 / 114246 | 70 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 17 / 263845 | 64 | |
| glioma | 15 / 106883 | 140 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 14 / 95842 | 146 | |
| liver tumor | 8 / 96359 | 83 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 241 / 3360307 | 71 | |
| ovarian tumor | 14 / 76682 | 182 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 3 / 102680 | 29 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 19 / 124949 | 152 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 1 / 29757 | 33 | |
| blood | 6 / 123478 | 48 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 95 / 1100989 | 86 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 3 / 16212 | 185 | |
| embryonic tissue | 12 / 215722 | 55 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 | |
| heart | 3 / 89626 | 33 | |
| intestine | 28 / 234472 | 119 | |
| kidney | 15 / 211777 | 70 | |
| larynx | 0 / 24145 | 0 | |
| liver | 13 / 207743 | 62 | |
| lung | 12 / 336974 | 35 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 12 / 107715 | 111 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 15 / 102051 | 146 | |
| pancreas | 11 / 214812 | 51 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 33 / 280825 | 117 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 3 / 20155 | 148 | |
| skin | 22 / 210574 | 104 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 2 / 96619 | 20 | |
| testis | 26 / 330442 | 78 | |
| thymus | 5 / 81131 | 61 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 12 / 52413 | 228 |  |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 13 / 51780 | 251 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 206303_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 129.65 | |
| Adipocyte | 58.25 | |
| AdrenalCortex | 37.85 | |
| Adrenalgland | 30.6 | |
| Amygdala | 36.5 | |
| Appendix | 45.7 | |
| AtrioventricularNode | 38.5 | |
| BDCA4+_DentriticCells | 50.2 | |
| Bonemarrow | 179.45 | |
| BronchialEpithelialCells | 35.2 | |
| CD105+_Endothelial | 69.9 | |
| CD14+_Monocytes | 29.85 | |
| CD19+_BCells(neg._sel.) | 46.45 | |
| CD33+_Myeloid | 40.55 | |
| CD34+ | 36.25 | |
| CD4+_Tcells | 37.95 | |
| CD56+_NKCells | 35.4 | |
| CD71+_EarlyErythroid | 641.5 | |
| CD8+_Tcells | 26.65 | |
| CardiacMyocytes | 43.65 | |
| Caudatenucleus | 30.5 | |
| Cerebellum | 26.3 | |
| CerebellumPeduncles | 65.55 | |
| CiliaryGanglion | 23.9 | |
| CingulateCortex | 35.9 | |
| Colorectaladenocarcinoma | 41.4 | |
| DorsalRootGanglion | 26.1 | |
| FetalThyroid | 34.25 | |
| Fetalbrain | 32.15 | |
| Fetalliver | 80.95 | |
| Fetallung | 29.8 | |
| GlobusPallidus | 25.25 | |
| Heart | 47.1 | |
| Hypothalamus | 30.15 | |
| Kidney | 50.65 | |
| Leukemia_chronicMyelogenousK-562 | 270.95 | |
| Leukemia_promyelocytic-HL-60 | 31.15 | |
| Leukemialymphoblastic(MOLT-4) | 31.05 | |
| Liver | 32.35 | |
| Lung | 37.45 | |
| Lymphnode | 28.55 | |
| Lymphoma_burkitts(Daudi) | 44.6 | |
| Lymphoma_burkitts(Raji) | 25.25 | |
| MedullaOblongata | 40.1 | |
| OccipitalLobe | 31.8 | |
| OlfactoryBulb | 25.65 | |
| Ovary | 40.2 | |
| Pancreas | 28.45 | |
| PancreaticIslet | 37.1 | |
| ParietalLobe | 35.55 | |
| Pituitary | 38.5 | |
| Placenta | 46.85 | |
| Pons | 38.05 | |
| PrefrontalCortex | 27.3 | |
| Prostate | 86.05 | |
| Salivarygland | 50.2 | |
| SkeletalMuscle | 42.45 | |
| Skin | 26.45 | |
| SmoothMuscle | 34.05 | |
| Spinalcord | 35.25 | |
| SubthalamicNucleus | 31.55 | |
| SuperiorCervicalGanglion | 80.65 | |
| TemporalLobe | 33 | |
| Testis | 85.9 | |
| TestisGermCell | 36.85 | |
| TestisIntersitial | 67.6 | |
| TestisLeydigCell | 81.35 | |
| TestisSeminiferousTubule | 59.2 | |
| Thalamus | 34.65 | |
| Thymus | 24.6 | |
| Thyroid | 42.6 | |
| Tongue | 33.7 | |
| Tonsil | 34.2 | |
| Trachea | 37.1 | |
| TrigeminalGanglion | 100.85 | |
| Uterus | 17.7 | |
| UterusCorpus | 31.2 | |
| WholeBlood | 33.5 | |
| Wholebrain | 30.9 | |
| colon | 35.6 | |
| pineal_day | 28.66 | |
| pineal_night | 37.28 | |
| retina | 44.1 | |
| small_intestine | 32.15 | |
- Probe name: A_24_P67946
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.18 ± 0.95 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.49 ± 0.32 | |
| Basal Part of Pons | 3.41 ± 0.51 | |
| Cerebellar Cortex | 3.73 ± 0.53 | |
| Cerebellar Nuclei | 3.7 ± 0.66 | |
| Claustrum | 4.22 ± 0.89 | |
| Epithalamus | 4.79 ± 0.54 | |
| Frontal Lobe | 4.48 ± 0.6 | |
| Globus Pallidus | 2.54 ± 0.79 | |
| Hypothalamus | 4.37 ± 0.64 | |
| Insula | 4.51 ± 0.3 | |
| Limbic Lobe | 3.95 ± 0.72 | |
| Mesencephalon | 3.95 ± 0.77 | |
| Myelencephalon | 4.01 ± 0.74 | |
| Occipital Lobe | 3.23 ± 0.85 | |
| Parietal Lobe | 4.1 ± 0.67 | |
| Pontine Tegmentum | 4.27 ± 0.81 | |
| Striatum | 2.8 ± 1.1 | |
| Subthalamus | 3.87 ± 0.71 | |
| Temporal Lobe | 4.35 ± 0.57 | |
| Thalamus | 3.67 ± 0.72 | |
| White Matter | 2.33 ± 0.25 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Nudt4 | CB | Cerebellum | 26.83 | |
| 44.59 | | |||
| Nudt4 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Nudt4 | HIP | Hippocampal region | 32 | |
| 38.54 | | |||
| Nudt4 | HPF | Hippocampal formation | 44.71 | |
| 50.07 | | |||
| Nudt4 | HY | Hypothalamus | 48.93 | |
| 47.13 | | |||
| Nudt4 | LSX | Lateral septal complex | 39.98 | |
| 42.58 | | |||
| Nudt4 | MB | Midbrain | 54.53 | |
| 59.23 | | |||
| Nudt4 | MY | Medulla | 58 | |
| 87.78 | | |||
| Nudt4 | OLF | Olfactory bulb | 65.41 | |
| 69.86 | | |||
| Nudt4 | P | Pons | 49.8 | |
| 65.38 | | |||
| Nudt4 | PAL | Pallidum | 51.53 | |
| 57.17 | | |||
| Nudt4 | RHP | Retrohippocampal region | 67.41 | |
| 67.89 | | |||
| Nudt4 | sAMY | Striatum-like amygdalar nuclei | 45.24 | |
| 42.29 | | |||
| Nudt4 | STR | Striatum | 27.6 | |
| 25.79 | | |||
| Nudt4 | STRd | Striatum dorsal region | 20.79 | |
| 19.44 | | |||
| Nudt4 | STRv | Striatum ventral region | 36.68 | |
| 29.8 | | |||
| Nudt4 | TH | Thalamus | 70.94 | |
| 77.77 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| NUDT4_HUMAN_1 | 10 | 1 | 10 | MMKFKPNQTR | PRIDE |
| NUDT4_HUMAN_2 | 9 | 2 | 10 | MKFKPNQTR | PRIDE |
| NUDT4_HUMAN_28 | 14 | 28 | 41 | SEQEDEVLLVSSSR | PRIDE |
| PAp00008439 | 15 | 129 | 143 | VLQCHKPVHAEYLEK | Peptide Atlas |