AutismKB 2.0

Annotation Detail for NUDT5


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Basic Information Top
Gene Symbol:NUDT5 ( YSA1,YSA1H,hYSAH1 )
Gene Full Name: nudix (nucleoside diphosphate linked moiety X)-type motif 5
Band: 10p14
Quick LinksEntrez ID:11164; OMIM: 609230; Uniprot ID:NUDT5_HUMAN; ENSEMBL ID: ENSG00000165609; HGNC ID: 8052
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst8 / 62319128
fetus44 / 56401278
neonate2 / 3109764
infant1 / 2362042
juvenile6 / 55556107
adult140 / 193912172
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma5 / 17475286
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma6 / 8282372
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor9 / 11936975
germ cell tumor31 / 263845117
glioma14 / 106883130
head and neck tumor29 / 136302212
kidney tumor7 / 68959101
leukemia12 / 95842125
liver tumor6 / 9635962
lung tumor17 / 103127164
lymphoma9 / 71755125
non-neoplasia4 / 9725041
normal247 / 336030773
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer13 / 102680126
retinoblastoma17 / 46356366
skin tumor40 / 124949320
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites6 / 40015149
bladder5 / 29757168
blood15 / 123478121
bone4 / 7165555
bone marrow5 / 48801102
brain76 / 110098969
cervix7 / 48171145
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus1 / 2020949
eye30 / 211054142
heart6 / 8962666
intestine11 / 23447246
kidney20 / 21177794
larynx0 / 241450 
liver23 / 207743110
lung41 / 336974121
lymph9 / 44270203
lymph node7 / 9161076
mammary gland10 / 15327165
mouth8 / 67052119
muscle4 / 10771537
nerve0 / 157680 
ovary5 / 10205148
pancreas14 / 21481265
parathyroid3 / 20539146
pharynx30 / 41328725
pituitary gland1 / 1658560
placenta29 / 280825103
prostate14 / 18934573
salivary gland0 / 201550 
skin47 / 210574223
spleen2 / 5395237
stomach7 / 9661972
testis15 / 33044245
thymus9 / 81131110
thyroid2 / 4747342
tonsil2 / 16999117
trachea2 / 5241338
umbilical cord2 / 13680146
uterus20 / 23287885
vascular7 / 51780135
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8136_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.6 ± 0.91
Basal Forebrain3.49 ± 0.55
Basal Part of Pons3.57 ± 0.66
Cerebellar Cortex3.2 ± 0.63
Cerebellar Nuclei3.5 ± 0.47
Claustrum3.91 ± 0.77
Epithalamus2.92 ± 0.44
Frontal Lobe3.35 ± 0.71
Globus Pallidus4.24 ± 0.53
Hypothalamus3.31 ± 0.42
Insula3.49 ± 1.1
Limbic Lobe3.66 ± 0.71
Mesencephalon3.41 ± 0.68
Myelencephalon3.58 ± 0.71
Occipital Lobe3.61 ± 0.68
Parietal Lobe3.49 ± 0.7
Pontine Tegmentum3.53 ± 0.63
Striatum3.91 ± 0.68
Subthalamus2.91 ± 0.53
Temporal Lobe3.44 ± 0.72
Thalamus3.51 ± 0.68
White Matter4.5 ± 0.53
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NUDT5_HUMAN_0 0 0 0 LDALVAEEHLTVDAR PRIDE
NUDT5_HUMAN_14 13 14 26 QYIISEELISEGK PRIDE
NUDT5_HUMAN_162 20 162 181 PGDGEFVEVISLPKNDLLQR PRIDE
NUDT5_HUMAN_181 15 181 195 LDALVAEEHLTVDAR PRIDE
NUDT5_HUMAN_196 9 196 204 VYSYALALK PRIDE
NUDT5_HUMAN_205 14 205 218 HANAKPFEVPFLKF PRIDE
NUDT5_HUMAN_55 15 55 69 EQTADGVAVIPVLQR PRIDE
NUDT5_HUMAN_70 11 70 80 TLHYECIVLVK PRIDE
NUDT5_HUMAN_91 21 91 111 CIEFPAGLIDDGETPEAAALR PRIDE
PAp00006400 30 82 111 QFRPPMGGYCIEFPAGLIDDGETPEAAALR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018