AutismKB 2.0

Annotation Detail for WDHD1


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Basic Information Top
Gene Symbol:WDHD1 ( AND-1,CHTF4,CTF4 )
Gene Full Name: WD repeat and HMG-box DNA binding protein 1
Band: 14q22.2-q22.3
Quick LinksEntrez ID:11169; OMIM: 608126; Uniprot ID:WDHD1_HUMAN; ENSEMBL ID: ENSG00000198554; HGNC ID: 23170
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst15 / 62319240
fetus16 / 56401228
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor21 / 26384579
glioma3 / 10688328
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor5 / 9635951
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal81 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood4 / 12347832
bone1 / 7165513
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue26 / 215722120
esophagus1 / 2020949
eye2 / 2110549
heart2 / 8962622
intestine2 / 2344728
kidney4 / 21177718
larynx0 / 241450 
liver5 / 20774324
lung2 / 3369745
lymph1 / 4427022
lymph node7 / 9161076
mammary gland2 / 15327113
mouth3 / 6705244
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta8 / 28082528
prostate1 / 1893455
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach2 / 9661920
testis18 / 33044254
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord2 / 13680146
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216228_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.75
Adipocyte7.05
AdrenalCortex9.45
Adrenalgland6.5
Amygdala6.95
Appendix9.6
AtrioventricularNode10.4
BDCA4+_DentriticCells7.1
Bonemarrow8
BronchialEpithelialCells6.95
CD105+_Endothelial8.65
CD14+_Monocytes7.7
CD19+_BCells(neg._sel.)7.4
CD33+_Myeloid8.65
CD34+8.95
CD4+_Tcells7.2
CD56+_NKCells8.1
CD71+_EarlyErythroid7
CD8+_Tcells6.15
CardiacMyocytes14.85
Caudatenucleus6.5
Cerebellum5.9
CerebellumPeduncles8.65
CiliaryGanglion6.3
CingulateCortex7.6
Colorectaladenocarcinoma7.15
DorsalRootGanglion6.45
FetalThyroid7.3
Fetalbrain6.75
Fetalliver6.4
Fetallung5.35
GlobusPallidus5.7
Heart11.3
Hypothalamus7.35
Kidney6.8
Leukemia_chronicMyelogenousK-5626.6
Leukemia_promyelocytic-HL-606.45
Leukemialymphoblastic(MOLT-4)6.1
Liver10.85
Lung7.85
Lymphnode5.85
Lymphoma_burkitts(Daudi)9.85
Lymphoma_burkitts(Raji)11.2
MedullaOblongata6.55
OccipitalLobe6.35
OlfactoryBulb5.55
Ovary5.6
Pancreas6.1
PancreaticIslet7.85
ParietalLobe8.3
Pituitary8.3
Placenta7
Pons7.15
PrefrontalCortex8.2
Prostate8.25
Salivarygland6.15
SkeletalMuscle12.15
Skin7.4
SmoothMuscle8.05
Spinalcord7.65
SubthalamicNucleus7
SuperiorCervicalGanglion10.8
TemporalLobe6.8
Testis6.15
TestisGermCell5.75
TestisIntersitial6.3
TestisLeydigCell8.1
TestisSeminiferousTubule6.25
Thalamus7.5
Thymus5.4
Thyroid8.5
Tongue8.85
Tonsil7.2
Trachea5.95
TrigeminalGanglion12.9
Uterus5.6
UterusCorpus7.7
WholeBlood7.75
Wholebrain5.55
colon7.15
pineal_day8.64
pineal_night8.52
retina8.575
small_intestine6.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10452_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.81 ± 0.53
Basal Forebrain4.77 ± 0.21
Basal Part of Pons4.65 ± 0.33
Cerebellar Cortex4.45 ± 0.49
Cerebellar Nuclei4.45 ± 0.31
Claustrum5.02 ± 0.51
Epithalamus4.44 ± 0.41
Frontal Lobe4.45 ± 0.49
Globus Pallidus4.26 ± 0.41
Hypothalamus4.27 ± 0.53
Insula4.59 ± 0.34
Limbic Lobe4.88 ± 0.53
Mesencephalon4.64 ± 0.45
Myelencephalon4.56 ± 0.49
Occipital Lobe4.94 ± 0.48
Parietal Lobe4.58 ± 0.46
Pontine Tegmentum4.54 ± 0.59
Striatum5.21 ± 0.42
Subthalamus4.73 ± 0.42
Temporal Lobe4.6 ± 0.44
Thalamus4.23 ± 0.48
White Matter4.88 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdhd1CBCerebellum4.96
6.11
Wdhd1CTXCerebral cortex4.65
3.36
Wdhd1HIPHippocampal region3.85
3.87
Wdhd1HPFHippocampal formation3.5
3.23
Wdhd1HYHypothalamus1.35
1.42
Wdhd1LSXLateral septal complex1.28
1.35
Wdhd1MBMidbrain1.83
2.01
Wdhd1MYMedulla3.31
3.96
Wdhd1OLFOlfactory bulb10.19
7.8
Wdhd1PPons2.77
3.23
Wdhd1PALPallidum1.18
1.32
Wdhd1RHPRetrohippocampal region2.45
1.95
Wdhd1sAMYStriatum-like amygdalar nuclei1.38
1.37
Wdhd1STRStriatum1.81
1.63
Wdhd1STRdStriatum dorsal region1.17
1.17
Wdhd1STRvStriatum ventral region4.29
3.08
Wdhd1THThalamus2.61
2.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00068278 14 11 24 GHDAPVLSLSFDPK Peptide Atlas
WDHD1_HUMAN_1020 11 1020 1030 TGFQMWLEENR PRIDE
WDHD1_HUMAN_1056 8 1056 1063 VLSTEERK PRIDE
WDHD1_HUMAN_1100 9 1100 1108 AKENLNLSK PRIDE
WDHD1_HUMAN_120 11 120 130 IVDVMDSSQQK PRIDE
WDHD1_HUMAN_148 14 148 161 DIFLASASCDGSVR PRIDE
WDHD1_HUMAN_162 18 162 179 VWQISDQTCAISWPLLQK PRIDE
WDHD1_HUMAN_192 9 192 200 LAWQPKSGK PRIDE
WDHD1_HUMAN_212 3 212 214 LYR PRIDE
WDHD1_HUMAN_273 15 273 287 GYAICGLAWHPTCGR PRIDE
WDHD1_HUMAN_430 16 430 445 QKPFQSGSTPLHLTHR PRIDE
WDHD1_HUMAN_732 13 732 744 SVIFHNHLDYLAK PRIDE
WDHD1_HUMAN_760 8 760 767 EQQELLMK PRIDE
WDHD1_HUMAN_768 7 768 774 MLALSCK PRIDE
WDHD1_HUMAN_890 10 890 899 STNSSDVSAK PRIDE
WDHD1_HUMAN_916 16 916 931 VSASSKEPAMSMNSAR PRIDE
WDHD1_HUMAN_922 10 922 931 EPAMSMNSAR PRIDE
WDHD1_HUMAN_932 10 932 941 STNILDNMGK PRIDE
WDHD1_HUMAN_945 7 945 951 KSTALSR PRIDE
WDHD1_HUMAN_972 10 972 981 QASAASYFQK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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