AutismKB 2.0

Annotation Detail for ADAMTS7


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Basic Information Top
Gene Symbol:ADAMTS7 ( ADAM-TS 7,ADAM-TS7,ADAMTS-7,DKFZp434H204 )
Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif, 7
Band: 15q25.1
Quick LinksEntrez ID:11173; OMIM: 605009; Uniprot ID:ATS7_HUMAN; ENSEMBL ID: ENSG00000136378; HGNC ID: 223
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal42 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye2 / 2110549
heart6 / 8962666
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach3 / 9661931
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220705_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.05
Adipocyte12.75
AdrenalCortex17.7
Adrenalgland10.65
Amygdala13
Appendix12.85
AtrioventricularNode14.7
BDCA4+_DentriticCells13.45
Bonemarrow14.15
BronchialEpithelialCells12.2
CD105+_Endothelial12.65
CD14+_Monocytes13.35
CD19+_BCells(neg._sel.)13.2
CD33+_Myeloid15.75
CD34+15.5
CD4+_Tcells13.8
CD56+_NKCells14.95
CD71+_EarlyErythroid11.8
CD8+_Tcells12.25
CardiacMyocytes17.05
Caudatenucleus11.4
Cerebellum10.2
CerebellumPeduncles14.2
CiliaryGanglion9.25
CingulateCortex12.9
Colorectaladenocarcinoma16.75
DorsalRootGanglion9.95
FetalThyroid12.15
Fetalbrain12.4
Fetalliver12.65
Fetallung10.4
GlobusPallidus9.3
Heart16.7
Hypothalamus10.95
Kidney10.9
Leukemia_chronicMyelogenousK-56211.45
Leukemia_promyelocytic-HL-6011.05
Leukemialymphoblastic(MOLT-4)10.15
Liver16.9
Lung13.5
Lymphnode11
Lymphoma_burkitts(Daudi)16
Lymphoma_burkitts(Raji)18.1
MedullaOblongata11.4
OccipitalLobe11.2
OlfactoryBulb9.75
Ovary9.65
Pancreas10.4
PancreaticIslet13.45
ParietalLobe13.35
Pituitary15.75
Placenta12.5
Pons12
PrefrontalCortex15.8
Prostate14.45
Salivarygland15.5
SkeletalMuscle16.65
Skin13.45
SmoothMuscle14.45
Spinalcord13.5
SubthalamicNucleus11.5
SuperiorCervicalGanglion14.6
TemporalLobe12.15
Testis10.95
TestisGermCell10.45
TestisIntersitial10.95
TestisLeydigCell12.5
TestisSeminiferousTubule10.9
Thalamus15.25
Thymus10
Thyroid15.45
Tongue14.35
Tonsil12.5
Trachea11
TrigeminalGanglion17.75
Uterus10.45
UterusCorpus14
WholeBlood13.6
Wholebrain10.65
colon12.6
pineal_day14.62
pineal_night14.46
retina15.3
small_intestine12.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11921_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.41 ± 1.08
Basal Forebrain1.64 ± 0.27
Basal Part of Pons1.71 ± 0.47
Cerebellar Cortex2.03 ± 0.8
Cerebellar Nuclei2.23 ± 0.69
Claustrum2.54 ± 0.8
Epithalamus1.81 ± 1.21
Frontal Lobe1.89 ± 0.81
Globus Pallidus2.11 ± 0.49
Hypothalamus1.9 ± 0.5
Insula1.39 ± 0.34
Limbic Lobe1.84 ± 0.74
Mesencephalon2.07 ± 0.73
Myelencephalon1.99 ± 0.8
Occipital Lobe1.72 ± 0.65
Parietal Lobe1.94 ± 0.87
Pontine Tegmentum1.95 ± 0.89
Striatum2.01 ± 0.81
Subthalamus2.06 ± 0.56
Temporal Lobe1.99 ± 0.77
Thalamus1.98 ± 0.79
White Matter2.42 ± 1.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adamts7CBCerebellum2.22
2.24
Adamts7CTXCerebral cortex0.8
0.98
Adamts7HIPHippocampal region0.93
1.09
Adamts7HPFHippocampal formation0.7
0.74
Adamts7HYHypothalamus0.1
0.11
Adamts7LSXLateral septal complex0.03
0
Adamts7MBMidbrain0.28
0.33
Adamts7MYMedulla0.52
0.66
Adamts7OLFOlfactory bulb2.26
2.83
Adamts7PPons0.66
0.85
Adamts7PALPallidum0.22
0.6
Adamts7RHPRetrohippocampal region0.3
0.2
Adamts7sAMYStriatum-like amygdalar nuclei0.13
0.1
Adamts7STRStriatum0.13
0.14
Adamts7STRdStriatum dorsal region0.13
0.12
Adamts7STRvStriatum ventral region0.14
0.19
Adamts7THThalamus0.2
0.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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