AutismKB 2.0

Annotation Detail for LZTS1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LZTS1 ( F37,FEZ1 )
Gene Full Name: leucine zipper, putative tumor suppressor 1
Band: 8p21.3
Quick LinksEntrez ID:11178; OMIM: 606551; Uniprot ID:LZTS1_HUMAN; ENSEMBL ID: ENSG00000061337; HGNC ID: 13861
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult28 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma5 / 10688346
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal70 / 336030720
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain36 / 110098932
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph1 / 4427022
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta6 / 28082521
prostate2 / 18934510
salivary gland0 / 201550 
skin12 / 21057456
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221722_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.85
Adipocyte3.8
AdrenalCortex4.05
Adrenalgland3.2
Amygdala4.05
Appendix3.85
AtrioventricularNode2.95
BDCA4+_DentriticCells4.15
Bonemarrow3.8
BronchialEpithelialCells3.75
CD105+_Endothelial3.85
CD14+_Monocytes4.1
CD19+_BCells(neg._sel.)4.05
CD33+_Myeloid4.9
CD34+4.8
CD4+_Tcells4.2
CD56+_NKCells4.55
CD71+_EarlyErythroid3.55
CD8+_Tcells3.7
CardiacMyocytes5
Caudatenucleus3.4
Cerebellum3.1
CerebellumPeduncles4.35
CiliaryGanglion2.7
CingulateCortex3.9
Colorectaladenocarcinoma3.8
DorsalRootGanglion2.9
FetalThyroid3.7
Fetalbrain3.85
Fetalliver3.3
Fetallung3.2
GlobusPallidus2.8
Heart4.9
Hypothalamus4.15
Kidney3.05
Leukemia_chronicMyelogenousK-5623.45
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.05
Liver5.1
Lung4.2
Lymphnode3.3
Lymphoma_burkitts(Daudi)4.9
Lymphoma_burkitts(Raji)5.35
MedullaOblongata3.5
OccipitalLobe3.45
OlfactoryBulb3
Ovary2.55
Pancreas3.05
PancreaticIslet4.05
ParietalLobe4
Pituitary4.45
Placenta3.9
Pons3.6
PrefrontalCortex4.75
Prostate4.45
Salivarygland3
SkeletalMuscle4.45
Skin2.9
SmoothMuscle4.35
Spinalcord4.05
SubthalamicNucleus3.45
SuperiorCervicalGanglion4.3
TemporalLobe3.45
Testis3.3
TestisGermCell3.15
TestisIntersitial3.2
TestisLeydigCell3.8
TestisSeminiferousTubule3.25
Thalamus3.9
Thymus3.05
Thyroid4.8
Tongue3.7
Tonsil3.7
Trachea3.2
TrigeminalGanglion3.8
Uterus3.1
UterusCorpus3.45
WholeBlood4.15
Wholebrain3.25
colon3.85
pineal_day4.78
pineal_night4.66
retina4.625
small_intestine3.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15157_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.82 ± 0.91
Basal Forebrain2.35 ± 0.53
Basal Part of Pons1.89 ± 0.38
Cerebellar Cortex1.85 ± 0.52
Cerebellar Nuclei2.5 ± 0.71
Claustrum2.94 ± 0.9
Epithalamus1.93 ± 0.86
Frontal Lobe2.21 ± 0.71
Globus Pallidus2.37 ± 0.39
Hypothalamus2.23 ± 0.69
Insula2.17 ± 0.83
Limbic Lobe2.25 ± 0.7
Mesencephalon2.55 ± 0.79
Myelencephalon2.34 ± 0.71
Occipital Lobe2.33 ± 0.76
Parietal Lobe2.36 ± 0.79
Pontine Tegmentum2.41 ± 0.79
Striatum3.19 ± 0.72
Subthalamus2.47 ± 0.73
Temporal Lobe2.2 ± 0.71
Thalamus2.15 ± 0.66
White Matter2.16 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lzts1CBCerebellum3.29
5.33
Lzts1CTXCerebral cortex53.15
43.75
Lzts1HIPHippocampal region17.78
21.11
Lzts1HPFHippocampal formation32.89
33.59
Lzts1HYHypothalamus0.9
0.86
Lzts1LSXLateral septal complex69.39
71.77
Lzts1MBMidbrain1.98
2.21
Lzts1MYMedulla5.95
8.68
Lzts1OLFOlfactory bulb43.19
39.71
Lzts1PPons8.76
11.85
Lzts1PALPallidum6.24
5.47
Lzts1RHPRetrohippocampal region60.95
53.33
Lzts1sAMYStriatum-like amygdalar nuclei13.99
11.41
Lzts1STRStriatum51.18
40.37
Lzts1STRdStriatum dorsal region58.87
45
Lzts1STRvStriatum ventral region44.59
34.63
Lzts1THThalamus1.89
2.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved