AutismKB 2.0

Annotation Detail for INMT


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Basic Information Top
Gene Symbol:INMT ( MGC125940,MGC125941 )
Gene Full Name: indolethylamine N-methyltransferase
Band: 7p14.3
Quick LinksEntrez ID:11185; OMIM: 604854; Uniprot ID:INMT_HUMAN; ENSEMBL ID: ENSG00000106125,ENSG00000241644; HGNC ID: 6069
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal61 / 336030718
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix1 / 4817120
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart4 / 8962644
intestine2 / 2344728
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate11 / 18934558
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P70961
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.06 ± 1.02
Basal Forebrain1.58 ± 0.22
Basal Part of Pons1.33 ± 0.37
Cerebellar Cortex1.44 ± 0.57
Cerebellar Nuclei1.91 ± 0.61
Claustrum2.73 ± 1.1
Epithalamus1.32 ± 0.77
Frontal Lobe1.5 ± 0.61
Globus Pallidus2.18 ± 0.25
Hypothalamus1.79 ± 0.7
Insula1.48 ± 0.46
Limbic Lobe1.67 ± 0.6
Mesencephalon1.79 ± 0.67
Myelencephalon1.69 ± 0.66
Occipital Lobe1.74 ± 0.66
Parietal Lobe1.67 ± 0.69
Pontine Tegmentum1.75 ± 0.67
Striatum1.87 ± 0.66
Subthalamus1.84 ± 0.62
Temporal Lobe1.62 ± 0.7
Thalamus1.61 ± 0.58
White Matter2.17 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
InmtCBCerebellum4
6.13
InmtCTXCerebral cortex5.15
5.35
InmtHIPHippocampal region7.75
9.41
InmtHPFHippocampal formation10.35
10.98
InmtHYHypothalamus2.1
2.73
InmtLSXLateral septal complex2.7
4.08
InmtMBMidbrain1.39
1.93
InmtMYMedulla2.58
4.83
InmtOLFOlfactory bulb5.31
5.37
InmtPPons2.1
3.75
InmtPALPallidum2.22
2.83
InmtRHPRetrohippocampal region17.49
15.4
InmtsAMYStriatum-like amygdalar nuclei4.71
3.99
InmtSTRStriatum3.94
4.07
InmtSTRdStriatum dorsal region4.74
4.72
InmtSTRvStriatum ventral region1.71
1.94
InmtTHThalamus1.56
2.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018