AutismKB 2.0

Annotation Detail for RASSF1


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Basic Information Top
Gene Symbol:RASSF1 ( 123F2,NORE2A,RASSF1A,RDA32,REH3P21 )
Gene Full Name: Ras association (RalGDS/AF-6) domain family member 1
Band: 3p21.31
Quick LinksEntrez ID:11186; OMIM: 605082; Uniprot ID:RASF1_HUMAN; ENSEMBL ID: ENSG00000068028; HGNC ID: 9882
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor5 / 11424643
esophageal tumor2 / 17290115
gastrointestinal tumor3 / 11936925
germ cell tumor5 / 26384518
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia12 / 95842125
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma6 / 7175583
non-neoplasia2 / 9725020
normal128 / 336030738
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood11 / 12347889
bone3 / 7165541
bone marrow4 / 4880181
brain31 / 110098928
cervix7 / 48171145
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus2 / 2020998
eye9 / 21105442
heart1 / 8962611
intestine9 / 23447238
kidney6 / 21177728
larynx1 / 2414541
liver5 / 20774324
lung11 / 33697432
lymph2 / 4427045
lymph node8 / 9161087
mammary gland3 / 15327119
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary5 / 10205148
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta22 / 28082578
prostate3 / 18934515
salivary gland0 / 201550 
skin5 / 21057423
spleen10 / 53952185
stomach8 / 9661982
testis10 / 33044230
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204346_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.8
Adipocyte3.35
AdrenalCortex3.35
Adrenalgland2.8
Amygdala3.4
Appendix3.3
AtrioventricularNode2.5
BDCA4+_DentriticCells51.5
Bonemarrow3.25
BronchialEpithelialCells3.35
CD105+_Endothelial17.3
CD14+_Monocytes77.15
CD19+_BCells(neg._sel.)93.7
CD33+_Myeloid49.95
CD34+92.6
CD4+_Tcells67.3
CD56+_NKCells365.5
CD71+_EarlyErythroid3.1
CD8+_Tcells179.8
CardiacMyocytes4.1
Caudatenucleus2.95
Cerebellum2.7
CerebellumPeduncles3.75
CiliaryGanglion2.25
CingulateCortex3.4
Colorectaladenocarcinoma3.35
DorsalRootGanglion2.5
FetalThyroid3.2
Fetalbrain3.35
Fetalliver2.85
Fetallung2.8
GlobusPallidus2.4
Heart4.15
Hypothalamus3.75
Kidney2.65
Leukemia_chronicMyelogenousK-5623.25
Leukemia_promyelocytic-HL-602.9
Leukemialymphoblastic(MOLT-4)2.7
Liver4.3
Lung3.9
Lymphnode3.15
Lymphoma_burkitts(Daudi)4.25
Lymphoma_burkitts(Raji)4.55
MedullaOblongata3.05
OccipitalLobe3
OlfactoryBulb2.65
Ovary2.2
Pancreas2.65
PancreaticIslet3.55
ParietalLobe3.45
Pituitary3.9
Placenta3.5
Pons3.15
PrefrontalCortex4.25
Prostate3.85
Salivarygland2.6
SkeletalMuscle3.8
Skin2.5
SmoothMuscle3.8
Spinalcord3.55
SubthalamicNucleus2.95
SuperiorCervicalGanglion3.65
TemporalLobe3
Testis3
TestisGermCell3.35
TestisIntersitial2.8
TestisLeydigCell3.3
TestisSeminiferousTubule3.05
Thalamus3.35
Thymus2.7
Thyroid4.2
Tongue3.2
Tonsil3.25
Trachea2.8
TrigeminalGanglion3.2
Uterus2.8
UterusCorpus2.95
WholeBlood3.95
Wholebrain2.95
colon3.35
pineal_day4.2
pineal_night4.08
retina4.075
small_intestine3.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P148777
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.08 ± 0.67
Basal Forebrain3.84 ± 0.51
Basal Part of Pons3.69 ± 0.46
Cerebellar Cortex4.12 ± 0.51
Cerebellar Nuclei4.14 ± 0.43
Claustrum4.52 ± 0.63
Epithalamus3.6 ± 0.57
Frontal Lobe3.82 ± 0.49
Globus Pallidus4.36 ± 0.46
Hypothalamus3.53 ± 0.38
Insula3.82 ± 0.35
Limbic Lobe3.92 ± 0.54
Mesencephalon3.83 ± 0.64
Myelencephalon3.96 ± 0.55
Occipital Lobe4 ± 0.51
Parietal Lobe3.81 ± 0.58
Pontine Tegmentum3.98 ± 0.51
Striatum4 ± 0.47
Subthalamus3.9 ± 0.24
Temporal Lobe3.86 ± 0.52
Thalamus3.91 ± 0.51
White Matter4.99 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rassf1CBCerebellum0.21
0.67
Rassf1CTXCerebral cortex0.29
0.65
Rassf1HIPHippocampal region0.37
0.82
Rassf1HPFHippocampal formation0.32
0.84
Rassf1HYHypothalamus0.48
1.28
Rassf1LSXLateral septal complex0.05
0.03
Rassf1MBMidbrain1.09
1.77
Rassf1MYMedulla0.45
0.78
Rassf1OLFOlfactory bulb0.93
1.87
Rassf1PPons1.11
2.6
Rassf1PALPallidum0.15
0.2
Rassf1RHPRetrohippocampal region0.2
1.11
Rassf1sAMYStriatum-like amygdalar nuclei1.05
1.67
Rassf1STRStriatum0.19
0.33
Rassf1STRdStriatum dorsal region0.1
0.27
Rassf1STRvStriatum ventral region0.18
0.13
Rassf1THThalamus0.18
0.49
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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