AutismKB 2.0

Annotation Detail for SUPT16H


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Basic Information Top
Gene Symbol:SUPT16H ( CDC68,FACTP140,FLJ10857,FLJ14010,FLJ34357,SPT16/CDC68 )
Gene Full Name: suppressor of Ty 16 homolog (S. cerevisiae)
Band: 14q11.2
Quick LinksEntrez ID:11198; OMIM: 605012; Uniprot ID:SP16H_HUMAN; ENSEMBL ID: ENSG00000092201; HGNC ID: 11465
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst11 / 62319176
fetus50 / 56401288
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor11 / 94178116
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor21 / 114246183
esophageal tumor3 / 17290173
gastrointestinal tumor11 / 11936992
germ cell tumor24 / 26384590
glioma3 / 10688328
head and neck tumor8 / 13630258
kidney tumor5 / 6895972
leukemia11 / 95842114
liver tumor9 / 9635993
lung tumor12 / 103127116
lymphoma16 / 71755222
non-neoplasia1 / 9725010
normal191 / 336030756
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS31 / 125680246
prostate cancer8 / 10268077
retinoblastoma9 / 46356194
skin tumor8 / 12494964
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites5 / 40015124
bladder2 / 2975767
blood11 / 12347889
bone6 / 7165583
bone marrow4 / 4880181
brain54 / 110098949
cervix5 / 48171103
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue26 / 215722120
esophagus3 / 20209148
eye21 / 21105499
heart8 / 8962689
intestine26 / 234472110
kidney11 / 21177751
larynx1 / 2414541
liver12 / 20774357
lung29 / 33697486
lymph11 / 44270248
lymph node5 / 9161054
mammary gland15 / 15327197
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx8 / 41328193
pituitary gland1 / 1658560
placenta16 / 28082556
prostate13 / 18934568
salivary gland1 / 2015549
skin13 / 21057461
spleen0 / 539520 
stomach8 / 9661982
testis22 / 33044266
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus29 / 232878124
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217815_at
Cell line Expression level Expression bar
721_B_lymphoblasts749.4
Adipocyte60.35
AdrenalCortex48.65
Adrenalgland42
Amygdala38.35
Appendix54.95
AtrioventricularNode36.6
BDCA4+_DentriticCells176.7
Bonemarrow79.3
BronchialEpithelialCells110.15
CD105+_Endothelial443.1
CD14+_Monocytes100.8
CD19+_BCells(neg._sel.)185.4
CD33+_Myeloid118.75
CD34+578.15
CD4+_Tcells210.7
CD56+_NKCells300.9
CD71+_EarlyErythroid219.05
CD8+_Tcells166
CardiacMyocytes93.45
Caudatenucleus52.1
Cerebellum61.65
CerebellumPeduncles117.85
CiliaryGanglion33.8
CingulateCortex59.6
Colorectaladenocarcinoma45.25
DorsalRootGanglion56.4
FetalThyroid51.65
Fetalbrain97.6
Fetalliver95.85
Fetallung54.95
GlobusPallidus57.9
Heart36.1
Hypothalamus95.8
Kidney26.35
Leukemia_chronicMyelogenousK-562122.1
Leukemia_promyelocytic-HL-60633.25
Leukemialymphoblastic(MOLT-4)389.45
Liver34.2
Lung23.5
Lymphnode51.3
Lymphoma_burkitts(Daudi)580.25
Lymphoma_burkitts(Raji)154.25
MedullaOblongata68.9
OccipitalLobe63.65
OlfactoryBulb68.15
Ovary58.4
Pancreas34.85
PancreaticIslet87.8
ParietalLobe74.8
Pituitary127.4
Placenta45.65
Pons74.55
PrefrontalCortex189.7
Prostate38.05
Salivarygland52.45
SkeletalMuscle83.6
Skin50.7
SmoothMuscle95.35
Spinalcord57
SubthalamicNucleus84.85
SuperiorCervicalGanglion62.2
TemporalLobe51.6
Testis54
TestisGermCell151.95
TestisIntersitial56.25
TestisLeydigCell104.1
TestisSeminiferousTubule101.25
Thalamus56.15
Thymus95.4
Thyroid49.6
Tongue33.25
Tonsil94.75
Trachea35.35
TrigeminalGanglion52.85
Uterus54.85
UterusCorpus63.65
WholeBlood93.5
Wholebrain52.6
colon44.1
pineal_day278.08
pineal_night215.02
retina56.725
small_intestine44.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P153800
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.03 ± 0.23
Basal Forebrain9.28 ± 0.07
Basal Part of Pons9.43 ± 0.12
Cerebellar Cortex9.47 ± 0.13
Cerebellar Nuclei9.21 ± 0.25
Claustrum9.2 ± 0.21
Epithalamus9.37 ± 0.17
Frontal Lobe9.25 ± 0.23
Globus Pallidus9.07 ± 0.08
Hypothalamus9.46 ± 0.18
Insula9.25 ± 0.14
Limbic Lobe9.15 ± 0.24
Mesencephalon9.27 ± 0.25
Myelencephalon9.2 ± 0.23
Occipital Lobe9.33 ± 0.18
Parietal Lobe9.33 ± 0.22
Pontine Tegmentum9.23 ± 0.17
Striatum9.02 ± 0.15
Subthalamus9.25 ± 0.34
Temporal Lobe9.2 ± 0.21
Thalamus9.25 ± 0.18
White Matter9.34 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Supt16hCBCerebellum36.45
46.03
Supt16hCTXCerebral cortex100
86.64
Supt16hHIPHippocampal region60.17
91.63
Supt16hHPFHippocampal formation67.87
84.12
Supt16hHYHypothalamus51.46
46.67
Supt16hLSXLateral septal complex58.4
45.45
Supt16hMBMidbrain57.77
58.05
Supt16hMYMedulla57
69.8
Supt16hOLFOlfactory bulb72.06
63.44
Supt16hPPons52.62
62.2
Supt16hPALPallidum58.35
60.45
Supt16hRHPRetrohippocampal region82.86
76.42
Supt16hsAMYStriatum-like amygdalar nuclei74.34
62.04
Supt16hSTRStriatum69.46
55.19
Supt16hSTRdStriatum dorsal region69.47
55.95
Supt16hSTRvStriatum ventral region70.97
51.95
Supt16hTHThalamus62.28
58.41
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004647 22 534 555 KYETVIMPVFGIATPFHIATIK Peptide Atlas
SP16H_HUMAN_2 11 2 12 AVTLDKDAYYR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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