AutismKB 2.0

Annotation Detail for POLI


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Basic Information Top
Gene Symbol:POLI ( RAD30B,RAD3OB )
Gene Full Name: polymerase (DNA directed) iota
Band: 18q21.2
Quick LinksEntrez ID:11201; OMIM: 605252; Uniprot ID:POLI_HUMAN; ENSEMBL ID: ENSG00000101751; HGNC ID: 9182
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst3 / 6231948
fetus18 / 56401231
neonate2 / 3109764
infant1 / 2362042
juvenile2 / 5555635
adult64 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal115 / 336030734
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye5 / 21105423
heart3 / 8962633
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung9 / 33697426
lymph0 / 442700 
lymph node3 / 9161032
mammary gland4 / 15327126
mouth0 / 670520 
muscle5 / 10771546
nerve2 / 15768126
ovary1 / 1020519
pancreas8 / 21481237
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta22 / 28082578
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach0 / 966190 
testis12 / 33044236
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord1 / 1368073
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219317_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte6.5
AdrenalCortex7.95
Adrenalgland5.85
Amygdala6.75
Appendix7.95
AtrioventricularNode5.95
BDCA4+_DentriticCells11.4
Bonemarrow7.05
BronchialEpithelialCells6.6
CD105+_Endothelial6.5
CD14+_Monocytes8.05
CD19+_BCells(neg._sel.)7.1
CD33+_Myeloid14.9
CD34+23.65
CD4+_Tcells25.3
CD56+_NKCells14.85
CD71+_EarlyErythroid6.25
CD8+_Tcells28.25
CardiacMyocytes10.25
Caudatenucleus6.1
Cerebellum5.35
CerebellumPeduncles7.85
CiliaryGanglion5.65
CingulateCortex6.95
Colorectaladenocarcinoma6.6
DorsalRootGanglion5.65
FetalThyroid7.1
Fetalbrain6.45
Fetalliver5.8
Fetallung5.6
GlobusPallidus5.05
Heart9.8
Hypothalamus7.35
Kidney5.85
Leukemia_chronicMyelogenousK-5626
Leukemia_promyelocytic-HL-609.15
Leukemialymphoblastic(MOLT-4)5.15
Liver9.65
Lung7.15
Lymphnode5.75
Lymphoma_burkitts(Daudi)9.15
Lymphoma_burkitts(Raji)10.1
MedullaOblongata5.85
OccipitalLobe5.9
OlfactoryBulb5.2
Ovary4.75
Pancreas5.55
PancreaticIslet8.5
ParietalLobe7.4
Pituitary7.95
Placenta6.5
Pons6.45
PrefrontalCortex8.15
Prostate7.55
Salivarygland5.55
SkeletalMuscle9
Skin5.75
SmoothMuscle7.6
Spinalcord7.05
SubthalamicNucleus6.55
SuperiorCervicalGanglion8.75
TemporalLobe6.2
Testis5.7
TestisGermCell30.25
TestisIntersitial23.8
TestisLeydigCell21.75
TestisSeminiferousTubule13.85
Thalamus6.85
Thymus4.95
Thyroid37.7
Tongue7.2
Tonsil6.55
Trachea5.45
TrigeminalGanglion7.95
Uterus19.1
UterusCorpus6.45
WholeBlood8.3
Wholebrain5.15
colon6.65
pineal_day8.86
pineal_night8.88
retina7.975
small_intestine6.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14541_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.37 ± 0.28
Basal Forebrain5.78 ± 0.13
Basal Part of Pons5.47 ± 0.29
Cerebellar Cortex5.35 ± 0.26
Cerebellar Nuclei5.82 ± 0.31
Claustrum5.55 ± 0.43
Epithalamus5.9 ± 0.25
Frontal Lobe5.58 ± 0.42
Globus Pallidus6.18 ± 0.19
Hypothalamus5.89 ± 0.26
Insula5.53 ± 0.26
Limbic Lobe5.52 ± 0.41
Mesencephalon5.57 ± 0.4
Myelencephalon5.56 ± 0.39
Occipital Lobe5.44 ± 0.3
Parietal Lobe5.5 ± 0.28
Pontine Tegmentum5.64 ± 0.38
Striatum5.57 ± 0.37
Subthalamus5.93 ± 0.15
Temporal Lobe5.57 ± 0.31
Thalamus5.61 ± 0.32
White Matter6.76 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PoliCBCerebellum2.11
2.76
PoliCTXCerebral cortex4.58
4.07
PoliHIPHippocampal region5.91
5.06
PoliHPFHippocampal formation5.68
4.5
PoliHYHypothalamus0.31
0.47
PoliLSXLateral septal complex0.19
0.22
PoliMBMidbrain1.39
1.99
PoliMYMedulla2.62
2.88
PoliOLFOlfactory bulb1.85
2.04
PoliPPons1.55
2.05
PoliPALPallidum2.17
2.99
PoliRHPRetrohippocampal region5.52
3.91
PolisAMYStriatum-like amygdalar nuclei0.64
0.47
PoliSTRStriatum0.66
0.94
PoliSTRdStriatum dorsal region0.83
1.3
PoliSTRvStriatum ventral region0.3
0.27
PoliTHThalamus0.78
0.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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