AutismKB 2.0

Annotation Detail for AKAP2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:AKAP2 ( AKAP-2,AKAPKL,DKFZp564L0716,FLJ53197,FLJ98336,PALM2,PRKA2 )
Gene Full Name: A kinase (PRKA) anchor protein 2
Band: 9q31.3
Quick LinksEntrez ID:11217; OMIM: 604582; Uniprot ID:AKAP2_HUMAN; ENSEMBL ID: ENSG00000157654,ENSG00000241978; HGNC ID: 372
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst3 / 6231948
fetus52 / 56401292
neonate9 / 31097289
infant0 / 236200 
juvenile4 / 5555671
adult160 / 193912182
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma12 / 82823144
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor20 / 26384575
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor10 / 68959145
leukemia14 / 95842146
liver tumor7 / 9635972
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia10 / 97250102
normal301 / 336030789
ovarian tumor0 / 766820 
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood19 / 123478153
bone10 / 71655139
bone marrow2 / 4880140
brain78 / 110098970
cervix0 / 481710 
connective tissue12 / 14925580
ear2 / 16212123
embryonic tissue19 / 21572288
esophagus1 / 2020949
eye8 / 21105437
heart11 / 89626122
intestine11 / 23447246
kidney18 / 21177784
larynx1 / 2414541
liver10 / 20774348
lung31 / 33697491
lymph1 / 4427022
lymph node14 / 91610152
mammary gland4 / 15327126
mouth1 / 6705214
muscle5 / 10771546
nerve3 / 15768190
ovary1 / 1020519
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta48 / 280825170
prostate4 / 18934521
salivary gland1 / 2015549
skin17 / 21057480
spleen9 / 53952166
stomach4 / 9661941
testis16 / 33044248
thymus12 / 81131147
thyroid4 / 4747384
tonsil0 / 169990 
trachea24 / 52413457
umbilical cord2 / 13680146
uterus17 / 23287872
vascular10 / 51780193
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202760_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts315.1
Adipocyte48.35
AdrenalCortex5.15
Adrenalgland4
Amygdala4.8
Appendix9.1
AtrioventricularNode3.65
BDCA4+_DentriticCells84.65
Bonemarrow4.5
BronchialEpithelialCells19.15
CD105+_Endothelial5.45
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)481.15
CD33+_Myeloid5.7
CD34+80.85
CD4+_Tcells4.95
CD56+_NKCells50
CD71+_EarlyErythroid4.3
CD8+_Tcells4.35
CardiacMyocytes14.95
Caudatenucleus3.9
Cerebellum3.65
CerebellumPeduncles5.05
CiliaryGanglion4
CingulateCortex4.75
Colorectaladenocarcinoma4.7
DorsalRootGanglion3.65
FetalThyroid6
Fetalbrain4.4
Fetalliver3.85
Fetallung61.5
GlobusPallidus3.4
Heart6.8
Hypothalamus7.55
Kidney3.8
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)52.5
Liver6.1
Lung30.2
Lymphnode14.7
Lymphoma_burkitts(Daudi)10.05
Lymphoma_burkitts(Raji)34
MedullaOblongata4.2
OccipitalLobe4.1
OlfactoryBulb6.45
Ovary3.1
Pancreas3.65
PancreaticIslet7.25
ParietalLobe4.85
Pituitary5.2
Placenta152.55
Pons4.3
PrefrontalCortex16.05
Prostate5.45
Salivarygland3.6
SkeletalMuscle5.8
Skin3.7
SmoothMuscle76.7
Spinalcord4.85
SubthalamicNucleus4.15
SuperiorCervicalGanglion5.35
TemporalLobe4.2
Testis3.75
TestisGermCell3.6
TestisIntersitial3.75
TestisLeydigCell4.5
TestisSeminiferousTubule3.8
Thalamus4.75
Thymus41.9
Thyroid14.5
Tongue4.5
Tonsil9
Trachea4.9
TrigeminalGanglion4.75
Uterus63.4
UterusCorpus4.35
WholeBlood4.8
Wholebrain3.9
colon6.5
pineal_day5.68
pineal_night13.56
retina5.525
small_intestine12.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Akap2CBCerebellum50.81
84.38
Akap2CTXCerebral cortex47.39
36.83
Akap2HIPHippocampal region59.11
53.58
Akap2HPFHippocampal formation62.02
52.35
Akap2HYHypothalamus41.34
34.51
Akap2LSXLateral septal complex17.32
13.79
Akap2MBMidbrain41.95
42.44
Akap2MYMedulla62.34
64.12
Akap2OLFOlfactory bulb63.86
44.55
Akap2PPons61.75
64.95
Akap2PALPallidum37.02
36.35
Akap2RHPRetrohippocampal region59.78
51.24
Akap2sAMYStriatum-like amygdalar nuclei53.96
44.19
Akap2STRStriatum29.21
21.01
Akap2STRdStriatum dorsal region23.74
17.03
Akap2STRvStriatum ventral region36.35
24.07
Akap2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AKAP2_HUMAN_341 21 341 361 QAPPHIELSNSSPDPMAEAER PRIDE
AKAP2_HUMAN_440 12 440 451 VRPSEEMLELEK PRIDE
AKAP2_HUMAN_560 9 560 568 QFQLMENSR PRIDE
AKAP2_HUMAN_923 19 923 941 STASLLATQESDVMVGPFK PRIDE
PAp00000467 16 312 327 AKEDIVTEQIDFSAAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved