AutismKB 2.0

Annotation Detail for RPL35


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Basic Information Top
Gene Symbol:RPL35 ( - )
Gene Full Name: ribosomal protein L35
Band: 9q33.3
Quick LinksEntrez ID:11224; OMIM: NA; Uniprot ID:RL35_HUMAN; ENSEMBL ID: ENSG00000136942; HGNC ID: 10344
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body29 / 70761409
blastocyst48 / 62319770
fetus97 / 564012171
neonate9 / 31097289
infant4 / 23620169
juvenile15 / 55556269
adult455 / 1939121234
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor11 / 12794859
bladder carcinoma1 / 1747557
breast (mammary gland) tumor28 / 94178297
cervical tumor15 / 34366436
chondrosarcoma6 / 8282372
colorectal tumor35 / 114246306
esophageal tumor1 / 1729057
gastrointestinal tumor27 / 119369226
germ cell tumor30 / 263845113
glioma25 / 106883233
head and neck tumor17 / 136302124
kidney tumor10 / 68959145
leukemia22 / 95842229
liver tumor19 / 96359197
lung tumor35 / 103127339
lymphoma18 / 71755250
non-neoplasia3 / 9725030
normal853 / 3360307253
ovarian tumor17 / 76682221
pancreatic tumor25 / 104616238
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer114 / 1026801110
retinoblastoma8 / 46356172
skin tumor39 / 124949312
soft tissue/muscle tissue tumor29 / 125191231
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland16 / 33197481
ascites5 / 40015124
bladder3 / 29757100
blood57 / 123478461
bone23 / 71655320
bone marrow29 / 48801594
brain85 / 110098977
cervix15 / 48171311
connective tissue11 / 14925573
ear2 / 16212123
embryonic tissue139 / 215722644
esophagus1 / 2020949
eye35 / 211054165
heart35 / 89626390
intestine54 / 234472230
kidney26 / 211777122
larynx6 / 24145248
liver94 / 207743452
lung69 / 336974204
lymph12 / 44270271
lymph node9 / 9161098
mammary gland29 / 153271189
mouth4 / 6705259
muscle48 / 107715445
nerve4 / 15768253
ovary28 / 102051274
pancreas30 / 214812139
parathyroid0 / 205390 
pharynx7 / 41328169
pituitary gland9 / 16585542
placenta17 / 28082560
prostate148 / 189345781
salivary gland5 / 20155248
skin47 / 210574223
spleen1 / 5395218
stomach24 / 96619248
testis18 / 33044254
thymus4 / 8113149
thyroid12 / 47473252
tonsil5 / 16999294
trachea0 / 524130 
umbilical cord9 / 13680657
uterus24 / 232878103
vascular37 / 51780714
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200002_at
Cell line Expression level Expression bar
721_B_lymphoblasts5014.3
Adipocyte1933.35
AdrenalCortex1368.7
Adrenalgland1571.85
Amygdala930.9
Appendix2100.95
AtrioventricularNode191
BDCA4+_DentriticCells3846.2
Bonemarrow1491.1
BronchialEpithelialCells5554.55
CD105+_Endothelial3373.1
CD14+_Monocytes2290.55
CD19+_BCells(neg._sel.)5386.1
CD33+_Myeloid2598.95
CD34+4665.8
CD4+_Tcells5305.55
CD56+_NKCells3337.25
CD71+_EarlyErythroid1517.25
CD8+_Tcells4686.15
CardiacMyocytes2372.7
Caudatenucleus690.9
Cerebellum756.2
CerebellumPeduncles1263.7
CiliaryGanglion156.6
CingulateCortex548.3
Colorectaladenocarcinoma4299.75
DorsalRootGanglion451.15
FetalThyroid2026.4
Fetalbrain1688.75
Fetalliver1143.5
Fetallung1970.75
GlobusPallidus157.75
Heart4122.35
Hypothalamus1441.3
Kidney830.05
Leukemia_chronicMyelogenousK-5623398.15
Leukemia_promyelocytic-HL-604372
Leukemialymphoblastic(MOLT-4)2790.25
Liver4101.6
Lung3830.95
Lymphnode2777.15
Lymphoma_burkitts(Daudi)7332.65
Lymphoma_burkitts(Raji)5956.55
MedullaOblongata634.4
OccipitalLobe700.25
OlfactoryBulb1141.7
Ovary2138.3
Pancreas2337.65
PancreaticIslet3731.95
ParietalLobe453.9
Pituitary1831.9
Placenta1122.6
Pons422.5
PrefrontalCortex1685.85
Prostate4343.75
Salivarygland2282.3
SkeletalMuscle628.5
Skin907.7
SmoothMuscle3535.5
Spinalcord1013.7
SubthalamicNucleus352.5
SuperiorCervicalGanglion163.45
TemporalLobe975.95
Testis1887.15
TestisGermCell1350.35
TestisIntersitial1033.35
TestisLeydigCell896.8
TestisSeminiferousTubule1044.7
Thalamus1010.75
Thymus3316.15
Thyroid2743.9
Tongue1376.55
Tonsil2449.9
Trachea1168.25
TrigeminalGanglion280.35
Uterus3985.15
UterusCorpus1748.7
WholeBlood3133.9
Wholebrain2191.45
colon1242.8
pineal_day1392.84
pineal_night1359.78
retina1863.7
small_intestine1611.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P112429
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.8 ± 0.18
Basal Forebrain13.88 ± 0.15
Basal Part of Pons13.37 ± 0.29
Cerebellar Cortex13.5 ± 0.2
Cerebellar Nuclei13.62 ± 0.27
Claustrum13.43 ± 0.34
Epithalamus13.43 ± 0.23
Frontal Lobe13.56 ± 0.25
Globus Pallidus14.35 ± 0.13
Hypothalamus13.81 ± 0.24
Insula13.66 ± 0.26
Limbic Lobe13.48 ± 0.28
Mesencephalon13.63 ± 0.27
Myelencephalon13.57 ± 0.27
Occipital Lobe13.33 ± 0.23
Parietal Lobe13.56 ± 0.23
Pontine Tegmentum13.67 ± 0.25
Striatum13.8 ± 0.21
Subthalamus13.53 ± 0.14
Temporal Lobe13.6 ± 0.26
Thalamus13.52 ± 0.21
White Matter14.07 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rpl35CBCerebellum12.1
14.19
Rpl35CTXCerebral cortex38.55
31.98
Rpl35HIPHippocampal region32.06
46.21
Rpl35HPFHippocampal formation32.54
39.68
Rpl35HYHypothalamus22.22
22.42
Rpl35LSXLateral septal complex15.92
14.27
Rpl35MBMidbrain14.81
16.47
Rpl35MYMedulla16.81
23.64
Rpl35OLFOlfactory bulb35.48
32.73
Rpl35PPons17.01
22.52
Rpl35PALPallidum18.97
21.87
Rpl35RHPRetrohippocampal region33.85
30.16
Rpl35sAMYStriatum-like amygdalar nuclei24.7
21.21
Rpl35STRStriatum13.07
11.79
Rpl35STRdStriatum dorsal region9.65
9.24
Rpl35STRvStriatum ventral region16.19
12.91
Rpl35THThalamus14.82
15.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00076162 13 20 32 QLDDLKVELSQLR Peptide Atlas
RL35_HUMAN_1 6 1 6 AKIKAR PRIDE
RL35_HUMAN_19 13 19 31 QLDDLKVELSQLR PRIDE
RL35_HUMAN_2 6 2 7 AKIKAR PRIDE
RL35_HUMAN_24 8 24 31 KVELSQLR PRIDE
RL35_HUMAN_56 10 56 65 VLTVINQTQK PRIDE
RL35_HUMAN_56 14 56 69 VLTVINQTQKENLR PRIDE
RL35_HUMAN_94 9 94 102 LNKHEENLK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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