AutismKB 2.0

Annotation Detail for CHN1


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Basic Information Top
Gene Symbol:CHN1 ( ARHGAP2,CHN,DURS2,RHOGAP2 )
Gene Full Name: chimerin (chimaerin) 1
Band: 2q31.1
Quick LinksEntrez ID:1123; OMIM: 118423; Uniprot ID:CHIN_HUMAN; ENSEMBL ID: ENSG00000128656; HGNC ID: 1943
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus30 / 56401253
neonate6 / 31097192
infant2 / 2362084
juvenile3 / 5555653
adult191 / 193912198
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor16 / 26384560
glioma6 / 10688356
head and neck tumor14 / 136302102
kidney tumor48 / 68959696
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor3 / 10312729
lymphoma5 / 7175569
non-neoplasia84 / 97250863
normal932 / 3360307277
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone6 / 7165583
bone marrow0 / 488010 
brain1037 / 1100989941
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye11 / 21105452
heart2 / 8962622
intestine5 / 23447221
kidney52 / 211777245
larynx1 / 2414541
liver7 / 20774333
lung18 / 33697453
lymph0 / 442700 
lymph node5 / 9161054
mammary gland0 / 1532710 
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx10 / 41328241
pituitary gland4 / 16585241
placenta16 / 28082556
prostate2 / 18934510
salivary gland4 / 20155198
skin21 / 21057499
spleen2 / 5395237
stomach1 / 9661910
testis21 / 33044263
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212624_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.85
Adipocyte6.1
AdrenalCortex5.85
Adrenalgland5.1
Amygdala4428.8
Appendix6.05
AtrioventricularNode4.65
BDCA4+_DentriticCells4.8
Bonemarrow5.9
BronchialEpithelialCells4.75
CD105+_Endothelial5.25
CD14+_Monocytes5.25
CD19+_BCells(neg._sel.)5.25
CD33+_Myeloid6.55
CD34+5.7
CD4+_Tcells6
CD56+_NKCells6.05
CD71+_EarlyErythroid5.4
CD8+_Tcells5.15
CardiacMyocytes7.45
Caudatenucleus1408.8
Cerebellum21.6
CerebellumPeduncles27.6
CiliaryGanglion4.35
CingulateCortex3146.6
Colorectaladenocarcinoma20.05
DorsalRootGanglion5.4
FetalThyroid5.35
Fetalbrain210.5
Fetalliver5.2
Fetallung31.4
GlobusPallidus2548.4
Heart7.45
Hypothalamus1016.05
Kidney4.6
Leukemia_chronicMyelogenousK-5625.45
Leukemia_promyelocytic-HL-604.9
Leukemialymphoblastic(MOLT-4)9.65
Liver7.25
Lung7.1
Lymphnode22.3
Lymphoma_burkitts(Daudi)6.75
Lymphoma_burkitts(Raji)8
MedullaOblongata3623.8
OccipitalLobe4497.3
OlfactoryBulb17.65
Ovary3.65
Pancreas4.85
PancreaticIslet16.35
ParietalLobe3240.25
Pituitary99.65
Placenta8.4
Pons2422.85
PrefrontalCortex6693.9
Prostate6.85
Salivarygland4.4
SkeletalMuscle6.65
Skin4.6
SmoothMuscle5.45
Spinalcord53.1
SubthalamicNucleus4160.45
SuperiorCervicalGanglion8.65
TemporalLobe3215.95
Testis14.55
TestisGermCell12.1
TestisIntersitial5.75
TestisLeydigCell5.95
TestisSeminiferousTubule5.25
Thalamus925.95
Thymus4.15
Thyroid9.25
Tongue5.6
Tonsil5.65
Trachea5.1
TrigeminalGanglion6.45
Uterus5.7
UterusCorpus5
WholeBlood5.2
Wholebrain1824.85
colon5.85
pineal_day30.8
pineal_night19.42
retina92.35
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P79482
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.6 ± 0.74
Basal Forebrain12.48 ± 0.51
Basal Part of Pons14.08 ± 0.33
Cerebellar Cortex12.46 ± 0.34
Cerebellar Nuclei12.52 ± 0.67
Claustrum13.38 ± 0.58
Epithalamus12.07 ± 0.45
Frontal Lobe13.46 ± 0.48
Globus Pallidus11.48 ± 1.24
Hypothalamus12.57 ± 0.51
Insula13.41 ± 0.3
Limbic Lobe13.57 ± 0.9
Mesencephalon12.66 ± 0.6
Myelencephalon12.92 ± 0.77
Occipital Lobe12.79 ± 0.86
Parietal Lobe13.47 ± 0.6
Pontine Tegmentum12.91 ± 0.4
Striatum12.53 ± 1.33
Subthalamus13.34 ± 0.26
Temporal Lobe13.54 ± 0.46
Thalamus12.67 ± 0.46
White Matter10.81 ± 0.96
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Chn1CBCerebellum34.76
99.19
Chn1CTXCerebral cortex100
100
Chn1HIPHippocampal region100
100
Chn1HPFHippocampal formation100
100
Chn1HYHypothalamus88.23
93.81
Chn1LSXLateral septal complex100
100
Chn1MBMidbrain88.89
100
Chn1MYMedulla85.95
100
Chn1OLFOlfactory bulb100
100
Chn1PPons83.4
100
Chn1PALPallidum85.66
98.58
Chn1RHPRetrohippocampal region100
100
Chn1sAMYStriatum-like amygdalar nuclei100
100
Chn1STRStriatum100
100
Chn1STRdStriatum dorsal region100
100
Chn1STRvStriatum ventral region100
100
Chn1THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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