AutismKB 2.0

Annotation Detail for CHN2


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Basic Information Top
Gene Symbol:CHN2 ( ARHGAP3,BCH,MGC138360,RHOGAP3 )
Gene Full Name: chimerin (chimaerin) 2
Band: 7p14.3
Quick LinksEntrez ID:1124; OMIM: 602857; Uniprot ID:CHIO_HUMAN; ENSEMBL ID: ENSG00000106069; HGNC ID: 1944
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus41 / 56401272
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult50 / 193912125
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult0 / 19391210 
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult0 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal213 / 336030763
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal5 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal2 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain171 / 1100989155
cervix0 / 481710 
connective tissue1 / 1492556
ear2 / 16212123
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine4 / 23447217
kidney6 / 21177728
larynx0 / 241450 
liver4 / 20774319
lung3 / 3369748
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen4 / 5395274
stomach1 / 9661910
testis14 / 33044242
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211419_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.25
Adipocyte15.9
AdrenalCortex23.35
Adrenalgland16.3
Amygdala17.25
Appendix26.3
AtrioventricularNode25.6
BDCA4+_DentriticCells13.5
Bonemarrow21.8
BronchialEpithelialCells14.5
CD105+_Endothelial15.9
CD14+_Monocytes18.1
CD19+_BCells(neg._sel.)16.45
CD33+_Myeloid19
CD34+18.05
CD4+_Tcells15.55
CD56+_NKCells17.1
CD71+_EarlyErythroid15.85
CD8+_Tcells13.8
CardiacMyocytes22
Caudatenucleus18.2
Cerebellum74.05
CerebellumPeduncles147.15
CiliaryGanglion18.05
CingulateCortex21.05
Colorectaladenocarcinoma16.35
DorsalRootGanglion19.85
FetalThyroid16.3
Fetalbrain26.85
Fetalliver16.7
Fetallung11.2
GlobusPallidus18.85
Heart40.55
Hypothalamus18.4
Kidney17.65
Leukemia_chronicMyelogenousK-56215.2
Leukemia_promyelocytic-HL-6014.6
Leukemialymphoblastic(MOLT-4)12.85
Liver29.35
Lung18.3
Lymphnode13.45
Lymphoma_burkitts(Daudi)22.3
Lymphoma_burkitts(Raji)25.55
MedullaOblongata19.3
OccipitalLobe22.05
OlfactoryBulb13.2
Ovary15.65
Pancreas18.45
PancreaticIslet19.25
ParietalLobe22.95
Pituitary19.95
Placenta15.6
Pons33
PrefrontalCortex19.5
Prostate19.3
Salivarygland15.8
SkeletalMuscle34.95
Skin21.1
SmoothMuscle17.85
Spinalcord25.15
SubthalamicNucleus21.05
SuperiorCervicalGanglion37.4
TemporalLobe24.8
Testis14
TestisGermCell12.85
TestisIntersitial16
TestisLeydigCell21.7
TestisSeminiferousTubule14.5
Thalamus20.1
Thymus11.95
Thyroid18.7
Tongue23.25
Tonsil18.15
Trachea14
TrigeminalGanglion30.3
Uterus12.35
UterusCorpus23.1
WholeBlood17.05
Wholebrain15.75
colon17.7
pineal_day618.44
pineal_night864.04
retina25.575
small_intestine27.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.93 ± 0.64
Basal Forebrain7.67 ± 0.56
Basal Part of Pons7.7 ± 0.4
Cerebellar Cortex8.66 ± 0.32
Cerebellar Nuclei8.06 ± 0.25
Claustrum8.59 ± 0.44
Epithalamus6.83 ± 0.9
Frontal Lobe7.99 ± 0.6
Globus Pallidus7.47 ± 0.38
Hypothalamus7.6 ± 0.77
Insula7.68 ± 0.29
Limbic Lobe8.1 ± 0.71
Mesencephalon7.83 ± 0.65
Myelencephalon7.92 ± 0.7
Occipital Lobe8.28 ± 0.62
Parietal Lobe8.04 ± 0.57
Pontine Tegmentum7.89 ± 0.64
Striatum6.86 ± 0.33
Subthalamus7.45 ± 0.84
Temporal Lobe7.88 ± 0.54
Thalamus7.93 ± 0.61
White Matter9.23 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Chn2CBCerebellum100
100
Chn2CTXCerebral cortex11.72
10.69
Chn2HIPHippocampal region5.55
7.17
Chn2HPFHippocampal formation5.23
7.18
Chn2HYHypothalamus5.76
6.17
Chn2LSXLateral septal complex68.07
70.08
Chn2MBMidbrain5.01
6.42
Chn2MYMedulla16.25
21.98
Chn2OLFOlfactory bulb16.9
17.27
Chn2PPons5.82
7.38
Chn2PALPallidum16.1
19
Chn2RHPRetrohippocampal region4.9
7.23
Chn2sAMYStriatum-like amygdalar nuclei13.68
14.55
Chn2STRStriatum22.06
24.72
Chn2STRdStriatum dorsal region10.73
11.87
Chn2STRvStriatum ventral region45.81
51.57
Chn2THThalamus8.9
9.99
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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