AutismKB 2.0

Annotation Detail for ZHX1


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Basic Information Top
Gene Symbol:ZHX1 ( - )
Gene Full Name: zinc fingers and homeoboxes 1
Band: 8q24.13
Quick LinksEntrez ID:11244; OMIM: 604764; Uniprot ID:ZHX1_HUMAN; ENSEMBL ID: ENSG00000165156; HGNC ID: 12871
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst0 / 623190 
fetus61 / 564012108
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult81 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor2 / 17290115
gastrointestinal tumor6 / 11936950
germ cell tumor2 / 2638457
glioma4 / 10688337
head and neck tumor10 / 13630273
kidney tumor0 / 689590 
leukemia7 / 9584273
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia12 / 97250123
normal209 / 336030762
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites4 / 4001599
bladder3 / 29757100
blood0 / 1234780 
bone0 / 716550 
bone marrow6 / 48801122
brain130 / 1100989118
cervix1 / 4817120
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus2 / 2020998
eye9 / 21105442
heart4 / 8962644
intestine3 / 23447212
kidney9 / 21177742
larynx1 / 2414541
liver5 / 20774324
lung13 / 33697438
lymph0 / 442700 
lymph node1 / 9161010
mammary gland10 / 15327165
mouth9 / 67052134
muscle7 / 10771564
nerve0 / 157680 
ovary3 / 10205129
pancreas13 / 21481260
parathyroid1 / 2053948
pharynx4 / 4132896
pituitary gland1 / 1658560
placenta6 / 28082521
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach3 / 9661931
testis11 / 33044233
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord1 / 1368073
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1326_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.49 ± 0.25
Basal Forebrain8.37 ± 0.22
Basal Part of Pons8.04 ± 0.33
Cerebellar Cortex8.24 ± 0.25
Cerebellar Nuclei8.12 ± 0.24
Claustrum8.83 ± 0.4
Epithalamus8.87 ± 0.3
Frontal Lobe8.27 ± 0.35
Globus Pallidus8.67 ± 0.21
Hypothalamus8.24 ± 0.3
Insula8.22 ± 0.26
Limbic Lobe8.37 ± 0.27
Mesencephalon8.43 ± 0.22
Myelencephalon8.34 ± 0.29
Occipital Lobe8.61 ± 0.27
Parietal Lobe8.37 ± 0.23
Pontine Tegmentum8.32 ± 0.22
Striatum8.57 ± 0.3
Subthalamus8.16 ± 0.11
Temporal Lobe8.19 ± 0.24
Thalamus8.34 ± 0.25
White Matter8.51 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zhx1CBCerebellum26.54
28.38
Zhx1CTXCerebral cortex28.3
20.83
Zhx1HIPHippocampal region49.88
77.46
Zhx1HPFHippocampal formation46.84
61.63
Zhx1HYHypothalamus33.73
27.73
Zhx1LSXLateral septal complex21.84
15.42
Zhx1MBMidbrain20.29
18.27
Zhx1MYMedulla23.42
26.01
Zhx1OLFOlfactory bulb54.39
47.87
Zhx1PPons24.9
27.72
Zhx1PALPallidum22.92
20.33
Zhx1RHPRetrohippocampal region38.29
32.35
Zhx1sAMYStriatum-like amygdalar nuclei24.39
19.45
Zhx1STRStriatum32.32
24.25
Zhx1STRdStriatum dorsal region32.56
24.06
Zhx1STRvStriatum ventral region44.99
33.85
Zhx1THThalamus25.37
20.38
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018