AutismKB 2.0

Annotation Detail for GPR176


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Basic Information Top
Gene Symbol:GPR176 ( GPR,Gm1012 )
Gene Full Name: G protein-coupled receptor 176
Band: 15q14-q15.1
Quick LinksEntrez ID:11245; OMIM: 612183; Uniprot ID:GP176_HUMAN; ENSEMBL ID: ENSG00000166073; HGNC ID: 32370
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst8 / 62319128
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor8 / 26384530
glioma4 / 10688337
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal32 / 33603079
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain14 / 110098912
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine0 / 2344720 
kidney5 / 21177723
larynx0 / 241450 
liver5 / 20774324
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary10 / 10205197
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206673_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.35
Adipocyte4.35
AdrenalCortex4.65
Adrenalgland3.65
Amygdala4.55
Appendix4.35
AtrioventricularNode5.65
BDCA4+_DentriticCells4.75
Bonemarrow4.35
BronchialEpithelialCells4.3
CD105+_Endothelial4.4
CD14+_Monocytes4.65
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid5.55
CD34+5.5
CD4+_Tcells4.65
CD56+_NKCells5.15
CD71+_EarlyErythroid4.1
CD8+_Tcells4.15
CardiacMyocytes7.1
Caudatenucleus3.9
Cerebellum3.6
CerebellumPeduncles4.95
CiliaryGanglion3.65
CingulateCortex4.45
Colorectaladenocarcinoma4.35
DorsalRootGanglion3.7
FetalThyroid4.2
Fetalbrain4.35
Fetalliver3.8
Fetallung3.55
GlobusPallidus3.25
Heart5.6
Hypothalamus4.75
Kidney3.55
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.45
Liver5.75
Lung4.75
Lymphnode3.75
Lymphoma_burkitts(Daudi)5.55
Lymphoma_burkitts(Raji)6.1
MedullaOblongata4
OccipitalLobe3.9
OlfactoryBulb3.45
Ovary2.9
Pancreas3.55
PancreaticIslet4.65
ParietalLobe4.6
Pituitary5.1
Placenta4.4
Pons4.1
PrefrontalCortex5.4
Prostate5.05
Salivarygland3.5
SkeletalMuscle5.05
Skin3.45
SmoothMuscle24.3
Spinalcord4.65
SubthalamicNucleus4
SuperiorCervicalGanglion5.1
TemporalLobe3.95
Testis3.7
TestisGermCell3.6
TestisIntersitial3.65
TestisLeydigCell4.3
TestisSeminiferousTubule3.75
Thalamus4.45
Thymus3.35
Thyroid5.45
Tongue4.75
Tonsil4.25
Trachea3.6
TrigeminalGanglion4.45
Uterus3.55
UterusCorpus3.9
WholeBlood4.65
Wholebrain3.65
colon4.4
pineal_day5.4
pineal_night5.32
retina5.25
small_intestine4.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6114_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.08 ± 0.48
Basal Forebrain5.09 ± 0.35
Basal Part of Pons4.95 ± 0.36
Cerebellar Cortex4.82 ± 0.41
Cerebellar Nuclei4.71 ± 0.64
Claustrum5.27 ± 0.56
Epithalamus4.13 ± 0.48
Frontal Lobe4.76 ± 0.44
Globus Pallidus4.24 ± 0.35
Hypothalamus4.87 ± 0.43
Insula4.58 ± 0.29
Limbic Lobe4.87 ± 0.42
Mesencephalon4.72 ± 0.53
Myelencephalon4.75 ± 0.53
Occipital Lobe4.67 ± 0.56
Parietal Lobe4.75 ± 0.44
Pontine Tegmentum4.61 ± 0.49
Striatum4.41 ± 0.53
Subthalamus4.66 ± 0.23
Temporal Lobe4.78 ± 0.51
Thalamus4.6 ± 0.55
White Matter3.82 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr176CBCerebellum2.26
4.83
Gpr176CTXCerebral cortex9.74
8
Gpr176HIPHippocampal region5.15
6.36
Gpr176HPFHippocampal formation7.36
7.7
Gpr176HYHypothalamus1.36
1.21
Gpr176LSXLateral septal complex1.15
1.11
Gpr176MBMidbrain0.76
0.92
Gpr176MYMedulla2.31
3.18
Gpr176OLFOlfactory bulb6.08
5
Gpr176PPons2.15
2.83
Gpr176PALPallidum1.03
0.86
Gpr176RHPRetrohippocampal region10.88
9.45
Gpr176sAMYStriatum-like amygdalar nuclei1.01
0.78
Gpr176STRStriatum2.37
2.09
Gpr176STRdStriatum dorsal region2.9
2.63
Gpr176STRvStriatum ventral region1.81
1.48
Gpr176THThalamus0.76
0.65
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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