AutismKB 2.0

Annotation Detail for RWDD2A


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Basic Information Top
Gene Symbol:RWDD2A ( MGC13523,MGC138208,RWDD2,dJ747H23.2 )
Gene Full Name: RWD domain containing 2A
Band: 6q14.1
Quick LinksEntrez ID:112611; OMIM: NA; Uniprot ID:RWD2A_HUMAN; ENSEMBL ID: ENSG00000013392; HGNC ID: 21385
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus19 / 56401233
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal73 / 336030721
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain34 / 110098930
cervix1 / 4817120
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine3 / 23447212
kidney5 / 21177723
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta1 / 2808253
prostate9 / 18934547
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213555_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.15
Adipocyte5.75
AdrenalCortex6.15
Adrenalgland4.95
Amygdala9.25
Appendix5.9
AtrioventricularNode4.6
BDCA4+_DentriticCells11.65
Bonemarrow5.75
BronchialEpithelialCells5.6
CD105+_Endothelial6.1
CD14+_Monocytes6.15
CD19+_BCells(neg._sel.)6.9
CD33+_Myeloid7.5
CD34+7.45
CD4+_Tcells7.65
CD56+_NKCells7.3
CD71+_EarlyErythroid5.45
CD8+_Tcells7.2
CardiacMyocytes8.15
Caudatenucleus5.15
Cerebellum4.65
CerebellumPeduncles6.65
CiliaryGanglion4.15
CingulateCortex6.1
Colorectaladenocarcinoma6
DorsalRootGanglion4.95
FetalThyroid5.7
Fetalbrain5.9
Fetalliver5
Fetallung4.55
GlobusPallidus4.5
Heart7.85
Hypothalamus9.85
Kidney4.7
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-605.05
Leukemialymphoblastic(MOLT-4)4.4
Liver7.65
Lung6.2
Lymphnode4.7
Lymphoma_burkitts(Daudi)7.4
Lymphoma_burkitts(Raji)8.15
MedullaOblongata5.5
OccipitalLobe5.3
OlfactoryBulb4.55
Ovary3.85
Pancreas4.65
PancreaticIslet6.5
ParietalLobe6.15
Pituitary6.75
Placenta5.55
Pons5.6
PrefrontalCortex14.15
Prostate7.6
Salivarygland4.75
SkeletalMuscle7.05
Skin4.5
SmoothMuscle8.95
Spinalcord6.3
SubthalamicNucleus5.5
SuperiorCervicalGanglion7
TemporalLobe5.4
Testis5
TestisGermCell20.55
TestisIntersitial12.3
TestisLeydigCell14.25
TestisSeminiferousTubule5.3
Thalamus5.95
Thymus4.25
Thyroid7.5
Tongue5.75
Tonsil5.7
Trachea4.75
TrigeminalGanglion5.95
Uterus4.75
UterusCorpus5.3
WholeBlood6.2
Wholebrain6.25
colon5.8
pineal_day7.8
pineal_night7.42
retina7.7
small_intestine5.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_464_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.31 ± 0.22
Basal Forebrain5.99 ± 0.3
Basal Part of Pons6.22 ± 0.32
Cerebellar Cortex5.97 ± 0.27
Cerebellar Nuclei5.83 ± 0.3
Claustrum6.05 ± 0.43
Epithalamus5.53 ± 0.24
Frontal Lobe6.02 ± 0.32
Globus Pallidus5.6 ± 0.38
Hypothalamus6.18 ± 0.21
Insula6.05 ± 0.26
Limbic Lobe6.19 ± 0.29
Mesencephalon5.92 ± 0.44
Myelencephalon5.95 ± 0.38
Occipital Lobe6.07 ± 0.29
Parietal Lobe6.07 ± 0.34
Pontine Tegmentum5.99 ± 0.35
Striatum5.45 ± 0.42
Subthalamus5.83 ± 0.14
Temporal Lobe6.09 ± 0.27
Thalamus5.86 ± 0.33
White Matter4.79 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rwdd2CBCerebellum6.1
6.28
Rwdd2CTXCerebral cortex5.88
5.08
Rwdd2HIPHippocampal region8.67
9.63
Rwdd2HPFHippocampal formation9.73
9.57
Rwdd2HYHypothalamus14.39
12.61
Rwdd2LSXLateral septal complex3.51
3.06
Rwdd2MBMidbrain11.56
11.66
Rwdd2MYMedulla13.38
15.41
Rwdd2OLFOlfactory bulb6.44
5.52
Rwdd2PPons11.68
13.08
Rwdd2PALPallidum8.34
8.09
Rwdd2RHPRetrohippocampal region12.11
9.85
Rwdd2sAMYStriatum-like amygdalar nuclei11.71
8.91
Rwdd2STRStriatum2.04
1.63
Rwdd2STRdStriatum dorsal region0.56
0.5
Rwdd2STRvStriatum ventral region1.86
1.3
Rwdd2THThalamus3.5
3.3
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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