AutismKB 2.0

Annotation Detail for SYNRG


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Basic Information Top
Gene Symbol:SYNRG ( AP1GBP1,FLJ34482,MGC104959,SYNG )
Gene Full Name: synergin, gamma
Band: 17q12
Quick LinksEntrez ID:11276; OMIM: 607291; Uniprot ID:SYNRG_HUMAN; ENSEMBL ID: ENSG00000006114; HGNC ID: 557
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus40 / 56401270
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor12 / 26384545
glioma3 / 10688328
head and neck tumor5 / 13630236
kidney tumor4 / 6895958
leukemia8 / 9584283
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia6 / 9725061
normal193 / 336030757
ovarian tumor4 / 7668252
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood8 / 12347864
bone1 / 7165513
bone marrow1 / 4880120
brain52 / 110098947
cervix1 / 4817120
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye17 / 21105480
heart7 / 8962678
intestine12 / 23447251
kidney21 / 21177799
larynx0 / 241450 
liver5 / 20774324
lung39 / 336974115
lymph0 / 442700 
lymph node20 / 91610218
mammary gland7 / 15327145
mouth6 / 6705289
muscle2 / 10771518
nerve1 / 1576863
ovary5 / 10205148
pancreas14 / 21481265
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta3 / 28082510
prostate4 / 18934521
salivary gland0 / 201550 
skin3 / 21057414
spleen2 / 5395237
stomach2 / 9661920
testis21 / 33044263
thymus13 / 81131160
thyroid3 / 4747363
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 64418_at
Cell line Expression level Expression bar
721_B_lymphoblasts39.55
Adipocyte16.5
AdrenalCortex20.2
Adrenalgland16.8
Amygdala19.5
Appendix20.5
AtrioventricularNode19.95
BDCA4+_DentriticCells138
Bonemarrow21.7
BronchialEpithelialCells14.95
CD105+_Endothelial49.15
CD14+_Monocytes53.9
CD19+_BCells(neg._sel.)158.95
CD33+_Myeloid49.25
CD34+104.9
CD4+_Tcells245.7
CD56+_NKCells422.2
CD71+_EarlyErythroid23.9
CD8+_Tcells294.25
CardiacMyocytes14.4
Caudatenucleus16.8
Cerebellum15.2
CerebellumPeduncles22.2
CiliaryGanglion14.45
CingulateCortex22.55
Colorectaladenocarcinoma18.35
DorsalRootGanglion17.4
FetalThyroid25.9
Fetalbrain35.5
Fetalliver14.15
Fetallung14.3
GlobusPallidus16.8
Heart17.95
Hypothalamus36.85
Kidney18.2
Leukemia_chronicMyelogenousK-56219.4
Leukemia_promyelocytic-HL-6014.75
Leukemialymphoblastic(MOLT-4)35.1
Liver24.7
Lung43.1
Lymphnode46.25
Lymphoma_burkitts(Daudi)30
Lymphoma_burkitts(Raji)19.35
MedullaOblongata18.8
OccipitalLobe19.8
OlfactoryBulb20.1
Ovary13.2
Pancreas13.65
PancreaticIslet24.5
ParietalLobe21.7
Pituitary46.7
Placenta18.25
Pons15
PrefrontalCortex42.85
Prostate40.3
Salivarygland19.55
SkeletalMuscle20.2
Skin21.6
SmoothMuscle13.05
Spinalcord31.9
SubthalamicNucleus20.05
SuperiorCervicalGanglion25.8
TemporalLobe13.95
Testis19.45
TestisGermCell17.55
TestisIntersitial18.15
TestisLeydigCell20.7
TestisSeminiferousTubule17.6
Thalamus22.5
Thymus63.4
Thyroid39.35
Tongue18.65
Tonsil33.85
Trachea17.05
TrigeminalGanglion29.2
Uterus19.35
UterusCorpus17
WholeBlood67.9
Wholebrain16.95
colon18.6
pineal_day55.24
pineal_night52.38
retina43.15
small_intestine18.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12268_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.83 ± 0.42
Basal Forebrain6.7 ± 0.28
Basal Part of Pons6.41 ± 0.37
Cerebellar Cortex6.19 ± 0.28
Cerebellar Nuclei5.7 ± 0.32
Claustrum7.1 ± 0.48
Epithalamus6.22 ± 0.37
Frontal Lobe6.37 ± 0.41
Globus Pallidus6.3 ± 0.24
Hypothalamus6.58 ± 0.36
Insula6.45 ± 0.42
Limbic Lobe6.6 ± 0.43
Mesencephalon6.63 ± 0.5
Myelencephalon6.51 ± 0.43
Occipital Lobe6.48 ± 0.35
Parietal Lobe6.48 ± 0.45
Pontine Tegmentum6.4 ± 0.48
Striatum6.91 ± 0.38
Subthalamus6.04 ± 0.19
Temporal Lobe6.46 ± 0.39
Thalamus6.67 ± 0.31
White Matter6.26 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ap1gbp1CBCerebellum6.96
9
Ap1gbp1CTXCerebral cortex5.47
3.74
Ap1gbp1HIPHippocampal region9.52
8.61
Ap1gbp1HPFHippocampal formation7.28
6.2
Ap1gbp1HYHypothalamus0.92
0.62
Ap1gbp1LSXLateral septal complex0.37
0.26
Ap1gbp1MBMidbrain1.35
1.39
Ap1gbp1MYMedulla5.92
7.3
Ap1gbp1OLFOlfactory bulb8.41
6.79
Ap1gbp1PPons2.77
2.89
Ap1gbp1PALPallidum1.39
1.22
Ap1gbp1RHPRetrohippocampal region3.55
2.77
Ap1gbp1sAMYStriatum-like amygdalar nuclei5.49
3.69
Ap1gbp1STRStriatum2.49
1.81
Ap1gbp1STRdStriatum dorsal region1.77
1.38
Ap1gbp1STRvStriatum ventral region4.02
2.52
Ap1gbp1THThalamus2.67
2.12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499177 19 544 562 ELEQTAENKPLGESFAEFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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