Annotation Detail for CHRM1
Basic Information Top
| Gene Symbol: | CHRM1 ( HM1,M1,M1R,MGC30125 ) |
|---|---|
| Gene Full Name: | cholinergic receptor, muscarinic 1 |
| Band: | 11q12.3 |
| Quick Links | Entrez ID:1128; OMIM: 118510; Uniprot ID:ACM1_HUMAN; ENSEMBL ID: ENSG00000168539; HGNC ID: 1950 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.632119
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 25 / 564012 | 44 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 18 / 1939121 | 9 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 141 / 3360307 | 41 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 9 / 125680 | 71 |  |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 135 / 1100989 | 122 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 1 / 336974 | 2 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 19 / 189345 | 100 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_10867_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.03 ± 0.73 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.52 ± 0.42 | |
| Basal Part of Pons | 4.09 ± 0.57 | |
| Cerebellar Cortex | 3.81 ± 0.67 | |
| Cerebellar Nuclei | 3.72 ± 0.72 | |
| Claustrum | 4.11 ± 0.93 | |
| Epithalamus | 3.25 ± 0.58 | |
| Frontal Lobe | 3.42 ± 0.72 | |
| Globus Pallidus | 3.74 ± 0.75 | |
| Hypothalamus | 3.15 ± 0.97 | |
| Insula | 3.3 ± 0.53 | |
| Limbic Lobe | 3.76 ± 0.7 | |
| Mesencephalon | 3.58 ± 0.76 | |
| Myelencephalon | 3.57 ± 0.71 | |
| Occipital Lobe | 3.59 ± 0.73 | |
| Parietal Lobe | 3.58 ± 0.78 | |
| Pontine Tegmentum | 3.56 ± 0.72 | |
| Striatum | 3.49 ± 0.67 | |
| Subthalamus | 4.03 ± 0.31 | |
| Temporal Lobe | 3.56 ± 0.68 | |
| Thalamus | 3.52 ± 0.66 | |
| White Matter | 3.62 ± 0.38 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Chrm1 | CB | Cerebellum | 79.4 | |
| 100 | | |||
| Chrm1 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Chrm1 | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Chrm1 | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Chrm1 | HY | Hypothalamus | 71.58 | |
| 60.46 | | |||
| Chrm1 | LSX | Lateral septal complex | 100 | |
| 94.31 | | |||
| Chrm1 | MB | Midbrain | 70.84 | |
| 67.45 | | |||
| Chrm1 | MY | Medulla | 64.24 | |
| 74.07 | | |||
| Chrm1 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Chrm1 | P | Pons | 70.86 | |
| 75.42 | | |||
| Chrm1 | PAL | Pallidum | 84.58 | |
| 93.44 | | |||
| Chrm1 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Chrm1 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Chrm1 | STR | Striatum | 100 | |
| 100 | | |||
| Chrm1 | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Chrm1 | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Chrm1 | TH | Thalamus | 73.92 | |
| 68.13 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| ACM1_HUMAN_335 | 10 | 335 | 344 | DRAGKGQKPR | PRIDE |