AutismKB 2.0

Annotation Detail for MGAT4B


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Basic Information Top
Gene Symbol:MGAT4B ( GNT-IV,GNT-IVB )
Gene Full Name: mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
Band: 5q35.3
Quick LinksEntrez ID:11282; OMIM: 604561; Uniprot ID:MGT4B_HUMAN; ENSEMBL ID: ENSG00000161013; HGNC ID: 7048
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst8 / 62319128
fetus49 / 56401286
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult216 / 1939121111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor24 / 94178254
cervical tumor7 / 34366203
chondrosarcoma26 / 82823313
colorectal tumor69 / 114246603
esophageal tumor0 / 172900 
gastrointestinal tumor23 / 119369192
germ cell tumor38 / 263845144
glioma29 / 106883271
head and neck tumor68 / 136302498
kidney tumor41 / 68959594
leukemia13 / 95842135
liver tumor11 / 96359114
lung tumor98 / 103127950
lymphoma4 / 7175555
non-neoplasia5 / 9725051
normal271 / 336030780
ovarian tumor25 / 76682326
pancreatic tumor138 / 1046161319
primitive neuroectodermal tumor of the CNS56 / 125680445
prostate cancer95 / 102680925
retinoblastoma11 / 46356237
skin tumor115 / 124949920
soft tissue/muscle tissue tumor29 / 125191231
uterine tumor66 / 90257731
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites4 / 4001599
bladder5 / 29757168
blood10 / 12347880
bone12 / 71655167
bone marrow0 / 488010 
brain120 / 1100989108
cervix8 / 48171166
connective tissue16 / 149255107
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye81 / 211054383
heart6 / 8962666
intestine89 / 234472379
kidney68 / 211777321
larynx1 / 2414541
liver16 / 20774377
lung117 / 336974347
lymph0 / 442700 
lymph node6 / 9161065
mammary gland31 / 153271202
mouth0 / 670520 
muscle10 / 10771592
nerve2 / 15768126
ovary34 / 102051333
pancreas156 / 214812726
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta27 / 28082596
prostate106 / 189345559
salivary gland62 / 201553076
skin120 / 210574569
spleen2 / 5395237
stomach22 / 96619227
testis11 / 33044233
thymus1 / 8113112
thyroid5 / 47473105
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus90 / 232878386
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220189_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts51.05
Adipocyte40.75
AdrenalCortex34.4
Adrenalgland19.3
Amygdala22.45
Appendix30.75
AtrioventricularNode17.75
BDCA4+_DentriticCells43.05
Bonemarrow16.4
BronchialEpithelialCells72.15
CD105+_Endothelial85.5
CD14+_Monocytes27.75
CD19+_BCells(neg._sel.)24.65
CD33+_Myeloid57.95
CD34+72.25
CD4+_Tcells41.2
CD56+_NKCells16.5
CD71+_EarlyErythroid41.85
CD8+_Tcells27.85
CardiacMyocytes102.15
Caudatenucleus10.7
Cerebellum14.5
CerebellumPeduncles32.6
CiliaryGanglion14.85
CingulateCortex17.55
Colorectaladenocarcinoma233.6
DorsalRootGanglion14
FetalThyroid29.35
Fetalbrain44.45
Fetalliver12.1
Fetallung24.15
GlobusPallidus11.8
Heart54.9
Hypothalamus13.15
Kidney32.3
Leukemia_chronicMyelogenousK-56245.2
Leukemia_promyelocytic-HL-6019.05
Leukemialymphoblastic(MOLT-4)12.25
Liver199
Lung110.45
Lymphnode13.35
Lymphoma_burkitts(Daudi)15.2
Lymphoma_burkitts(Raji)86.1
MedullaOblongata11.8
OccipitalLobe11.8
OlfactoryBulb12.8
Ovary7.75
Pancreas15.4
PancreaticIslet33
ParietalLobe14.95
Pituitary13.7
Placenta26
Pons17.35
PrefrontalCortex17.4
Prostate50.85
Salivarygland10.45
SkeletalMuscle15.8
Skin9.15
SmoothMuscle85.8
Spinalcord14.95
SubthalamicNucleus11.55
SuperiorCervicalGanglion27.45
TemporalLobe14.4
Testis11.25
TestisGermCell11.8
TestisIntersitial13.45
TestisLeydigCell15.5
TestisSeminiferousTubule12.85
Thalamus12.2
Thymus10.05
Thyroid104.25
Tongue12.9
Tonsil14.85
Trachea10.35
TrigeminalGanglion13.4
Uterus11.75
UterusCorpus15.5
WholeBlood24.55
Wholebrain14.15
colon103.25
pineal_day17.48
pineal_night16.88
retina28.15
small_intestine135.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P29260
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.55 ± 0.49
Basal Forebrain5.12 ± 0.2
Basal Part of Pons5.15 ± 0.33
Cerebellar Cortex5.64 ± 0.38
Cerebellar Nuclei4.97 ± 0.43
Claustrum5.78 ± 0.6
Epithalamus4.55 ± 0.26
Frontal Lobe5.27 ± 0.49
Globus Pallidus4.38 ± 0.28
Hypothalamus4.67 ± 0.34
Insula5.29 ± 0.37
Limbic Lobe5.52 ± 0.45
Mesencephalon4.88 ± 0.59
Myelencephalon5.29 ± 0.57
Occipital Lobe4.82 ± 0.41
Parietal Lobe5.05 ± 0.49
Pontine Tegmentum5.25 ± 0.57
Striatum4.62 ± 0.35
Subthalamus4.42 ± 0.43
Temporal Lobe5.41 ± 0.47
Thalamus5.14 ± 0.46
White Matter4.35 ± 0.8
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mgat4bCBCerebellum24.19
27.73
Mgat4bCTXCerebral cortex34.34
25.97
Mgat4bHIPHippocampal region30.87
44.18
Mgat4bHPFHippocampal formation27.73
32.08
Mgat4bHYHypothalamus8.25
6.32
Mgat4bLSXLateral septal complex23.33
17.59
Mgat4bMBMidbrain10.29
9.01
Mgat4bMYMedulla21.62
22.24
Mgat4bOLFOlfactory bulb27.93
21.74
Mgat4bPPons16.22
16.02
Mgat4bPALPallidum8.15
7.01
Mgat4bRHPRetrohippocampal region22.6
16.22
Mgat4bsAMYStriatum-like amygdalar nuclei6.89
4.81
Mgat4bSTRStriatum19.95
13.84
Mgat4bSTRdStriatum dorsal region21.03
14.39
Mgat4bSTRvStriatum ventral region24.44
16.87
Mgat4bTHThalamus10.73
9.26
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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