AutismKB 2.0

Annotation Detail for SLCO2B1


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Basic Information Top
Gene Symbol:SLCO2B1 ( DKFZp686E0517,KIAA0880,OATP-B,OATP2B1,OATPB,SLC21A9 )
Gene Full Name: solute carrier organic anion transporter family, member 2B1
Band: 11q13
Quick LinksEntrez ID:11309; OMIM: 604988; Uniprot ID:SO2B1_HUMAN; ENSEMBL ID: ENSG00000137491; HGNC ID: 10962
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus38 / 56401267
neonate2 / 3109764
infant1 / 2362042
juvenile2 / 5555635
adult87 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor5 / 26384518
glioma10 / 10688393
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor5 / 9635951
lung tumor0 / 1031270 
lymphoma5 / 7175569
non-neoplasia29 / 97250298
normal279 / 336030783
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain177 / 1100989160
cervix0 / 481710 
connective tissue27 / 149255180
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye7 / 21105433
heart2 / 8962622
intestine11 / 23447246
kidney8 / 21177737
larynx1 / 2414541
liver10 / 20774348
lung19 / 33697456
lymph0 / 442700 
lymph node5 / 9161054
mammary gland9 / 15327158
mouth1 / 6705214
muscle3 / 10771527
nerve1 / 1576863
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta36 / 280825128
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen7 / 53952129
stomach3 / 9661931
testis8 / 33044224
thymus6 / 8113173
thyroid2 / 4747342
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus19 / 23287881
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203472_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.8
Adipocyte3.6
AdrenalCortex3.8
Adrenalgland3.05
Amygdala3.8
Appendix3.7
AtrioventricularNode2.8
BDCA4+_DentriticCells4.1
Bonemarrow3.55
BronchialEpithelialCells3.6
CD105+_Endothelial3.7
CD14+_Monocytes3.9
CD19+_BCells(neg._sel.)4
CD33+_Myeloid4.75
CD34+4.6
CD4+_Tcells4.1
CD56+_NKCells4.4
CD71+_EarlyErythroid3.4
CD8+_Tcells3.55
CardiacMyocytes4.6
Caudatenucleus3.25
Cerebellum2.9
CerebellumPeduncles4.1
CiliaryGanglion2.55
CingulateCortex3.75
Colorectaladenocarcinoma3.65
DorsalRootGanglion2.75
FetalThyroid3.55
Fetalbrain3.55
Fetalliver3.2
Fetallung3.05
GlobusPallidus2.75
Heart4.6
Hypothalamus4
Kidney2.9
Leukemia_chronicMyelogenousK-5623.3
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.95
Liver28.9
Lung6.5
Lymphnode3.15
Lymphoma_burkitts(Daudi)4.6
Lymphoma_burkitts(Raji)5.05
MedullaOblongata3.35
OccipitalLobe3.25
OlfactoryBulb2.85
Ovary2.8
Pancreas2.9
PancreaticIslet3.9
ParietalLobe3.8
Pituitary4.85
Placenta8.2
Pons3.4
PrefrontalCortex4.65
Prostate4.3
Salivarygland2.9
SkeletalMuscle4.2
Skin2.85
SmoothMuscle4.15
Spinalcord3.9
SubthalamicNucleus3.3
SuperiorCervicalGanglion4.1
TemporalLobe3.3
Testis3.1
TestisGermCell3
TestisIntersitial3
TestisLeydigCell3.55
TestisSeminiferousTubule3.1
Thalamus3.7
Thymus2.95
Thyroid4.65
Tongue3.5
Tonsil3.55
Trachea3.05
TrigeminalGanglion3.55
Uterus3
UterusCorpus3.2
WholeBlood4
Wholebrain3.1
colon3.7
pineal_day4.56
pineal_night4.46
retina4.45
small_intestine3.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P150768
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.96 ± 0.51
Basal Forebrain7.02 ± 0.28
Basal Part of Pons7.27 ± 0.36
Cerebellar Cortex6.78 ± 0.23
Cerebellar Nuclei8.19 ± 0.32
Claustrum6.81 ± 0.39
Epithalamus7.18 ± 0.59
Frontal Lobe7.25 ± 0.42
Globus Pallidus8.55 ± 0.23
Hypothalamus7 ± 0.72
Insula7.42 ± 0.32
Limbic Lobe7.05 ± 0.56
Mesencephalon7.38 ± 0.43
Myelencephalon7.36 ± 0.49
Occipital Lobe7.43 ± 0.65
Parietal Lobe7.12 ± 0.46
Pontine Tegmentum7.31 ± 0.58
Striatum7.96 ± 0.4
Subthalamus7.87 ± 0.26
Temporal Lobe7.17 ± 0.38
Thalamus7.47 ± 0.45
White Matter7.88 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slco2b1CBCerebellum2.76
2.96
Slco2b1CTXCerebral cortex12.12
7.37
Slco2b1HIPHippocampal region9.46
7.41
Slco2b1HPFHippocampal formation10.4
7.59
Slco2b1HYHypothalamus1.25
0.84
Slco2b1LSXLateral septal complex1.73
1.07
Slco2b1MBMidbrain1.56
1.33
Slco2b1MYMedulla3.3
3.7
Slco2b1OLFOlfactory bulb12.63
8.7
Slco2b1PPons2.72
3.23
Slco2b1PALPallidum5.34
3.31
Slco2b1RHPRetrohippocampal region11.75
7.57
Slco2b1sAMYStriatum-like amygdalar nuclei13
7.75
Slco2b1STRStriatum9.17
5.58
Slco2b1STRdStriatum dorsal region9.9
6.24
Slco2b1STRvStriatum ventral region6.85
3.65
Slco2b1THThalamus2.55
2
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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