Annotation Detail for CASC4
Basic Information Top
| Gene Symbol: | CASC4 ( DKFZp459F1927,H63,MGC74708 ) |
|---|---|
| Gene Full Name: | cancer susceptibility candidate 4 |
| Band: | 15q15.3 |
| Quick Links | Entrez ID:113201; OMIM: NA; Uniprot ID:CASC4_HUMAN; ENSEMBL ID: ENSG00000166734; HGNC ID: 24892 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.512867
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 9 / 70761 | 127 |  |
| blastocyst | 3 / 62319 | 48 |  |
| fetus | 31 / 564012 | 54 | |
| neonate | 0 / 31097 | 0 | |
| infant | 2 / 23620 | 84 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 131 / 1939121 | 67 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 4 / 12794 | 312 |  |
| bladder carcinoma | 3 / 17475 | 171 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 12 / 114246 | 105 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 18 / 263845 | 68 | |
| glioma | 11 / 106883 | 102 | |
| head and neck tumor | 18 / 136302 | 132 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 10 / 97250 | 102 | |
| normal | 216 / 3360307 | 64 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 9 / 102680 | 87 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 10 / 125191 | 79 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 8 / 33197 | 240 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 5 / 29757 | 168 | |
| blood | 2 / 123478 | 16 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 4 / 48801 | 81 | |
| brain | 87 / 1100989 | 79 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 9 / 149255 | 60 | |
| ear | 2 / 16212 | 123 | |
| embryonic tissue | 15 / 215722 | 69 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 17 / 211054 | 80 | |
| heart | 2 / 89626 | 22 | |
| intestine | 15 / 234472 | 63 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 1 / 24145 | 41 | |
| liver | 4 / 207743 | 19 | |
| lung | 16 / 336974 | 47 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 12 / 91610 | 130 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 6 / 67052 | 89 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 15 / 214812 | 69 | |
| parathyroid | 4 / 20539 | 194 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 3 / 16585 | 180 | |
| placenta | 10 / 280825 | 35 | |
| prostate | 14 / 189345 | 73 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 7 / 210574 | 33 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 6 / 96619 | 62 | |
| testis | 24 / 330442 | 72 | |
| thymus | 6 / 81131 | 73 | |
| thyroid | 13 / 47473 | 273 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 12 / 52413 | 228 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 23 / 232878 | 98 | |
| vascular | 4 / 51780 | 77 | |
Microarray in - Probe name: A_24_P284213
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 10.91 ± 0.25 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 11.13 ± 0.1 | |
| Basal Part of Pons | 10.52 ± 0.15 | |
| Cerebellar Cortex | 10.72 ± 0.21 | |
| Cerebellar Nuclei | 10.63 ± 0.16 | |
| Claustrum | 10.94 ± 0.2 | |
| Epithalamus | 11.5 ± 0.3 | |
| Frontal Lobe | 10.86 ± 0.26 | |
| Globus Pallidus | 11.47 ± 0.13 | |
| Hypothalamus | 10.98 ± 0.22 | |
| Insula | 10.89 ± 0.26 | |
| Limbic Lobe | 10.91 ± 0.28 | |
| Mesencephalon | 10.92 ± 0.23 | |
| Myelencephalon | 10.93 ± 0.29 | |
| Occipital Lobe | 10.94 ± 0.23 | |
| Parietal Lobe | 10.89 ± 0.28 | |
| Pontine Tegmentum | 10.97 ± 0.21 | |
| Striatum | 10.98 ± 0.2 | |
| Subthalamus | 10.66 ± 0.17 | |
| Temporal Lobe | 10.92 ± 0.22 | |
| Thalamus | 11.03 ± 0.23 | |
| White Matter | 11.4 ± 0.26 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Casc4 | CB | Cerebellum | 24.68 | |
| 64.77 | | |||
| Casc4 | CTX | Cerebral cortex | 100 | |
| 99.08 | | |||
| Casc4 | HIP | Hippocampal region | 74.01 | |
| 100 | | |||
| Casc4 | HPF | Hippocampal formation | 83.99 | |
| 100 | | |||
| Casc4 | HY | Hypothalamus | 54.99 | |
| 45.44 | | |||
| Casc4 | LSX | Lateral septal complex | 81.49 | |
| 68.95 | | |||
| Casc4 | MB | Midbrain | 38.83 | |
| 36.11 | | |||
| Casc4 | MY | Medulla | 40.81 | |
| 47.14 | | |||
| Casc4 | OLF | Olfactory bulb | 73.24 | |
| 65.73 | | |||
| Casc4 | P | Pons | 38.36 | |
| 39.98 | | |||
| Casc4 | PAL | Pallidum | 56.02 | |
| 53.26 | | |||
| Casc4 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Casc4 | sAMY | Striatum-like amygdalar nuclei | 58.17 | |
| 46.21 | | |||
| Casc4 | STR | Striatum | 55.25 | |
| 42.36 | | |||
| Casc4 | STRd | Striatum dorsal region | 48.69 | |
| 37.4 | | |||
| Casc4 | STRv | Striatum ventral region | 68.09 | |
| 48.09 | | |||
| Casc4 | TH | Thalamus | 57.79 | |
| 53.5 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00006723 | 14 | 157 | 170 | RLEYESFQCGQQMK | Peptide Atlas |