AutismKB 2.0

Annotation Detail for SLC46A1


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Basic Information Top
Gene Symbol:SLC46A1 ( FLJ39875,HCP1,MGC9564,PCFT )
Gene Full Name: solute carrier family 46 (folate transporter), member 1
Band: 17q11.2
Quick LinksEntrez ID:113235; OMIM: 611672; Uniprot ID:PCFT_HUMAN; ENSEMBL ID: ENSG00000076351; HGNC ID: 30521
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor9 / 26384534
glioma11 / 106883102
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal85 / 336030725
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer7 / 10268068
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain43 / 110098939
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye7 / 21105433
heart1 / 8962611
intestine10 / 23447242
kidney1 / 2117774
larynx0 / 241450 
liver4 / 20774319
lung7 / 33697420
lymph0 / 442700 
lymph node1 / 9161010
mammary gland5 / 15327132
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas9 / 21481241
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate9 / 18934547
salivary gland0 / 201550 
skin5 / 21057423
spleen5 / 5395292
stomach4 / 9661941
testis2 / 3304426
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P335069
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.56 ± 0.43
Basal Forebrain6.44 ± 0.33
Basal Part of Pons6.43 ± 0.32
Cerebellar Cortex6.67 ± 0.26
Cerebellar Nuclei6.63 ± 0.32
Claustrum6.76 ± 0.47
Epithalamus6.52 ± 0.34
Frontal Lobe6.32 ± 0.39
Globus Pallidus7.15 ± 0.5
Hypothalamus5.93 ± 0.39
Insula6.35 ± 0.36
Limbic Lobe6.72 ± 0.69
Mesencephalon6.53 ± 0.41
Myelencephalon6.62 ± 0.53
Occipital Lobe7 ± 0.58
Parietal Lobe6.52 ± 0.51
Pontine Tegmentum6.57 ± 0.5
Striatum7.23 ± 0.61
Subthalamus6.48 ± 0.21
Temporal Lobe6.41 ± 0.43
Thalamus6.56 ± 0.36
White Matter7.51 ± 0.53
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D11Ertd18eCBCerebellum0
0
D11Ertd18eCTXCerebral cortex0
0
D11Ertd18eHIPHippocampal region0
0
D11Ertd18eHPFHippocampal formation0
0
D11Ertd18eHYHypothalamus0
0
D11Ertd18eLSXLateral septal complex0
0
D11Ertd18eMBMidbrain0
0
D11Ertd18eMYMedulla0
0
D11Ertd18eOLFOlfactory bulb0
0
D11Ertd18ePPons0
0
D11Ertd18ePALPallidum0
0
D11Ertd18eRHPRetrohippocampal region0
0
D11Ertd18esAMYStriatum-like amygdalar nuclei0
0
D11Ertd18eSTRStriatum0
0
D11Ertd18eSTRdStriatum dorsal region0
0
D11Ertd18eSTRvStriatum ventral region0
0
D11Ertd18eTHThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039516 10 13 22 ARPAAAVLCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018