AutismKB 2.0

Annotation Detail for DDX42


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Basic Information Top
Gene Symbol:DDX42 ( FLJ43179,RHELP,RNAHP,SF3b125 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Band: 17q23.3
Quick LinksEntrez ID:11325; OMIM: 613369; Uniprot ID:DDX42_HUMAN; ENSEMBL ID: ENSG00000198231; HGNC ID: 18676
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst19 / 62319304
fetus44 / 56401278
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult160 / 193912182
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor2 / 3436658
chondrosarcoma6 / 8282372
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor17 / 26384564
glioma7 / 10688365
head and neck tumor15 / 136302110
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor8 / 9635983
lung tumor7 / 10312767
lymphoma2 / 7175527
non-neoplasia6 / 9725061
normal247 / 336030773
ovarian tumor9 / 76682117
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer18 / 102680175
retinoblastoma4 / 4635686
skin tumor30 / 124949240
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites3 / 4001574
bladder2 / 2975767
blood3 / 12347824
bone8 / 71655111
bone marrow0 / 488010 
brain66 / 110098959
cervix2 / 4817141
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue37 / 215722171
esophagus0 / 202090 
eye13 / 21105461
heart6 / 8962666
intestine25 / 234472106
kidney7 / 21177733
larynx2 / 2414582
liver12 / 20774357
lung25 / 33697474
lymph1 / 4427022
lymph node7 / 9161076
mammary gland19 / 153271123
mouth9 / 67052134
muscle10 / 10771592
nerve0 / 157680 
ovary8 / 10205178
pancreas9 / 21481241
parathyroid3 / 20539146
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta26 / 28082592
prostate21 / 189345110
salivary gland0 / 201550 
skin45 / 210574213
spleen2 / 5395237
stomach3 / 9661931
testis20 / 33044260
thymus7 / 8113186
thyroid7 / 47473147
tonsil3 / 16999176
trachea11 / 52413209
umbilical cord0 / 136800 
uterus30 / 232878128
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201788_at
Cell line Expression level Expression bar
721_B_lymphoblasts224.2
Adipocyte91.2
AdrenalCortex82.05
Adrenalgland73.15
Amygdala110.1
Appendix114.35
AtrioventricularNode91.2
BDCA4+_DentriticCells247.65
Bonemarrow78
BronchialEpithelialCells93.15
CD105+_Endothelial177.15
CD14+_Monocytes122.45
CD19+_BCells(neg._sel.)215.15
CD33+_Myeloid194.35
CD34+386.35
CD4+_Tcells228.9
CD56+_NKCells252.2
CD71+_EarlyErythroid57.25
CD8+_Tcells236.1
CardiacMyocytes79.9
Caudatenucleus89.75
Cerebellum82.2
CerebellumPeduncles131.25
CiliaryGanglion78.85
CingulateCortex131.9
Colorectaladenocarcinoma162
DorsalRootGanglion84.65
FetalThyroid97
Fetalbrain94.65
Fetalliver56.1
Fetallung89.45
GlobusPallidus69.75
Heart36
Hypothalamus172.95
Kidney70.65
Leukemia_chronicMyelogenousK-56291.85
Leukemia_promyelocytic-HL-6075.1
Leukemialymphoblastic(MOLT-4)116.85
Liver81.05
Lung73.45
Lymphnode121.8
Lymphoma_burkitts(Daudi)151.15
Lymphoma_burkitts(Raji)68.05
MedullaOblongata107.1
OccipitalLobe102.05
OlfactoryBulb87.1
Ovary67.05
Pancreas85
PancreaticIslet112.55
ParietalLobe111
Pituitary152.05
Placenta115.95
Pons102.65
PrefrontalCortex176.75
Prostate117.6
Salivarygland81.65
SkeletalMuscle132.7
Skin56.25
SmoothMuscle102.3
Spinalcord128.35
SubthalamicNucleus111.1
SuperiorCervicalGanglion94.6
TemporalLobe84.5
Testis89.1
TestisGermCell124.35
TestisIntersitial85.05
TestisLeydigCell102.55
TestisSeminiferousTubule96.6
Thalamus132.7
Thymus78.75
Thyroid143.3
Tongue96.3
Tonsil110
Trachea79.8
TrigeminalGanglion114.35
Uterus102.8
UterusCorpus89.4
WholeBlood109
Wholebrain75.65
colon103.05
pineal_day143.62
pineal_night121.98
retina167.6
small_intestine94.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P142531
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.53 ± 0.27
Basal Forebrain7.72 ± 0.08
Basal Part of Pons7.72 ± 0.22
Cerebellar Cortex7.67 ± 0.23
Cerebellar Nuclei7.75 ± 0.22
Claustrum7.54 ± 0.33
Epithalamus7.97 ± 0.32
Frontal Lobe7.7 ± 0.25
Globus Pallidus7.97 ± 0.22
Hypothalamus7.78 ± 0.16
Insula7.73 ± 0.18
Limbic Lobe7.67 ± 0.23
Mesencephalon7.73 ± 0.21
Myelencephalon7.68 ± 0.26
Occipital Lobe7.69 ± 0.22
Parietal Lobe7.81 ± 0.23
Pontine Tegmentum7.75 ± 0.28
Striatum7.77 ± 0.26
Subthalamus7.85 ± 0.28
Temporal Lobe7.71 ± 0.22
Thalamus7.7 ± 0.24
White Matter7.81 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ddx42CBCerebellum30.19
39.14
Ddx42CTXCerebral cortex83.93
70.01
Ddx42HIPHippocampal region55.73
92.1
Ddx42HPFHippocampal formation63.6
80.05
Ddx42HYHypothalamus30.29
24.53
Ddx42LSXLateral septal complex34.21
24.49
Ddx42MBMidbrain33.84
32.32
Ddx42MYMedulla42.14
47.35
Ddx42OLFOlfactory bulb66.59
59.82
Ddx42PPons33.86
37.81
Ddx42PALPallidum28.93
27.65
Ddx42RHPRetrohippocampal region76.47
67.43
Ddx42sAMYStriatum-like amygdalar nuclei35.01
28.44
Ddx42STRStriatum47.28
36.8
Ddx42STRdStriatum dorsal region49.22
39.01
Ddx42STRvStriatum ventral region51.58
38.11
Ddx42THThalamus43.54
40.7
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004575 22 270 291 KSEYTQPTPIQCQGVPVALSGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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