AutismKB 2.0

Annotation Detail for STK38


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Basic Information Top
Gene Symbol:STK38 ( NDR,NDR1 )
Gene Full Name: serine/threonine kinase 38
Band: 6p21.31
Quick LinksEntrez ID:11329; OMIM: 606964; Uniprot ID:STK38_HUMAN; ENSEMBL ID: ENSG00000112079; HGNC ID: 17847
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst4 / 6231964
fetus37 / 56401265
neonate2 / 3109764
infant1 / 2362042
juvenile2 / 5555635
adult121 / 193912162
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor11 / 94178116
cervical tumor5 / 34366145
chondrosarcoma7 / 8282384
colorectal tumor7 / 11424661
esophageal tumor1 / 1729057
gastrointestinal tumor17 / 119369142
germ cell tumor20 / 26384575
glioma0 / 1068830 
head and neck tumor43 / 136302315
kidney tumor1 / 6895914
leukemia22 / 95842229
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal192 / 336030757
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites0 / 400150 
bladder5 / 29757168
blood27 / 123478218
bone12 / 71655167
bone marrow1 / 4880120
brain34 / 110098930
cervix5 / 48171103
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue16 / 21572274
esophagus1 / 2020949
eye7 / 21105433
heart6 / 8962666
intestine16 / 23447268
kidney16 / 21177775
larynx1 / 2414541
liver7 / 20774333
lung21 / 33697462
lymph0 / 442700 
lymph node8 / 9161087
mammary gland19 / 153271123
mouth42 / 67052626
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta9 / 28082532
prostate4 / 18934521
salivary gland0 / 201550 
skin9 / 21057442
spleen5 / 5395292
stomach18 / 96619186
testis26 / 33044278
thymus10 / 81131123
thyroid2 / 4747342
tonsil0 / 169990 
trachea11 / 52413209
umbilical cord0 / 136800 
uterus34 / 232878145
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202951_at
Cell line Expression level Expression bar
721_B_lymphoblasts61.5
Adipocyte68.05
AdrenalCortex12.1
Adrenalgland9.2
Amygdala8.7
Appendix15.05
AtrioventricularNode13.55
BDCA4+_DentriticCells264.85
Bonemarrow57.2
BronchialEpithelialCells22.85
CD105+_Endothelial55.9
CD14+_Monocytes465.15
CD19+_BCells(neg._sel.)253.5
CD33+_Myeloid492.1
CD34+183.75
CD4+_Tcells771.25
CD56+_NKCells879.45
CD71+_EarlyErythroid39.45
CD8+_Tcells737
CardiacMyocytes27.3
Caudatenucleus12.65
Cerebellum8.7
CerebellumPeduncles12.45
CiliaryGanglion10.9
CingulateCortex10.85
Colorectaladenocarcinoma14.65
DorsalRootGanglion10.5
FetalThyroid12.6
Fetalbrain20.7
Fetalliver13.6
Fetallung25.05
GlobusPallidus8.1
Heart14.8
Hypothalamus14.5
Kidney10.25
Leukemia_chronicMyelogenousK-56216.05
Leukemia_promyelocytic-HL-6017.7
Leukemialymphoblastic(MOLT-4)44.95
Liver14.7
Lung13.3
Lymphnode76.6
Lymphoma_burkitts(Daudi)80.65
Lymphoma_burkitts(Raji)25.9
MedullaOblongata13.35
OccipitalLobe10.1
OlfactoryBulb19.5
Ovary10.85
Pancreas23.6
PancreaticIslet25.15
ParietalLobe11.8
Pituitary16.55
Placenta17.1
Pons10.3
PrefrontalCortex16.9
Prostate15
Salivarygland33.75
SkeletalMuscle13.8
Skin16.7
SmoothMuscle51.85
Spinalcord14.75
SubthalamicNucleus11.55
SuperiorCervicalGanglion13.6
TemporalLobe10
Testis12.35
TestisGermCell15.3
TestisIntersitial11.3
TestisLeydigCell12.85
TestisSeminiferousTubule14
Thalamus10.75
Thymus20.45
Thyroid12.15
Tongue24.4
Tonsil22.45
Trachea16.7
TrigeminalGanglion14.45
Uterus37.15
UterusCorpus11.05
WholeBlood869.35
Wholebrain5.7
colon54.5
pineal_day24.8
pineal_night23.14
retina19.9
small_intestine32.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P390704
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.32 ± 0.83
Basal Forebrain3.12 ± 0.82
Basal Part of Pons2.65 ± 0.5
Cerebellar Cortex3.3 ± 0.6
Cerebellar Nuclei3.1 ± 0.53
Claustrum3.52 ± 0.7
Epithalamus2.9 ± 0.74
Frontal Lobe2.89 ± 0.74
Globus Pallidus3.11 ± 0.5
Hypothalamus2.68 ± 0.46
Insula2.65 ± 0.82
Limbic Lobe3.17 ± 0.68
Mesencephalon3.18 ± 0.75
Myelencephalon3.06 ± 0.66
Occipital Lobe3.1 ± 0.62
Parietal Lobe3.13 ± 0.75
Pontine Tegmentum3.09 ± 0.7
Striatum2.98 ± 0.81
Subthalamus3.19 ± 0.47
Temporal Lobe2.95 ± 0.7
Thalamus2.83 ± 0.66
White Matter3.69 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Stk38CBCerebellum0
0
Stk38CTXCerebral cortex0
0
Stk38HIPHippocampal region0
0
Stk38HPFHippocampal formation0
0
Stk38HYHypothalamus0
0
Stk38LSXLateral septal complex0
0
Stk38MBMidbrain0
0
Stk38MYMedulla0
0
Stk38OLFOlfactory bulb0
0
Stk38PPons0
0
Stk38PALPallidum0
0
Stk38RHPRetrohippocampal region0
0
Stk38sAMYStriatum-like amygdalar nuclei0
0
Stk38STRStriatum0
0
Stk38STRdStriatum dorsal region0
0
Stk38STRvStriatum ventral region0
0
Stk38THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00491298 10 84 93 LGLEDFESLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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