Annotation Detail for U2AF2
Basic Information Top
| Gene Symbol: | U2AF2 ( U2AF65 ) |
|---|---|
| Gene Full Name: | U2 small nuclear RNA auxiliary factor 2 |
| Band: | 19q13.43 |
| Quick Links | Entrez ID:11338; OMIM: 191318; Uniprot ID:U2AF2_HUMAN; ENSEMBL ID: ENSG00000063244; HGNC ID: 23156 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.528007
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 39 / 564012 | 69 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 89 / 1939121 | 45 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 7 / 114246 | 61 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 8 / 263845 | 30 | |
| glioma | 14 / 106883 | 130 | |
| head and neck tumor | 12 / 136302 | 88 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 7 / 71755 | 97 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 152 / 3360307 | 45 | |
| ovarian tumor | 8 / 76682 | 104 | |
| pancreatic tumor | 9 / 104616 | 86 | |
| primitive neuroectodermal tumor of the CNS | 5 / 125680 | 39 | |
| prostate cancer | 11 / 102680 | 107 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 12 / 125191 | 95 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 3 / 33197 | 90 | |
| ascites | 4 / 40015 | 99 | |
| bladder | 2 / 29757 | 67 | |
| blood | 2 / 123478 | 16 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 27 / 1100989 | 24 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 13 / 215722 | 60 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 28 / 211054 | 132 | |
| heart | 2 / 89626 | 22 | |
| intestine | 13 / 234472 | 55 | |
| kidney | 10 / 211777 | 47 | |
| larynx | 3 / 24145 | 124 | |
| liver | 2 / 207743 | 9 |  |
| lung | 17 / 336974 | 50 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 21 / 91610 | 229 |  |
| mammary gland | 13 / 153271 | 84 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 9 / 107715 | 83 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 8 / 102051 | 78 | |
| pancreas | 10 / 214812 | 46 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 3 / 41328 | 72 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 18 / 189345 | 95 | |
| salivary gland | 5 / 20155 | 248 | |
| skin | 7 / 210574 | 33 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 3 / 96619 | 31 | |
| testis | 5 / 330442 | 15 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218382_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 12.25 | |
| Adipocyte | 5.6 | |
| AdrenalCortex | 5.9 | |
| Adrenalgland | 4.7 | |
| Amygdala | 5.85 | |
| Appendix | 5.7 | |
| AtrioventricularNode | 4.5 | |
| BDCA4+_DentriticCells | 6.7 | |
| Bonemarrow | 5.7 | |
| BronchialEpithelialCells | 5.65 | |
| CD105+_Endothelial | 5.75 | |
| CD14+_Monocytes | 5.6 | |
| CD19+_BCells(neg._sel.) | 6.1 | |
| CD33+_Myeloid | 7.3 | |
| CD34+ | 7.1 | |
| CD4+_Tcells | 6.1 | |
| CD56+_NKCells | 6.7 | |
| CD71+_EarlyErythroid | 5.25 | |
| CD8+_Tcells | 5.5 | |
| CardiacMyocytes | 7.15 | |
| Caudatenucleus | 5 | |
| Cerebellum | 4.45 | |
| CerebellumPeduncles | 6.4 | |
| CiliaryGanglion | 4.25 | |
| CingulateCortex | 5.7 | |
| Colorectaladenocarcinoma | 5.95 | |
| DorsalRootGanglion | 4.35 | |
| FetalThyroid | 5.6 | |
| Fetalbrain | 5.7 | |
| Fetalliver | 5.05 | |
| Fetallung | 4.65 | |
| GlobusPallidus | 4.15 | |
| Heart | 8.95 | |
| Hypothalamus | 6.05 | |
| Kidney | 4.75 | |
| Leukemia_chronicMyelogenousK-562 | 5.1 | |
| Leukemia_promyelocytic-HL-60 | 5 | |
| Leukemialymphoblastic(MOLT-4) | 5.5 | |
| Liver | 7.45 | |
| Lung | 6.3 | |
| Lymphnode | 5.3 | |
| Lymphoma_burkitts(Daudi) | 7.2 | |
| Lymphoma_burkitts(Raji) | 8.4 | |
| MedullaOblongata | 5.15 | |
| OccipitalLobe | 4.95 | |
| OlfactoryBulb | 4.3 | |
| Ovary | 3.75 | |
| Pancreas | 4.55 | |
| PancreaticIslet | 6 | |
| ParietalLobe | 5.8 | |
| Pituitary | 11.75 | |
| Placenta | 5.9 | |
| Pons | 5.35 | |
| PrefrontalCortex | 7.1 | |
| Prostate | 6.7 | |
| Salivarygland | 4.5 | |
| SkeletalMuscle | 6.6 | |
| Skin | 4.4 | |
| SmoothMuscle | 6.1 | |
| Spinalcord | 5.9 | |
| SubthalamicNucleus | 5.15 | |
| SuperiorCervicalGanglion | 6.9 | |
| TemporalLobe | 5.15 | |
| Testis | 4.8 | |
| TestisGermCell | 4.7 | |
| TestisIntersitial | 4.9 | |
| TestisLeydigCell | 5.55 | |
| TestisSeminiferousTubule | 5.1 | |
| Thalamus | 5.65 | |
| Thymus | 5.65 | |
| Thyroid | 7.1 | |
| Tongue | 5.55 | |
| Tonsil | 5.55 | |
| Trachea | 4.75 | |
| TrigeminalGanglion | 5.9 | |
| Uterus | 4.7 | |
| UterusCorpus | 5.35 | |
| WholeBlood | 6.35 | |
| Wholebrain | 6.1 | |
| colon | 5.7 | |
| pineal_day | 6.94 | |
| pineal_night | 6.68 | |
| retina | 6.525 | |
| small_intestine | 5.5 | |
- Probe name: CUST_13852_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.76 ± 0.74 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.3 ± 0.3 | |
| Basal Part of Pons | 3.34 ± 0.28 | |
| Cerebellar Cortex | 4.04 ± 0.49 | |
| Cerebellar Nuclei | 3.47 ± 0.52 | |
| Claustrum | 3.62 ± 0.62 | |
| Epithalamus | 3.83 ± 0.42 | |
| Frontal Lobe | 3.75 ± 0.49 | |
| Globus Pallidus | 3.62 ± 0.57 | |
| Hypothalamus | 3.74 ± 0.75 | |
| Insula | 3.9 ± 0.37 | |
| Limbic Lobe | 3.69 ± 0.56 | |
| Mesencephalon | 3.71 ± 0.57 | |
| Myelencephalon | 3.74 ± 0.59 | |
| Occipital Lobe | 3.5 ± 0.62 | |
| Parietal Lobe | 3.74 ± 0.55 | |
| Pontine Tegmentum | 3.78 ± 0.53 | |
| Striatum | 3.75 ± 0.5 | |
| Subthalamus | 3.63 ± 0.81 | |
| Temporal Lobe | 3.79 ± 0.52 | |
| Thalamus | 3.64 ± 0.53 | |
| White Matter | 4.26 ± 0.26 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| U2af2 | CB | Cerebellum | 8.9 | |
| 11.99 | | |||
| U2af2 | CTX | Cerebral cortex | 57.48 | |
| 50.7 | | |||
| U2af2 | HIP | Hippocampal region | 64.37 | |
| 100 | | |||
| U2af2 | HPF | Hippocampal formation | 55.51 | |
| 79.74 | | |||
| U2af2 | HY | Hypothalamus | 4.05 | |
| 3.69 | | |||
| U2af2 | LSX | Lateral septal complex | 2.02 | |
| 2.05 | | |||
| U2af2 | MB | Midbrain | 8.03 | |
| 9.43 | | |||
| U2af2 | MY | Medulla | 2.84 | |
| 3.99 | | |||
| U2af2 | OLF | Olfactory bulb | 30.31 | |
| 29.04 | | |||
| U2af2 | P | Pons | 2.13 | |
| 3.24 | | |||
| U2af2 | PAL | Pallidum | 9.48 | |
| 8.95 | | |||
| U2af2 | RHP | Retrohippocampal region | 36.46 | |
| 32.68 | | |||
| U2af2 | sAMY | Striatum-like amygdalar nuclei | 23.93 | |
| 17.97 | | |||
| U2af2 | STR | Striatum | 18.02 | |
| 14.1 | | |||
| U2af2 | STRd | Striatum dorsal region | 18.14 | |
| 14.45 | | |||
| U2af2 | STRv | Striatum ventral region | 21.66 | |
| 16.02 | | |||
| U2af2 | TH | Thalamus | 14.16 | |
| 14.91 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00003786 | 13 | 432 | 444 | IFVEFTSVFDCQK | Peptide Atlas |
| U2AF2_HUMAN_1 | 8 | 1 | 8 | SDFDEFER | PRIDE |
| U2AF2_HUMAN_10 | 9 | 10 | 18 | QLNENKQER | PRIDE |
| U2AF2_HUMAN_129 | 18 | 129 | 146 | GLAVTPTPVPVVGSQMTR | PRIDE |
| U2AF2_HUMAN_2 | 8 | 2 | 9 | SDFDEFER | PRIDE |
| U2AF2_HUMAN_260 | 26 | 260 | 285 | LFIGGLPNYLNDDQVKELLTSFGPLK | PRIDE |