Annotation Detail for HELQ
Basic Information Top
| Gene Symbol: | HELQ ( HEL308,MGC20604 ) |
|---|---|
| Gene Full Name: | helicase, POLQ-like |
| Band: | 4q21.23 |
| Quick Links | Entrez ID:113510; OMIM: 606769; Uniprot ID:HELQ_HUMAN; ENSEMBL ID: ENSG00000163312; HGNC ID: 18536 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.480101
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 16 / 564012 | 28 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 18 / 1939121 | 9 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 65 / 3360307 | 19 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 3 / 123478 | 24 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 10 / 1100989 | 9 | |
| cervix | 3 / 48171 | 62 |  |
| connective tissue | 4 / 149255 | 26 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 1 / 211054 | 4 | |
| heart | 1 / 89626 | 11 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 3 / 336974 | 8 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 0 / 96619 | 0 | |
| testis | 6 / 330442 | 18 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 6 / 52413 | 114 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 15 / 232878 | 64 | |
| vascular | 6 / 51780 | 115 | |
Microarray in - Probe name: A_24_P273635
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.27 ± 0.46 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.15 ± 0.51 | |
| Basal Part of Pons | 4.41 ± 0.4 | |
| Cerebellar Cortex | 4.45 ± 0.31 | |
| Cerebellar Nuclei | 4.31 ± 0.44 | |
| Claustrum | 3.93 ± 0.65 | |
| Epithalamus | 4.47 ± 0.32 | |
| Frontal Lobe | 4.12 ± 0.45 | |
| Globus Pallidus | 4.15 ± 0.54 | |
| Hypothalamus | 4.31 ± 0.54 | |
| Insula | 4.28 ± 0.34 | |
| Limbic Lobe | 4.08 ± 0.48 | |
| Mesencephalon | 4.12 ± 0.47 | |
| Myelencephalon | 4.1 ± 0.46 | |
| Occipital Lobe | 4.47 ± 0.43 | |
| Parietal Lobe | 4.18 ± 0.51 | |
| Pontine Tegmentum | 4.2 ± 0.49 | |
| Striatum | 3.98 ± 0.41 | |
| Subthalamus | 4.19 ± 0.48 | |
| Temporal Lobe | 4.1 ± 0.45 | |
| Thalamus | 4.11 ± 0.51 | |
| White Matter | 4.62 ± 0.34 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Hel308 | CB | Cerebellum | 2.31 | |
| 2.63 | | |||
| Hel308 | CTX | Cerebral cortex | 2.45 | |
| 1.64 | | |||
| Hel308 | HIP | Hippocampal region | 2.88 | |
| 2.48 | | |||
| Hel308 | HPF | Hippocampal formation | 2.18 | |
| 1.78 | | |||
| Hel308 | HY | Hypothalamus | 0.67 | |
| 0.67 | | |||
| Hel308 | LSX | Lateral septal complex | 0.07 | |
| 0.03 | | |||
| Hel308 | MB | Midbrain | 1.59 | |
| 1.53 | | |||
| Hel308 | MY | Medulla | 4.77 | |
| 4.94 | | |||
| Hel308 | OLF | Olfactory bulb | 4.41 | |
| 2.74 | | |||
| Hel308 | P | Pons | 3.96 | |
| 3.78 | | |||
| Hel308 | PAL | Pallidum | 0.69 | |
| 0.48 | | |||
| Hel308 | RHP | Retrohippocampal region | 0.86 | |
| 0.67 | | |||
| Hel308 | sAMY | Striatum-like amygdalar nuclei | 0.13 | |
| 0.2 | | |||
| Hel308 | STR | Striatum | 0.69 | |
| 0.68 | | |||
| Hel308 | STRd | Striatum dorsal region | 0.8 | |
| 0.78 | | |||
| Hel308 | STRv | Striatum ventral region | 0.96 | |
| 0.92 | | |||
| Hel308 | TH | Thalamus | 2.98 | |
| 2.11 | |