AutismKB 2.0

Annotation Detail for MFSD3


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Basic Information Top
Gene Symbol:MFSD3 ( - )
Gene Full Name: major facilitator superfamily domain containing 3
Band: 8q24.3
Quick LinksEntrez ID:113655; OMIM: NA; Uniprot ID:MFSD3_HUMAN; ENSEMBL ID: ENSG00000167700; HGNC ID: 25157
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal62 / 336030718
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone2 / 7165527
bone marrow3 / 4880161
brain25 / 110098922
cervix9 / 48171186
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye5 / 21105423
heart4 / 8962644
intestine4 / 23447217
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph2 / 4427045
lymph node2 / 9161021
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta9 / 28082532
prostate1 / 1893455
salivary gland1 / 2015549
skin10 / 21057447
spleen1 / 5395218
stomach1 / 9661910
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_117_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.21 ± 0.59
Basal Forebrain6.46 ± 0.24
Basal Part of Pons7 ± 0.39
Cerebellar Cortex6.79 ± 0.36
Cerebellar Nuclei6.45 ± 0.48
Claustrum6.29 ± 0.52
Epithalamus6.78 ± 0.34
Frontal Lobe6.79 ± 0.38
Globus Pallidus5.73 ± 0.15
Hypothalamus6.73 ± 0.5
Insula6.76 ± 0.26
Limbic Lobe6.37 ± 0.52
Mesencephalon6.36 ± 0.37
Myelencephalon6.53 ± 0.5
Occipital Lobe5.96 ± 0.53
Parietal Lobe6.54 ± 0.4
Pontine Tegmentum6.36 ± 0.48
Striatum5.98 ± 0.48
Subthalamus6.49 ± 0.29
Temporal Lobe6.76 ± 0.36
Thalamus6.59 ± 0.32
White Matter5.89 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mfsd3CBCerebellum0.38
0.64
Mfsd3CTXCerebral cortex1.83
1.42
Mfsd3HIPHippocampal region0.63
0.6
Mfsd3HPFHippocampal formation0.57
0.53
Mfsd3HYHypothalamus0.88
1.1
Mfsd3LSXLateral septal complex0.52
0.47
Mfsd3MBMidbrain0.51
1.12
Mfsd3MYMedulla2.32
3.98
Mfsd3OLFOlfactory bulb2.33
2.11
Mfsd3PPons1.14
2.08
Mfsd3PALPallidum0.45
0.4
Mfsd3RHPRetrohippocampal region0.44
0.42
Mfsd3sAMYStriatum-like amygdalar nuclei0.48
0.33
Mfsd3STRStriatum0.38
0.35
Mfsd3STRdStriatum dorsal region0.36
0.4
Mfsd3STRvStriatum ventral region0.3
0.18
Mfsd3THThalamus0.33
0.36
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018