AutismKB 2.0

Annotation Detail for C1orf59


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Basic Information Top
Gene Symbol:C1orf59 ( FLJ30525,HEN1,MGC111091 )
Gene Full Name: chromosome 1 open reading frame 59
Band: 1p13.3
Quick LinksEntrez ID:113802; OMIM: 612178; Uniprot ID:CA059_HUMAN; ENSEMBL ID: ENSG00000162639; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor4 / 34366116
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor17 / 26384564
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal99 / 336030729
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor8 / 12494964
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood5 / 12347840
bone0 / 716550 
bone marrow2 / 4880140
brain38 / 110098934
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye2 / 2110549
heart0 / 896260 
intestine5 / 23447221
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph2 / 4427045
lymph node3 / 9161032
mammary gland1 / 1532716
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta1 / 2808253
prostate8 / 18934542
salivary gland0 / 201550 
skin8 / 21057437
spleen2 / 5395237
stomach3 / 9661931
testis47 / 330442142
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P309361
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.84 ± 0.26
Basal Forebrain8.9 ± 0.22
Basal Part of Pons9.13 ± 0.3
Cerebellar Cortex8.33 ± 0.22
Cerebellar Nuclei8.88 ± 0.2
Claustrum8.83 ± 0.21
Epithalamus8.15 ± 0.68
Frontal Lobe8.85 ± 0.33
Globus Pallidus8.44 ± 0.54
Hypothalamus9.32 ± 0.32
Insula9 ± 0.42
Limbic Lobe8.75 ± 0.36
Mesencephalon8.85 ± 0.35
Myelencephalon8.75 ± 0.44
Occipital Lobe8.41 ± 0.4
Parietal Lobe8.85 ± 0.36
Pontine Tegmentum8.8 ± 0.45
Striatum8.85 ± 0.48
Subthalamus9.57 ± 0.16
Temporal Lobe8.9 ± 0.29
Thalamus8.5 ± 0.31
White Matter8.41 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4921515J06RikCBCerebellum3.6
4.07
4921515J06RikCTXCerebral cortex3.23
2.38
4921515J06RikHIPHippocampal region5.38
5.43
4921515J06RikHPFHippocampal formation4.34
3.93
4921515J06RikHYHypothalamus0.6
0.49
4921515J06RikLSXLateral septal complex0.75
0.63
4921515J06RikMBMidbrain1.13
1
4921515J06RikMYMedulla1.41
1.68
4921515J06RikOLFOlfactory bulb6.73
4.69
4921515J06RikPPons1.2
1.46
4921515J06RikPALPallidum1.48
1.21
4921515J06RikRHPRetrohippocampal region2.59
1.85
4921515J06RiksAMYStriatum-like amygdalar nuclei5.74
3.53
4921515J06RikSTRStriatum1.13
0.73
4921515J06RikSTRdStriatum dorsal region0.48
0.32
4921515J06RikSTRvStriatum ventral region1.14
0.68
4921515J06RikTHThalamus4.52
3.58
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018