AutismKB 2.0

Annotation Detail for LACTB


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Basic Information Top
Gene Symbol:LACTB ( FLJ14902,G24,MRPL56 )
Gene Full Name: lactamase, beta
Band: 15q22.2
Quick LinksEntrez ID:114294; OMIM: 608440; Uniprot ID:LACTB_HUMAN; ENSEMBL ID: ENSG00000103642; HGNC ID: 16468
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor6 / 9635962
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal78 / 336030723
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood4 / 12347832
bone6 / 7165583
bone marrow0 / 488010 
brain6 / 11009895
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney6 / 21177728
larynx0 / 241450 
liver8 / 20774338
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland9 / 15327158
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta11 / 28082539
prostate4 / 18934521
salivary gland0 / 201550 
skin8 / 21057437
spleen2 / 5395237
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6060_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.84 ± 0.33
Basal Forebrain4.36 ± 0.36
Basal Part of Pons3.89 ± 0.43
Cerebellar Cortex4.17 ± 0.38
Cerebellar Nuclei4.27 ± 0.62
Claustrum4.66 ± 0.57
Epithalamus3.94 ± 0.67
Frontal Lobe4.37 ± 0.47
Globus Pallidus4.31 ± 0.65
Hypothalamus4.42 ± 0.41
Insula4.48 ± 0.28
Limbic Lobe4.68 ± 0.45
Mesencephalon4.46 ± 0.42
Myelencephalon4.42 ± 0.49
Occipital Lobe4.4 ± 0.48
Parietal Lobe4.34 ± 0.45
Pontine Tegmentum4.54 ± 0.45
Striatum5 ± 0.38
Subthalamus4.38 ± 0.76
Temporal Lobe4.42 ± 0.47
Thalamus4.35 ± 0.5
White Matter4.18 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
LactbCBCerebellum4.08
3.95
LactbCTXCerebral cortex8.82
5.72
LactbHIPHippocampal region8.98
7.99
LactbHPFHippocampal formation10.3
8.49
LactbHYHypothalamus0.49
0.39
LactbLSXLateral septal complex0.98
1.23
LactbMBMidbrain0.7
0.71
LactbMYMedulla1.9
1.81
LactbOLFOlfactory bulb9.65
7
LactbPPons1.06
1.14
LactbPALPallidum0.7
0.46
LactbRHPRetrohippocampal region13.87
10.2
LactbsAMYStriatum-like amygdalar nuclei0.59
0.38
LactbSTRStriatum2.66
1.71
LactbSTRdStriatum dorsal region3.42
2.1
LactbSTRvStriatum ventral region2.08
1.24
LactbTHThalamus0.86
0.54
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LACTB_HUMAN_350 22 350 371 IFHDLDMLTTVQEENEPVIYNR PRIDE
LACTB_HUMAN_410 15 410 424 FGNAMLYGYQVGLFK PRIDE
PAp00133241 31 481 511 HYASHTGGAVGASSVLLVLPEELDTETINNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018