AutismKB 2.0

Annotation Detail for CHRND


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Basic Information Top
Gene Symbol:CHRND ( ACHRD,CMS2A,FCCMS,SCCMS )
Gene Full Name: cholinergic receptor, nicotinic, delta
Band: 2q37.1
Quick LinksEntrez ID:1144; OMIM: 100720; Uniprot ID:ACHD_HUMAN; ENSEMBL ID: ENSG00000135902; HGNC ID: 1965
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal15 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart7 / 8962678
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207024_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.05
Adipocyte6.1
AdrenalCortex6.4
Adrenalgland5.15
Amygdala6.4
Appendix6.1
AtrioventricularNode4.65
BDCA4+_DentriticCells6.4
Bonemarrow6.5
BronchialEpithelialCells5.95
CD105+_Endothelial5.95
CD14+_Monocytes5.9
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7.75
CD34+7.6
CD4+_Tcells6.1
CD56+_NKCells6.35
CD71+_EarlyErythroid5.6
CD8+_Tcells5.4
CardiacMyocytes7.15
Caudatenucleus6.5
Cerebellum8.3
CerebellumPeduncles7.15
CiliaryGanglion4.3
CingulateCortex6.9
Colorectaladenocarcinoma6.2
DorsalRootGanglion3.7
FetalThyroid6.35
Fetalbrain6.85
Fetalliver10.15
Fetallung5
GlobusPallidus4.55
Heart11.05
Hypothalamus6.65
Kidney8.2
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.4
Leukemialymphoblastic(MOLT-4)7.9
Liver8.75
Lung7.3
Lymphnode5.45
Lymphoma_burkitts(Daudi)7.95
Lymphoma_burkitts(Raji)8.65
MedullaOblongata6.15
OccipitalLobe6.15
OlfactoryBulb4.7
Ovary4
Pancreas5.75
PancreaticIslet6.4
ParietalLobe8.3
Pituitary8.95
Placenta6.3
Pons7.05
PrefrontalCortex7.55
Prostate8.4
Salivarygland4.95
SkeletalMuscle9.1
Skin5.7
SmoothMuscle6.75
Spinalcord7.15
SubthalamicNucleus5.4
SuperiorCervicalGanglion6.9
TemporalLobe5.6
Testis8.5
TestisGermCell5.05
TestisIntersitial5.75
TestisLeydigCell6.3
TestisSeminiferousTubule5.25
Thalamus6.9
Thymus4.8
Thyroid7.6
Tongue6.2
Tonsil6
Trachea6.65
TrigeminalGanglion8.15
Uterus5.4
UterusCorpus5.45
WholeBlood6.55
Wholebrain5.4
colon6.05
pineal_day7.3
pineal_night7.16
retina7.825
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12918_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.6 ± 1.16
Basal Forebrain2.22 ± 0.71
Basal Part of Pons2.05 ± 0.82
Cerebellar Cortex2.12 ± 1.02
Cerebellar Nuclei2.72 ± 0.87
Claustrum3.29 ± 0.91
Epithalamus2.09 ± 1.09
Frontal Lobe2.05 ± 0.95
Globus Pallidus2.8 ± 0.78
Hypothalamus2.13 ± 0.78
Insula1.76 ± 0.78
Limbic Lobe2.23 ± 1.01
Mesencephalon2.41 ± 0.9
Myelencephalon2.25 ± 0.93
Occipital Lobe2.45 ± 1.15
Parietal Lobe2.22 ± 1.03
Pontine Tegmentum2.34 ± 1.03
Striatum2.42 ± 0.96
Subthalamus2.66 ± 0.59
Temporal Lobe2.18 ± 1.01
Thalamus2.15 ± 0.76
White Matter2.33 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ChrndCBCerebellum28.85
46.19
ChrndCTXCerebral cortex45.75
43.43
ChrndHIPHippocampal region18.61
24.38
ChrndHPFHippocampal formation26.91
29.69
ChrndHYHypothalamus5.41
4.23
ChrndLSXLateral septal complex2.19
1.43
ChrndMBMidbrain7.3
6.71
ChrndMYMedulla10.16
9.65
ChrndOLFOlfactory bulb34.25
36.1
ChrndPPons7.78
7.47
ChrndPALPallidum7.62
7.96
ChrndRHPRetrohippocampal region38.15
35.27
ChrndsAMYStriatum-like amygdalar nuclei11.36
9.28
ChrndSTRStriatum21.29
17.42
ChrndSTRdStriatum dorsal region26.23
21.57
ChrndSTRvStriatum ventral region15.66
13.39
ChrndTHThalamus10.67
8.89
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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