AutismKB 2.0

Annotation Detail for MAL2


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Basic Information Top
Gene Symbol:MAL2 ( - )
Gene Full Name: mal, T-cell differentiation protein 2
Band: 8q24.12
Quick LinksEntrez ID:114569; OMIM: 609684; Uniprot ID:MAL2_HUMAN; ENSEMBL ID: ENSG00000147676; HGNC ID: 13634
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus28 / 56401249
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult219 / 1939121112
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13749_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.11 ± 0.72
Basal Forebrain6.35 ± 0.51
Basal Part of Pons6.66 ± 0.59
Cerebellar Cortex7.44 ± 0.25
Cerebellar Nuclei5.55 ± 0.52
Claustrum6.82 ± 0.47
Epithalamus6.35 ± 0.93
Frontal Lobe7.34 ± 0.57
Globus Pallidus4.63 ± 0.54
Hypothalamus6.49 ± 0.52
Insula7.23 ± 0.49
Limbic Lobe7.5 ± 0.82
Mesencephalon6.78 ± 0.81
Myelencephalon7.09 ± 0.63
Occipital Lobe6.92 ± 0.85
Parietal Lobe7.52 ± 0.56
Pontine Tegmentum7.01 ± 0.77
Striatum6.19 ± 0.88
Subthalamus6.52 ± 0.49
Temporal Lobe7.52 ± 0.5
Thalamus7.62 ± 0.68
White Matter4.6 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mal2CBCerebellum18.15
19.16
Mal2CTXCerebral cortex100
100
Mal2HIPHippocampal region58.69
100
Mal2HPFHippocampal formation72.74
100
Mal2HYHypothalamus10.28
8.71
Mal2LSXLateral septal complex14.97
12.75
Mal2MBMidbrain11.67
12.2
Mal2MYMedulla14.62
15.23
Mal2OLFOlfactory bulb76.27
87.02
Mal2PPons12.98
12.42
Mal2PALPallidum13.09
11.31
Mal2RHPRetrohippocampal region89.71
100
Mal2sAMYStriatum-like amygdalar nuclei15.05
12.41
Mal2STRStriatum24.43
19.34
Mal2STRdStriatum dorsal region30.31
24.13
Mal2STRvStriatum ventral region14.93
11.31
Mal2THThalamus20.83
20.47
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018