AutismKB 2.0

Annotation Detail for CYGB


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Basic Information Top
Gene Symbol:CYGB ( HGB,STAP )
Gene Full Name: cytoglobin
Band: 17q25.1
Quick LinksEntrez ID:114757; OMIM: 608759; Uniprot ID:CYGB_HUMAN; ENSEMBL ID: ENSG00000161544; HGNC ID: 16505
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor6 / 26384522
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal64 / 336030719
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS23 / 125680183
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart6 / 8962666
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve3 / 15768190
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta6 / 28082521
prostate2 / 18934510
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach2 / 9661920
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9012_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.27 ± 0.71
Basal Forebrain3.08 ± 0.59
Basal Part of Pons2.93 ± 0.66
Cerebellar Cortex3.08 ± 0.64
Cerebellar Nuclei3.56 ± 0.55
Claustrum3.49 ± 0.7
Epithalamus2.65 ± 0.54
Frontal Lobe2.7 ± 0.77
Globus Pallidus3.19 ± 0.47
Hypothalamus2.56 ± 0.62
Insula2.56 ± 0.53
Limbic Lobe2.82 ± 0.71
Mesencephalon3 ± 0.7
Myelencephalon2.91 ± 0.79
Occipital Lobe2.76 ± 0.79
Parietal Lobe2.91 ± 0.8
Pontine Tegmentum2.75 ± 0.82
Striatum3.25 ± 1.01
Subthalamus2.9 ± 0.79
Temporal Lobe2.79 ± 0.64
Thalamus2.71 ± 0.87
White Matter2.66 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CygbCBCerebellum69.5
100
CygbCTXCerebral cortex73.72
74.04
CygbHIPHippocampal region92.74
100
CygbHPFHippocampal formation85.99
100
CygbHYHypothalamus95.72
100
CygbLSXLateral septal complex42.27
38.62
CygbMBMidbrain100
100
CygbMYMedulla100
100
CygbOLFOlfactory bulb81.41
95.02
CygbPPons100
100
CygbPALPallidum79.65
100
CygbRHPRetrohippocampal region76.02
93.37
CygbsAMYStriatum-like amygdalar nuclei91.48
100
CygbSTRStriatum43.98
49.65
CygbSTRdStriatum dorsal region32.57
37.85
CygbSTRvStriatum ventral region52.94
55.75
CygbTHThalamus42.24
65.3
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018