AutismKB 2.0

Annotation Detail for GPRIN1


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Basic Information Top
Gene Symbol:GPRIN1 ( GRIN1,KIAA1893 )
Gene Full Name: G protein regulated inducer of neurite outgrowth 1
Band: 5q35.2
Quick LinksEntrez ID:114787; OMIM: 611239; Uniprot ID:GRIN1_HUMAN; ENSEMBL ID: ENSG00000169258; HGNC ID: 24835
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult10 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor7 / 26384526
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS26 / 125680206
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain52 / 110098947
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine3 / 23447212
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary2 / 10205119
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P160466
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.05 ± 0.68
Basal Forebrain7.12 ± 0.48
Basal Part of Pons7.98 ± 0.27
Cerebellar Cortex7.85 ± 0.22
Cerebellar Nuclei6.07 ± 0.78
Claustrum7.58 ± 0.48
Epithalamus6.54 ± 0.73
Frontal Lobe7.48 ± 0.64
Globus Pallidus5.13 ± 0.89
Hypothalamus7.56 ± 1.05
Insula7.83 ± 0.26
Limbic Lobe7.77 ± 0.56
Mesencephalon6.92 ± 0.8
Myelencephalon7.12 ± 0.97
Occipital Lobe6.67 ± 0.81
Parietal Lobe7.23 ± 0.51
Pontine Tegmentum7.12 ± 0.8
Striatum5.52 ± 1.02
Subthalamus6.38 ± 0.48
Temporal Lobe7.74 ± 0.46
Thalamus6.66 ± 0.57
White Matter4.92 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gprin1CBCerebellum48.49
53.52
Gprin1CTXCerebral cortex100
100
Gprin1HIPHippocampal region100
100
Gprin1HPFHippocampal formation100
100
Gprin1HYHypothalamus46.67
27.45
Gprin1LSXLateral septal complex48.5
27.4
Gprin1MBMidbrain29.5
20.78
Gprin1MYMedulla24.37
18.97
Gprin1OLFOlfactory bulb100
100
Gprin1PPons27.39
19.54
Gprin1PALPallidum46.7
32.95
Gprin1RHPRetrohippocampal region100
100
Gprin1sAMYStriatum-like amygdalar nuclei99.54
88.18
Gprin1STRStriatum31.35
22.61
Gprin1STRdStriatum dorsal region14.91
11.77
Gprin1STRvStriatum ventral region34.43
20.53
Gprin1THThalamus28.83
24.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018