AutismKB 2.0

Annotation Detail for RNF157


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Basic Information Top
Gene Symbol:RNF157 ( - )
Gene Full Name: ring finger protein 157
Band: 17q25.1
Quick LinksEntrez ID:114804; OMIM: NA; Uniprot ID:RN157_HUMAN; ENSEMBL ID: ENSG00000141576; HGNC ID: 29402
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus11 / 56401219
neonate0 / 310970 
infant7 / 23620296
juvenile0 / 555560 
adult52 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor7 / 26384526
glioma5 / 10688346
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal118 / 336030735
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma13 / 46356280
skin tumor13 / 124949104
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow0 / 488010 
brain51 / 110098946
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye29 / 211054137
heart1 / 8962611
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary0 / 1020510 
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin13 / 21057461
spleen0 / 539520 
stomach0 / 966190 
testis19 / 33044257
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P383459
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.73 ± 0.6
Basal Forebrain5.46 ± 0.36
Basal Part of Pons6.51 ± 0.25
Cerebellar Cortex5.38 ± 0.44
Cerebellar Nuclei6.11 ± 0.48
Claustrum6.23 ± 0.89
Epithalamus4.69 ± 0.73
Frontal Lobe6 ± 0.59
Globus Pallidus5.54 ± 0.6
Hypothalamus5.2 ± 0.55
Insula5.52 ± 0.52
Limbic Lobe6.11 ± 0.57
Mesencephalon5.86 ± 0.56
Myelencephalon5.84 ± 0.65
Occipital Lobe6.41 ± 0.49
Parietal Lobe6.27 ± 0.38
Pontine Tegmentum5.9 ± 0.7
Striatum5.88 ± 0.56
Subthalamus5.94 ± 0.28
Temporal Lobe5.82 ± 0.61
Thalamus6.17 ± 0.32
White Matter4.94 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rnf157CBCerebellum53.47
99.78
Rnf157CTXCerebral cortex100
100
Rnf157HIPHippocampal region76.54
100
Rnf157HPFHippocampal formation86.5
100
Rnf157HYHypothalamus23.93
26.06
Rnf157LSXLateral septal complex28.6
29.13
Rnf157MBMidbrain54.92
67.78
Rnf157MYMedulla78.55
100
Rnf157OLFOlfactory bulb91.95
100
Rnf157PPons53.81
81.12
Rnf157PALPallidum41.1
52.61
Rnf157RHPRetrohippocampal region100
100
Rnf157sAMYStriatum-like amygdalar nuclei61.45
61.12
Rnf157STRStriatum40.13
38.88
Rnf157STRdStriatum dorsal region41.34
40.43
Rnf157STRvStriatum ventral region25.35
22.92
Rnf157THThalamus31.18
36.63
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018