AutismKB 2.0

Annotation Detail for OSBPL6


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Basic Information Top
Gene Symbol:OSBPL6 ( FLJ36583,MGC59642,ORP6 )
Gene Full Name: oxysterol binding protein-like 6
Band: 2q31.2
Quick LinksEntrez ID:114880; OMIM: 606734; Uniprot ID:OSBL6_HUMAN; ENSEMBL ID: ENSG00000079156; HGNC ID: 16388
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor11 / 26384541
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal61 / 336030718
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain40 / 110098936
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx1 / 2414541
liver0 / 2077430 
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1956_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.7 ± 0.23
Basal Forebrain7 ± 0.16
Basal Part of Pons7.75 ± 0.33
Cerebellar Cortex7.27 ± 0.25
Cerebellar Nuclei7.79 ± 0.45
Claustrum7.67 ± 0.52
Epithalamus7.49 ± 0.53
Frontal Lobe7.51 ± 0.36
Globus Pallidus7.62 ± 0.31
Hypothalamus7.06 ± 0.5
Insula7.36 ± 0.41
Limbic Lobe7.68 ± 0.35
Mesencephalon7.55 ± 0.5
Myelencephalon7.53 ± 0.4
Occipital Lobe8.12 ± 0.4
Parietal Lobe7.8 ± 0.33
Pontine Tegmentum7.63 ± 0.39
Striatum7.51 ± 0.37
Subthalamus7.45 ± 0.09
Temporal Lobe7.51 ± 0.46
Thalamus7.6 ± 0.36
White Matter5.8 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Osbpl6CBCerebellum33.92
63.44
Osbpl6CTXCerebral cortex42.57
35.01
Osbpl6HIPHippocampal region49.65
83.88
Osbpl6HPFHippocampal formation54.18
71.94
Osbpl6HYHypothalamus26.94
23.17
Osbpl6LSXLateral septal complex29.74
20.79
Osbpl6MBMidbrain30.57
32.36
Osbpl6MYMedulla38.44
60.39
Osbpl6OLFOlfactory bulb37.82
30.68
Osbpl6PPons41.96
56.29
Osbpl6PALPallidum22.64
22.19
Osbpl6RHPRetrohippocampal region63.33
60.67
Osbpl6sAMYStriatum-like amygdalar nuclei24.21
19.13
Osbpl6STRStriatum12.03
10.06
Osbpl6STRdStriatum dorsal region7.78
7.4
Osbpl6STRvStriatum ventral region13.39
10.15
Osbpl6THThalamus39.02
36.75
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018