AutismKB 2.0

Annotation Detail for PTPMT1


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Basic Information Top
Gene Symbol:PTPMT1 ( DUSP23,FLJ46081,MOSP,PLIP )
Gene Full Name: protein tyrosine phosphatase, mitochondrial 1
Band: 11p11.2
Quick LinksEntrez ID:114971; OMIM: 609538; Uniprot ID:PTPM1_HUMAN; ENSEMBL ID: ENSG00000110536; HGNC ID: 26965
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult68 / 193912135
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus5 / 5640128
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal92 / 336030727
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal47 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow1 / 4880120
brain33 / 110098929
cervix3 / 4817162
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine7 / 23447229
kidney9 / 21177742
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node1 / 9161010
mammary gland5 / 15327132
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary5 / 10205148
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate11 / 18934558
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis17 / 33044251
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain12 / 110098910
cervix2 / 4817141
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye5 / 21105423
heart0 / 896260 
intestine1 / 2344724
kidney5 / 21177723
larynx0 / 241450 
liver6 / 20774328
lung2 / 3369745
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis11 / 33044233
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P372562
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.13 ± 0.16
Basal Forebrain9.24 ± 0.09
Basal Part of Pons8.91 ± 0.15
Cerebellar Cortex9.15 ± 0.17
Cerebellar Nuclei9.28 ± 0.3
Claustrum9.11 ± 0.33
Epithalamus9.68 ± 0.2
Frontal Lobe9.16 ± 0.23
Globus Pallidus9.81 ± 0.14
Hypothalamus9.47 ± 0.18
Insula9.13 ± 0.22
Limbic Lobe8.97 ± 0.22
Mesencephalon9.29 ± 0.22
Myelencephalon9.2 ± 0.24
Occipital Lobe9.26 ± 0.21
Parietal Lobe9.28 ± 0.25
Pontine Tegmentum9.3 ± 0.21
Striatum9.3 ± 0.2
Subthalamus9.29 ± 0.1
Temporal Lobe9.12 ± 0.25
Thalamus9.29 ± 0.17
White Matter9.09 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ptpmt1CBCerebellum1.7
3.02
Ptpmt1CTXCerebral cortex1.4
1.99
Ptpmt1HIPHippocampal region0.94
1.46
Ptpmt1HPFHippocampal formation0.77
1.25
Ptpmt1HYHypothalamus0.08
0.08
Ptpmt1LSXLateral septal complex0.32
0.57
Ptpmt1MBMidbrain0.52
1.04
Ptpmt1MYMedulla6.19
8.64
Ptpmt1OLFOlfactory bulb0.43
0.64
Ptpmt1PPons0.41
0.75
Ptpmt1PALPallidum0.22
0.33
Ptpmt1RHPRetrohippocampal region0.54
1.02
Ptpmt1sAMYStriatum-like amygdalar nuclei0.47
1.23
Ptpmt1STRStriatum1.26
1.58
Ptpmt1STRdStriatum dorsal region1.69
2.18
Ptpmt1STRvStriatum ventral region0.53
0.31
Ptpmt1THThalamus4.44
6.22
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00495937 13 41 53 IDPTVLLGALPLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018