AutismKB 2.0

Annotation Detail for FLYWCH2


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Basic Information Top
Gene Symbol:FLYWCH2 ( - )
Gene Full Name: FLYWCH family member 2
Band: 16p13.3
Quick LinksEntrez ID:114984; OMIM: NA; Uniprot ID:FWCH2_HUMAN; ENSEMBL ID: ENSG00000162076; HGNC ID: 25178
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma6 / 10688356
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal46 / 336030713
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain13 / 110098911
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye5 / 21105423
heart3 / 8962633
intestine3 / 23447212
kidney4 / 21177718
larynx2 / 2414582
liver1 / 2077434
lung12 / 33697435
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary7 / 10205168
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta6 / 28082521
prostate5 / 18934526
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach3 / 9661931
testis6 / 33044218
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P417596
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.18 ± 0.9
Basal Forebrain2.74 ± 0.52
Basal Part of Pons2.97 ± 0.6
Cerebellar Cortex3.31 ± 0.6
Cerebellar Nuclei3.15 ± 0.43
Claustrum3.3 ± 1.04
Epithalamus2.56 ± 0.94
Frontal Lobe2.98 ± 0.88
Globus Pallidus2.88 ± 1.11
Hypothalamus3.28 ± 0.87
Insula2.99 ± 0.86
Limbic Lobe3.06 ± 0.81
Mesencephalon3.05 ± 0.85
Myelencephalon2.96 ± 0.77
Occipital Lobe3.02 ± 0.85
Parietal Lobe3.04 ± 0.86
Pontine Tegmentum3.08 ± 0.61
Striatum2.8 ± 0.9
Subthalamus3.28 ± 0.47
Temporal Lobe2.83 ± 0.8
Thalamus3.05 ± 0.74
White Matter2.6 ± 0.95
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2810417J12RikCBCerebellum24.21
31.81
2810417J12RikCTXCerebral cortex45.66
33.68
2810417J12RikHIPHippocampal region38.26
39.25
2810417J12RikHPFHippocampal formation42.17
38.71
2810417J12RikHYHypothalamus49.36
38.47
2810417J12RikLSXLateral septal complex16.56
10.72
2810417J12RikMBMidbrain39.45
33.42
2810417J12RikMYMedulla58.48
65.85
2810417J12RikOLFOlfactory bulb55.14
47.19
2810417J12RikPPons55.01
59.62
2810417J12RikPALPallidum38.38
36.91
2810417J12RikRHPRetrohippocampal region52.92
40.97
2810417J12RiksAMYStriatum-like amygdalar nuclei54.31
40.01
2810417J12RikSTRStriatum28.54
20.69
2810417J12RikSTRdStriatum dorsal region22.09
15.46
2810417J12RikSTRvStriatum ventral region43.18
32.18
2810417J12RikTHThalamus56.14
46.82
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011205 34 105 138 QDPGTDRTEDSGLAAGPPEAAGENFAPCSVAPGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018