AutismKB 2.0

Annotation Detail for ADCY9


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Basic Information Top
Gene Symbol:ADCY9 ( AC9,FLJ12046 )
Gene Full Name: adenylate cyclase 9
Band: 16p13.3
Quick LinksEntrez ID:115; OMIM: 603302; Uniprot ID:ADCY9_HUMAN; ENSEMBL ID: ENSG00000162104; HGNC ID: 240
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus25 / 56401244
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma4 / 10688337
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal65 / 336030719
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain11 / 11009899
cervix0 / 481710 
connective tissue2 / 14925513
ear1 / 1621261
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye6 / 21105428
heart0 / 896260 
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth1 / 6705214
muscle2 / 10771518
nerve2 / 15768126
ovary4 / 10205139
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate2 / 18934510
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204497_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.1
Adipocyte8.7
AdrenalCortex8.65
Adrenalgland7.6
Amygdala20.35
Appendix7.7
AtrioventricularNode6.25
BDCA4+_DentriticCells7
Bonemarrow7.7
BronchialEpithelialCells9.95
CD105+_Endothelial7.2
CD14+_Monocytes12.35
CD19+_BCells(neg._sel.)7.15
CD33+_Myeloid24.5
CD34+9.15
CD4+_Tcells11.4
CD56+_NKCells22.85
CD71+_EarlyErythroid6.1
CD8+_Tcells16.05
CardiacMyocytes9.75
Caudatenucleus25.95
Cerebellum23.35
CerebellumPeduncles11.7
CiliaryGanglion7.3
CingulateCortex13.25
Colorectaladenocarcinoma8.5
DorsalRootGanglion6.3
FetalThyroid98.65
Fetalbrain13.35
Fetalliver11.4
Fetallung14.1
GlobusPallidus5.85
Heart23.25
Hypothalamus10.15
Kidney47.7
Leukemia_chronicMyelogenousK-5627.5
Leukemia_promyelocytic-HL-606.45
Leukemialymphoblastic(MOLT-4)5.45
Liver70.05
Lung328.6
Lymphnode6.35
Lymphoma_burkitts(Daudi)8.6
Lymphoma_burkitts(Raji)9.8
MedullaOblongata9.6
OccipitalLobe7.85
OlfactoryBulb9.15
Ovary4.75
Pancreas8.45
PancreaticIslet8.25
ParietalLobe9.75
Pituitary9.9
Placenta32.25
Pons8.4
PrefrontalCortex58.8
Prostate14.45
Salivarygland10.65
SkeletalMuscle10.5
Skin6.05
SmoothMuscle10.2
Spinalcord7.8
SubthalamicNucleus8.55
SuperiorCervicalGanglion9.25
TemporalLobe9.8
Testis32.15
TestisGermCell15.2
TestisIntersitial7.15
TestisLeydigCell7.65
TestisSeminiferousTubule7.3
Thalamus8.2
Thymus6.95
Thyroid175.15
Tongue7.85
Tonsil6.55
Trachea9.3
TrigeminalGanglion8
Uterus17.4
UterusCorpus6.5
WholeBlood8.55
Wholebrain34.3
colon25.05
pineal_day19.28
pineal_night47.28
retina62
small_intestine49.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P935103
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.14 ± 0.43
Basal Forebrain7.87 ± 0.19
Basal Part of Pons8.68 ± 0.22
Cerebellar Cortex8.14 ± 0.16
Cerebellar Nuclei8.58 ± 0.49
Claustrum8 ± 0.24
Epithalamus7.71 ± 0.23
Frontal Lobe8.19 ± 0.43
Globus Pallidus7.43 ± 0.39
Hypothalamus7.59 ± 0.4
Insula8.11 ± 0.36
Limbic Lobe8.4 ± 0.49
Mesencephalon8.1 ± 0.48
Myelencephalon8.14 ± 0.46
Occipital Lobe8.72 ± 0.34
Parietal Lobe8.44 ± 0.34
Pontine Tegmentum8.29 ± 0.44
Striatum8.93 ± 0.34
Subthalamus8.8 ± 0.38
Temporal Lobe8.16 ± 0.34
Thalamus7.98 ± 0.32
White Matter6.56 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adcy9CBCerebellum8
7.78
Adcy9CTXCerebral cortex48.56
33.6
Adcy9HIPHippocampal region68.73
91.94
Adcy9HPFHippocampal formation59.45
65.92
Adcy9HYHypothalamus3.17
2.27
Adcy9LSXLateral septal complex4.37
3.73
Adcy9MBMidbrain8.78
8.07
Adcy9MYMedulla18.2
19.33
Adcy9OLFOlfactory bulb28.37
20.83
Adcy9PPons18.04
18.77
Adcy9PALPallidum4.89
3.8
Adcy9RHPRetrohippocampal region44.73
32.35
Adcy9sAMYStriatum-like amygdalar nuclei7.6
4.96
Adcy9STRStriatum8.28
4.95
Adcy9STRdStriatum dorsal region8.45
5.08
Adcy9STRvStriatum ventral region10.13
5.3
Adcy9THThalamus5.23
4.64
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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