Annotation Detail for DDIT4L
Basic Information Top
| Gene Symbol: | DDIT4L ( REDD2,Rtp801L ) |
|---|---|
| Gene Full Name: | DNA-damage-inducible transcript 4-like |
| Band: | 4q24 |
| Quick Links | Entrez ID:115265; OMIM: 607730; Uniprot ID:DDT4L_HUMAN; ENSEMBL ID: ENSG00000145358; HGNC ID: 30555 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.480378
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 0 / 564012 | 0 | |
| neonate | 4 / 31097 | 128 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 13 / 1939121 | 6 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 3 / 12794 | 234 |  |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 81 / 3360307 | 24 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 19 / 125191 | 151 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 3 / 33197 | 90 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 2 / 123478 | 16 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 14 / 1100989 | 12 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 3 / 215722 | 13 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 1 / 211054 | 4 | |
| heart | 12 / 89626 | 133 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 7 / 336974 | 20 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 9 / 67052 | 134 | |
| muscle | 11 / 107715 | 102 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 7 / 330442 | 21 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 4 / 52413 | 76 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 23 / 232878 | 98 | |
| vascular | 2 / 51780 | 38 | |
Microarray in - Probe name: CUST_611_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.06 ± 0.75 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.52 ± 0.28 | |
| Basal Part of Pons | 4.47 ± 0.7 | |
| Cerebellar Cortex | 3.54 ± 0.48 | |
| Cerebellar Nuclei | 3.66 ± 0.69 | |
| Claustrum | 3.66 ± 0.77 | |
| Epithalamus | 5.13 ± 0.66 | |
| Frontal Lobe | 3.95 ± 0.76 | |
| Globus Pallidus | 4.49 ± 0.65 | |
| Hypothalamus | 3.77 ± 0.79 | |
| Insula | 4.12 ± 0.73 | |
| Limbic Lobe | 3.95 ± 0.78 | |
| Mesencephalon | 4.09 ± 0.71 | |
| Myelencephalon | 4.12 ± 0.92 | |
| Occipital Lobe | 4 ± 0.59 | |
| Parietal Lobe | 4.02 ± 0.7 | |
| Pontine Tegmentum | 3.74 ± 0.71 | |
| Striatum | 5.97 ± 0.57 | |
| Subthalamus | 4.37 ± 0.43 | |
| Temporal Lobe | 3.81 ± 0.58 | |
| Thalamus | 3.74 ± 0.66 | |
| White Matter | 3.08 ± 1.03 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ddit4l | CB | Cerebellum | 0.79 | |
| 1.21 | | |||
| Ddit4l | CTX | Cerebral cortex | 24.56 | |
| 28.99 | | |||
| Ddit4l | HIP | Hippocampal region | 2.26 | |
| 2.74 | | |||
| Ddit4l | HPF | Hippocampal formation | 5.32 | |
| 6.35 | | |||
| Ddit4l | HY | Hypothalamus | 0.86 | |
| 0.76 | | |||
| Ddit4l | LSX | Lateral septal complex | 2.07 | |
| 2.08 | | |||
| Ddit4l | MB | Midbrain | 1.67 | |
| 2.33 | | |||
| Ddit4l | MY | Medulla | 1.26 | |
| 1.53 | | |||
| Ddit4l | OLF | Olfactory bulb | 4.78 | |
| 4.33 | | |||
| Ddit4l | P | Pons | 0.57 | |
| 0.6 | | |||
| Ddit4l | PAL | Pallidum | 1.31 | |
| 1.19 | | |||
| Ddit4l | RHP | Retrohippocampal region | 9.17 | |
| 9.98 | | |||
| Ddit4l | sAMY | Striatum-like amygdalar nuclei | 1.92 | |
| 1.83 | | |||
| Ddit4l | STR | Striatum | 12.7 | |
| 10.06 | | |||
| Ddit4l | STRd | Striatum dorsal region | 18.74 | |
| 15.19 | | |||
| Ddit4l | STRv | Striatum ventral region | 4.35 | |
| 2.7 | | |||
| Ddit4l | TH | Thalamus | 1.43 | |
| 1.29 | |