AutismKB 2.0

Annotation Detail for CIRBP


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Basic Information Top
Gene Symbol:CIRBP ( CIRP )
Gene Full Name: cold inducible RNA binding protein
Band: 19p13.3
Quick LinksEntrez ID:1153; OMIM: 602649; Uniprot ID:CIRBP_HUMAN; ENSEMBL ID: ENSG00000099622; HGNC ID: 1982
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body28 / 70761395
blastocyst41 / 62319657
fetus148 / 564012262
neonate2 / 3109764
infant5 / 23620211
juvenile9 / 55556161
adult441 / 1939121227
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200810_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts656.55
Adipocyte136.25
AdrenalCortex383.5
Adrenalgland424.95
Amygdala623.8
Appendix136
AtrioventricularNode17.15
BDCA4+_DentriticCells1021.9
Bonemarrow79.75
BronchialEpithelialCells208.25
CD105+_Endothelial374.55
CD14+_Monocytes407.7
CD19+_BCells(neg._sel.)1446.6
CD33+_Myeloid478.35
CD34+684.75
CD4+_Tcells994.1
CD56+_NKCells1305.15
CD71+_EarlyErythroid161.45
CD8+_Tcells854.4
CardiacMyocytes204.4
Caudatenucleus311.5
Cerebellum325.9
CerebellumPeduncles839.85
CiliaryGanglion44.75
CingulateCortex364.85
Colorectaladenocarcinoma180.1
DorsalRootGanglion95.9
FetalThyroid939.75
Fetalbrain404.7
Fetalliver95.2
Fetallung431.15
GlobusPallidus198.15
Heart289.4
Hypothalamus1255.35
Kidney230.85
Leukemia_chronicMyelogenousK-562112.05
Leukemia_promyelocytic-HL-60115.7
Leukemialymphoblastic(MOLT-4)96.15
Liver59.4
Lung723.6
Lymphnode348.5
Lymphoma_burkitts(Daudi)197.95
Lymphoma_burkitts(Raji)116.2
MedullaOblongata315.95
OccipitalLobe478.05
OlfactoryBulb212.05
Ovary645.95
Pancreas350.6
PancreaticIslet1385.6
ParietalLobe470.15
Pituitary1612.4
Placenta572.6
Pons198.6
PrefrontalCortex942.4
Prostate1084.2
Salivarygland297.65
SkeletalMuscle36.6
Skin179.15
SmoothMuscle213.9
Spinalcord549.05
SubthalamicNucleus374.55
SuperiorCervicalGanglion38.8
TemporalLobe282.55
Testis510.4
TestisGermCell477.15
TestisIntersitial233.75
TestisLeydigCell193.35
TestisSeminiferousTubule257.5
Thalamus301.75
Thymus340.5
Thyroid1696.9
Tongue140.8
Tonsil236.85
Trachea260.45
TrigeminalGanglion24.85
Uterus941.9
UterusCorpus242.9
WholeBlood298.8
Wholebrain573.15
colon517.65
pineal_day1749
pineal_night1819.78
retina1316.6
small_intestine470.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13354_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.05 ± 0.45
Basal Forebrain7.97 ± 0.22
Basal Part of Pons7.64 ± 0.39
Cerebellar Cortex7.99 ± 0.27
Cerebellar Nuclei7.63 ± 0.39
Claustrum8.05 ± 0.44
Epithalamus7.78 ± 0.31
Frontal Lobe7.63 ± 0.42
Globus Pallidus8.18 ± 0.27
Hypothalamus7.83 ± 0.2
Insula7.7 ± 0.16
Limbic Lobe7.64 ± 0.39
Mesencephalon7.72 ± 0.43
Myelencephalon7.71 ± 0.34
Occipital Lobe7.54 ± 0.33
Parietal Lobe7.59 ± 0.36
Pontine Tegmentum7.64 ± 0.38
Striatum7.62 ± 0.4
Subthalamus7.06 ± 0.8
Temporal Lobe7.69 ± 0.34
Thalamus7.64 ± 0.33
White Matter9.03 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CirbpCBCerebellum27.67
38.38
CirbpCTXCerebral cortex81.45
64.46
CirbpHIPHippocampal region37.94
43.47
CirbpHPFHippocampal formation47.75
46.95
CirbpHYHypothalamus51.29
42.38
CirbpLSXLateral septal complex34.77
25.26
CirbpMBMidbrain41.32
36.44
CirbpMYMedulla26.47
26.87
CirbpOLFOlfactory bulb67.82
62.2
CirbpPPons31.92
31.84
CirbpPALPallidum49.8
45.59
CirbpRHPRetrohippocampal region62.18
50.74
CirbpsAMYStriatum-like amygdalar nuclei73.66
58
CirbpSTRStriatum29.37
22.36
CirbpSTRdStriatum dorsal region20.71
16.3
CirbpSTRvStriatum ventral region37.22
25.48
CirbpTHThalamus44.79
36.91
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CIRBP_HUMAN_162 11 162 172 DSYDSYATHNE PRIDE
CIRBP_HUMAN_62 14 62 75 DAMMAMNGKSVDGR PRIDE
PAp00068139 14 48 61 GFGFVTFENIDDAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018