AutismKB 2.0

Annotation Detail for GBP4


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Basic Information Top
Gene Symbol:GBP4 ( Mpa2 )
Gene Full Name: guanylate binding protein 4
Band: 1p22.2
Quick LinksEntrez ID:115361; OMIM: 612466; Uniprot ID:GBP4_HUMAN; ENSEMBL ID: ENSG00000162654; HGNC ID: 20480
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal37 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor20 / 90257221
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow2 / 4880140
brain3 / 11009892
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye1 / 2110544
heart1 / 8962611
intestine5 / 23447221
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta7 / 28082524
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach6 / 9661962
testis1 / 3304423
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus22 / 23287894
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P103496
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.16 ± 0.23
Basal Forebrain7.47 ± 0.35
Basal Part of Pons7.44 ± 0.24
Cerebellar Cortex7.08 ± 0.22
Cerebellar Nuclei8.31 ± 0.39
Claustrum7.7 ± 0.42
Epithalamus7.43 ± 0.58
Frontal Lobe7.56 ± 0.43
Globus Pallidus8.74 ± 0.35
Hypothalamus7.31 ± 0.49
Insula7.4 ± 0.49
Limbic Lobe7.52 ± 0.54
Mesencephalon7.83 ± 0.45
Myelencephalon7.75 ± 0.45
Occipital Lobe7.72 ± 0.51
Parietal Lobe7.51 ± 0.47
Pontine Tegmentum7.6 ± 0.57
Striatum8.41 ± 0.46
Subthalamus7.98 ± 0.1
Temporal Lobe7.4 ± 0.36
Thalamus7.86 ± 0.38
White Matter8.4 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gbp3CBCerebellum0.71
1.34
Gbp3CTXCerebral cortex3.13
2.52
Gbp3HIPHippocampal region3.97
3.44
Gbp3HPFHippocampal formation3.15
2.61
Gbp3HYHypothalamus0.23
0.25
Gbp3LSXLateral septal complex0.66
0.61
Gbp3MBMidbrain0.49
0.8
Gbp3MYMedulla0.47
0.97
Gbp3OLFOlfactory bulb1.68
1.65
Gbp3PPons0.92
2.88
Gbp3PALPallidum0.68
0.58
Gbp3RHPRetrohippocampal region1.47
1.22
Gbp3sAMYStriatum-like amygdalar nuclei2.05
1.86
Gbp3STRStriatum1.08
0.86
Gbp3STRdStriatum dorsal region0.95
0.76
Gbp3STRvStriatum ventral region1.42
0.97
Gbp3THThalamus0.8
0.79
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GBP4_HUMAN_511 11 511 521 EAAEKEQELLR PRIDE
PAp00026647 18 359 376 LPTDTLQELLDVHAACER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018