AutismKB 2.0

Annotation Detail for GBP5


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Basic Information Top
Gene Symbol:GBP5 ( GBP-5 )
Gene Full Name: guanylate binding protein 5
Band: 1p22.2
Quick LinksEntrez ID:115362; OMIM: 611467; Uniprot ID:GBP5_HUMAN; ENSEMBL ID: ENSG00000154451; HGNC ID: 19895
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor7 / 26384526
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal85 / 336030725
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood37 / 123478299
bone1 / 7165513
bone marrow0 / 488010 
brain4 / 11009893
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus2 / 2020998
eye2 / 2110549
heart0 / 896260 
intestine1 / 2344724
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung13 / 33697438
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen6 / 53952111
stomach4 / 9661941
testis3 / 3304429
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P74290
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.83 ± 1.07
Basal Forebrain2.45 ± 0.63
Basal Part of Pons3.24 ± 0.53
Cerebellar Cortex2.2 ± 0.56
Cerebellar Nuclei2.69 ± 0.64
Claustrum2.79 ± 0.68
Epithalamus3.53 ± 0.76
Frontal Lobe2.45 ± 0.76
Globus Pallidus3.79 ± 0.67
Hypothalamus2.63 ± 0.81
Insula2.19 ± 0.87
Limbic Lobe2.43 ± 0.72
Mesencephalon2.62 ± 0.86
Myelencephalon2.73 ± 0.76
Occipital Lobe2.75 ± 0.86
Parietal Lobe2.54 ± 0.78
Pontine Tegmentum2.41 ± 0.82
Striatum3.13 ± 0.87
Subthalamus2.84 ± 1.18
Temporal Lobe2.62 ± 0.79
Thalamus2.71 ± 0.73
White Matter3.35 ± 1.02
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gbp5CBCerebellum2.27
3.3
Gbp5CTXCerebral cortex7.23
5.75
Gbp5HIPHippocampal region3.29
4.28
Gbp5HPFHippocampal formation3.39
3.72
Gbp5HYHypothalamus1.34
1.26
Gbp5LSXLateral septal complex0.64
0.93
Gbp5MBMidbrain1.3
1.76
Gbp5MYMedulla2.28
2.45
Gbp5OLFOlfactory bulb9.03
7.55
Gbp5PPons1.39
1.79
Gbp5PALPallidum2.11
2.02
Gbp5RHPRetrohippocampal region3.73
2.98
Gbp5sAMYStriatum-like amygdalar nuclei2.62
1.99
Gbp5STRStriatum2.62
2.2
Gbp5STRdStriatum dorsal region2.99
2.56
Gbp5STRvStriatum ventral region2.23
1.71
Gbp5THThalamus1.72
1.57
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011064 14 397 410 NLEASSDYCSALLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018