AutismKB 2.0

Annotation Detail for LRRC56


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Basic Information Top
Gene Symbol:LRRC56 ( DKFZp761L1518,FLJ00101 )
Gene Full Name: leucine rich repeat containing 56
Band: 11p15.5
Quick LinksEntrez ID:115399; OMIM: NA; Uniprot ID:LRC56_HUMAN; ENSEMBL ID: ENSG00000161328; HGNC ID: 25430
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal15 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain15 / 110098913
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9578_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.83 ± 0.99
Basal Forebrain2.77 ± 0.66
Basal Part of Pons3.35 ± 0.41
Cerebellar Cortex2.54 ± 0.55
Cerebellar Nuclei3.35 ± 0.54
Claustrum3.18 ± 0.96
Epithalamus2.14 ± 0.42
Frontal Lobe2.7 ± 0.74
Globus Pallidus3.13 ± 0.87
Hypothalamus2.36 ± 0.74
Insula2.34 ± 1.02
Limbic Lobe2.6 ± 0.71
Mesencephalon2.52 ± 0.8
Myelencephalon2.55 ± 0.67
Occipital Lobe2.47 ± 0.8
Parietal Lobe2.53 ± 0.72
Pontine Tegmentum2.65 ± 0.78
Striatum2.62 ± 0.74
Subthalamus2.51 ± 0.22
Temporal Lobe2.59 ± 0.65
Thalamus2.64 ± 0.76
White Matter1.47 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrrc56CBCerebellum7.2
11.12
Lrrc56CTXCerebral cortex27.79
22.34
Lrrc56HIPHippocampal region9.55
12
Lrrc56HPFHippocampal formation17.01
17.96
Lrrc56HYHypothalamus0.25
0.56
Lrrc56LSXLateral septal complex0.58
0.38
Lrrc56MBMidbrain2.35
3.63
Lrrc56MYMedulla1.37
1.57
Lrrc56OLFOlfactory bulb16.22
14.21
Lrrc56PPons1.14
1.62
Lrrc56PALPallidum0.48
0.51
Lrrc56RHPRetrohippocampal region29.09
26.15
Lrrc56sAMYStriatum-like amygdalar nuclei1.37
1.05
Lrrc56STRStriatum4.05
3.01
Lrrc56STRdStriatum dorsal region5.79
4.41
Lrrc56STRvStriatum ventral region0.72
0.52
Lrrc56THThalamus1.04
0.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LRC56_HUMAN_22 15 22 36 ELSWQGLHNPCPQSK PRIDE
LRC56_HUMAN_270 6 270 275 GAPIRR PRIDE
LRC56_HUMAN_400 16 400 415 HPESQQEGAVAPWGPR PRIDE
LRC56_HUMAN_417 12 417 428 VPEEQVHQAEPK PRIDE
LRC56_HUMAN_45 14 45 58 LGEQLVEEYLSPAR PRIDE
LRC56_HUMAN_481 20 481 500 VLGSWGPGLGDGVAAVPVLR PRIDE
LRC56_HUMAN_73 9 73 81 TLEMCVDTR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018