AutismKB 2.0

Annotation Detail for ZNF689


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZNF689 ( DKFZp762C173,FLJ90415,TIPUH1 )
Gene Full Name: zinc finger protein 689
Band: 16p11.2
Quick LinksEntrez ID:115509; OMIM: NA; Uniprot ID:ZN689_HUMAN; ENSEMBL ID: ENSG00000156853; HGNC ID: 25173
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus28 / 56401249
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor11 / 26384541
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia8 / 9584283
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma43 / 71755599
non-neoplasia0 / 972500 
normal81 / 336030724
ovarian tumor7 / 7668291
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood4 / 12347832
bone2 / 7165527
bone marrow3 / 4880161
brain15 / 110098913
cervix2 / 4817141
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye5 / 21105423
heart2 / 8962622
intestine0 / 2344720 
kidney5 / 21177723
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph43 / 44270971
lymph node7 / 9161076
mammary gland4 / 15327126
mouth1 / 6705214
muscle7 / 10771564
nerve0 / 157680 
ovary8 / 10205178
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate7 / 18934536
salivary gland0 / 201550 
skin11 / 21057452
spleen0 / 539520 
stomach2 / 9661920
testis30 / 33044290
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2201_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.88 ± 0.39
Basal Forebrain6.66 ± 0.27
Basal Part of Pons6.69 ± 0.42
Cerebellar Cortex6.34 ± 0.27
Cerebellar Nuclei6.57 ± 0.31
Claustrum6.95 ± 0.45
Epithalamus6.31 ± 0.41
Frontal Lobe6.42 ± 0.36
Globus Pallidus6.96 ± 0.29
Hypothalamus6.18 ± 0.51
Insula6.38 ± 0.41
Limbic Lobe6.75 ± 0.42
Mesencephalon6.48 ± 0.42
Myelencephalon6.61 ± 0.41
Occipital Lobe6.91 ± 0.43
Parietal Lobe6.65 ± 0.42
Pontine Tegmentum6.57 ± 0.4
Striatum7.04 ± 0.45
Subthalamus6.53 ± 0.29
Temporal Lobe6.55 ± 0.34
Thalamus6.62 ± 0.35
White Matter6.92 ± 0.45
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018