AutismKB 2.0

Annotation Detail for KIR3DL3


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Basic Information Top
Gene Symbol:KIR3DL3 ( CD158Z,KIR3DL7,KIR44,KIRC1 )
Gene Full Name: killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
Band: 19q13.42
Quick LinksEntrez ID:115653; OMIM: 610095; Uniprot ID:KI3L3_HUMAN; ENSEMBL ID: ENSG00000189013; HGNC ID: 16312
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216676_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.2
Adipocyte3.35
AdrenalCortex3.5
Adrenalgland2.85
Amygdala3.6
Appendix3.5
AtrioventricularNode2.75
BDCA4+_DentriticCells3.75
Bonemarrow3.7
BronchialEpithelialCells3.35
CD105+_Endothelial3.4
CD14+_Monocytes3.6
CD19+_BCells(neg._sel.)3.5
CD33+_Myeloid4.25
CD34+4.25
CD4+_Tcells3.65
CD56+_NKCells49.85
CD71+_EarlyErythroid3.15
CD8+_Tcells3.25
CardiacMyocytes4.35
Caudatenucleus3.05
Cerebellum2.75
CerebellumPeduncles3.85
CiliaryGanglion2.45
CingulateCortex3.55
Colorectaladenocarcinoma3.4
DorsalRootGanglion2.8
FetalThyroid3.3
Fetalbrain3.4
Fetalliver3
Fetallung2.8
GlobusPallidus2.5
Heart4.45
Hypothalamus3.7
Kidney2.75
Leukemia_chronicMyelogenousK-5623.05
Leukemia_promyelocytic-HL-603
Leukemialymphoblastic(MOLT-4)2.7
Liver4.5
Lung3.7
Lymphnode2.9
Lymphoma_burkitts(Daudi)4.3
Lymphoma_burkitts(Raji)4.7
MedullaOblongata3.1
OccipitalLobe3
OlfactoryBulb2.7
Ovary2.35
Pancreas2.75
PancreaticIslet3.6
ParietalLobe3.55
Pituitary4
Placenta3.5
Pons3.25
PrefrontalCortex4.3
Prostate4
Salivarygland2.7
SkeletalMuscle3.95
Skin2.95
SmoothMuscle3.9
Spinalcord3.65
SubthalamicNucleus3.1
SuperiorCervicalGanglion4.6
TemporalLobe3.1
Testis2.9
TestisGermCell2.85
TestisIntersitial2.8
TestisLeydigCell3.35
TestisSeminiferousTubule2.9
Thalamus3.45
Thymus2.7
Thyroid4.2
Tongue3.3
Tonsil3.3
Trachea2.8
TrigeminalGanglion3.75
Uterus2.8
UterusCorpus3.05
WholeBlood3.75
Wholebrain2.85
colon3.4
pineal_day4.24
pineal_night4.14
retina4.05
small_intestine3.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16347_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 1.1
Basal Forebrain1.69 ± 0.22
Basal Part of Pons1.37 ± 0.38
Cerebellar Cortex1.54 ± 0.49
Cerebellar Nuclei2.03 ± 0.77
Claustrum2.72 ± 0.98
Epithalamus1.44 ± 0.61
Frontal Lobe1.55 ± 0.68
Globus Pallidus2.17 ± 0.39
Hypothalamus1.81 ± 0.76
Insula1.59 ± 0.53
Limbic Lobe1.78 ± 0.82
Mesencephalon1.83 ± 0.67
Myelencephalon1.74 ± 0.71
Occipital Lobe1.92 ± 1.14
Parietal Lobe1.58 ± 0.49
Pontine Tegmentum1.78 ± 0.75
Striatum2.05 ± 1.01
Subthalamus1.79 ± 0.61
Temporal Lobe1.6 ± 0.73
Thalamus1.66 ± 0.6
White Matter2.23 ± 0.37
Mouse Brain ISH
Peptide Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018