AutismKB 2.0

Annotation Detail for DHRS1


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Basic Information Top
Gene Symbol:DHRS1 ( DKFZp586I0523,FLJ14250,FLJ25430,MGC20204,SDR19C1 )
Gene Full Name: dehydrogenase/reductase (SDR family) member 1
Band: 14q12
Quick LinksEntrez ID:115817; OMIM: 610410; Uniprot ID:DHRS1_HUMAN; ENSEMBL ID: ENSG00000157379; HGNC ID: 16445
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal8 / 33603072
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213279_at
Cell line Expression level Expression bar
721_B_lymphoblasts168.65
Adipocyte64.3
AdrenalCortex103.9
Adrenalgland81.6
Amygdala59.7
Appendix115.4
AtrioventricularNode67.15
BDCA4+_DentriticCells110.55
Bonemarrow81.05
BronchialEpithelialCells373.65
CD105+_Endothelial63.05
CD14+_Monocytes99.1
CD19+_BCells(neg._sel.)102.7
CD33+_Myeloid106.8
CD34+94.7
CD4+_Tcells160.55
CD56+_NKCells137.3
CD71+_EarlyErythroid48
CD8+_Tcells142.65
CardiacMyocytes83.5
Caudatenucleus54.6
Cerebellum57.85
CerebellumPeduncles88.15
CiliaryGanglion37.3
CingulateCortex61.45
Colorectaladenocarcinoma118.7
DorsalRootGanglion44.8
FetalThyroid80.35
Fetalbrain70.65
Fetalliver148.7
Fetallung82.25
GlobusPallidus37.35
Heart128.45
Hypothalamus73.55
Kidney107.5
Leukemia_chronicMyelogenousK-56255.15
Leukemia_promyelocytic-HL-6049.9
Leukemialymphoblastic(MOLT-4)29.05
Liver1312.8
Lung142.6
Lymphnode94.15
Lymphoma_burkitts(Daudi)126
Lymphoma_burkitts(Raji)99.15
MedullaOblongata67.55
OccipitalLobe51.25
OlfactoryBulb58.95
Ovary23.8
Pancreas51.45
PancreaticIslet71.5
ParietalLobe65.15
Pituitary77.2
Placenta63.35
Pons68.55
PrefrontalCortex67.05
Prostate171.6
Salivarygland55.5
SkeletalMuscle112.75
Skin59.05
SmoothMuscle55.1
Spinalcord78.3
SubthalamicNucleus58.9
SuperiorCervicalGanglion118.55
TemporalLobe59.6
Testis94.15
TestisGermCell53.6
TestisIntersitial56.85
TestisLeydigCell79
TestisSeminiferousTubule69.6
Thalamus48.6
Thymus78.65
Thyroid221.6
Tongue313.3
Tonsil97.9
Trachea96.05
TrigeminalGanglion74.5
Uterus61.25
UterusCorpus112.55
WholeBlood67.2
Wholebrain68.3
colon143.35
pineal_day82.46
pineal_night108.9
retina86.725
small_intestine221.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P48747
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.34 ± 0.73
Basal Forebrain5.95 ± 0.26
Basal Part of Pons6.25 ± 0.39
Cerebellar Cortex6.18 ± 0.38
Cerebellar Nuclei6.06 ± 0.39
Claustrum5.07 ± 0.83
Epithalamus6.37 ± 0.56
Frontal Lobe5.91 ± 0.49
Globus Pallidus6.18 ± 0.27
Hypothalamus6.3 ± 0.53
Insula5.95 ± 0.38
Limbic Lobe5.61 ± 0.52
Mesencephalon5.89 ± 0.57
Myelencephalon5.88 ± 0.56
Occipital Lobe5.82 ± 0.47
Parietal Lobe5.75 ± 0.58
Pontine Tegmentum5.76 ± 0.44
Striatum5.72 ± 0.49
Subthalamus5.77 ± 0.48
Temporal Lobe5.96 ± 0.42
Thalamus5.99 ± 0.47
White Matter6.91 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dhrs1CBCerebellum1.01
1.77
Dhrs1CTXCerebral cortex4.07
4.22
Dhrs1HIPHippocampal region15.77
19.06
Dhrs1HPFHippocampal formation13.65
15.22
Dhrs1HYHypothalamus8.61
9.23
Dhrs1LSXLateral septal complex0.39
0.31
Dhrs1MBMidbrain2.28
4.37
Dhrs1MYMedulla1.68
3.41
Dhrs1OLFOlfactory bulb8.26
7.93
Dhrs1PPons5.05
9.9
Dhrs1PALPallidum8.68
12.65
Dhrs1RHPRetrohippocampal region8.98
8.81
Dhrs1sAMYStriatum-like amygdalar nuclei8.11
8.04
Dhrs1STRStriatum2.28
2.95
Dhrs1STRdStriatum dorsal region1.33
1.91
Dhrs1STRvStriatum ventral region2.87
4.59
Dhrs1THThalamus7.56
8.03
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009753 17 235 251 CVVALATDPNILSLSGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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