AutismKB 2.0

Annotation Detail for ADCYAP1


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Basic Information Top
Gene Symbol:ADCYAP1 ( MGC126852,PACAP )
Gene Full Name: adenylate cyclase activating polypeptide 1 (pituitary)
Band: 18p11.32
Quick LinksEntrez ID:116; OMIM: 102980; Uniprot ID:PACA_HUMAN; ENSEMBL ID: ENSG00000141433; HGNC ID: 241
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal36 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone0 / 716550 
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas32 / 214812148
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206281_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.15
Adipocyte4.15
AdrenalCortex4.3
Adrenalgland3.5
Amygdala4.5
Appendix4.25
AtrioventricularNode3.25
BDCA4+_DentriticCells4.7
Bonemarrow4.15
BronchialEpithelialCells4.15
CD105+_Endothelial4.25
CD14+_Monocytes4.5
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.4
CD34+5.35
CD4+_Tcells4.55
CD56+_NKCells5.05
CD71+_EarlyErythroid3.9
CD8+_Tcells4.05
CardiacMyocytes5.25
Caudatenucleus3.75
Cerebellum3.4
CerebellumPeduncles4.85
CiliaryGanglion3
CingulateCortex4.3
Colorectaladenocarcinoma4.2
DorsalRootGanglion3.25
FetalThyroid4.1
Fetalbrain4.2
Fetalliver3.65
Fetallung3.55
GlobusPallidus3.05
Heart5.3
Hypothalamus15
Kidney3.4
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-603.7
Leukemialymphoblastic(MOLT-4)3.35
Liver5.45
Lung4.65
Lymphnode3.65
Lymphoma_burkitts(Daudi)5.3
Lymphoma_burkitts(Raji)5.8
MedullaOblongata3.9
OccipitalLobe3.8
OlfactoryBulb3.3
Ovary2.75
Pancreas3.35
PancreaticIslet252.5
ParietalLobe4.45
Pituitary4.9
Placenta4.4
Pons4.85
PrefrontalCortex5.3
Prostate5
Salivarygland3.3
SkeletalMuscle4.85
Skin3.2
SmoothMuscle4.75
Spinalcord4.5
SubthalamicNucleus3.9
SuperiorCervicalGanglion4.75
TemporalLobe3.85
Testis3.65
TestisGermCell3.85
TestisIntersitial3.55
TestisLeydigCell4.2
TestisSeminiferousTubule3.6
Thalamus4.95
Thymus3.3
Thyroid5.3
Tongue4.1
Tonsil4.1
Trachea3.5
TrigeminalGanglion4.35
Uterus3.45
UterusCorpus3.75
WholeBlood4.55
Wholebrain8.6
colon4.25
pineal_day5.2
pineal_night5.12
retina5.075
small_intestine4.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_60_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.92 ± 0.99
Basal Forebrain5.34 ± 0.78
Basal Part of Pons8.36 ± 0.27
Cerebellar Cortex7.37 ± 0.46
Cerebellar Nuclei6.1 ± 0.99
Claustrum6.41 ± 0.86
Epithalamus6.84 ± 2.05
Frontal Lobe7.23 ± 0.92
Globus Pallidus3.9 ± 1.26
Hypothalamus7.61 ± 1.43
Insula7.51 ± 0.37
Limbic Lobe6.33 ± 1.28
Mesencephalon6.58 ± 1.69
Myelencephalon7.06 ± 1.43
Occipital Lobe6.66 ± 1.07
Parietal Lobe6.87 ± 0.93
Pontine Tegmentum6.5 ± 1.42
Striatum3.83 ± 1.65
Subthalamus7.5 ± 1.03
Temporal Lobe7.05 ± 0.82
Thalamus8.12 ± 1.06
White Matter3.67 ± 0.74
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adcyap1CBCerebellum15.93
24.76
Adcyap1CTXCerebral cortex39.45
43.19
Adcyap1HIPHippocampal region6.1
13.58
Adcyap1HPFHippocampal formation9.33
14.5
Adcyap1HYHypothalamus54.11
81.25
Adcyap1LSXLateral septal complex1.12
1.18
Adcyap1MBMidbrain31.69
39.14
Adcyap1MYMedulla22.37
32.14
Adcyap1OLFOlfactory bulb30.58
42.94
Adcyap1PPons23.12
30.71
Adcyap1PALPallidum4.5
6.51
Adcyap1RHPRetrohippocampal region14.08
15.7
Adcyap1sAMYStriatum-like amygdalar nuclei20.52
27.74
Adcyap1STRStriatum2.79
3.62
Adcyap1STRdStriatum dorsal region0.42
0.41
Adcyap1STRvStriatum ventral region1.58
2.03
Adcyap1THThalamus11.5
15.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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