AutismKB 2.0

Annotation Detail for ACSM1


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Basic Information Top
Gene Symbol:ACSM1 ( BUCS1,MACS1,MGC150532 )
Gene Full Name: acyl-CoA synthetase medium-chain family member 1
Band: 16p12.3
Quick LinksEntrez ID:116285; OMIM: NA; Uniprot ID:ACSM1_HUMAN; ENSEMBL ID: ENSG00000166743; HGNC ID: 18049
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult6 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal13 / 33603073
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215432_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.35
Adipocyte7.35
AdrenalCortex8.9
Adrenalgland6.65
Amygdala7.5
Appendix8.15
AtrioventricularNode7.25
BDCA4+_DentriticCells7.55
Bonemarrow7.75
BronchialEpithelialCells8
CD105+_Endothelial7.25
CD14+_Monocytes8
CD19+_BCells(neg._sel.)7.35
CD33+_Myeloid8.95
CD34+9.3
CD4+_Tcells7.55
CD56+_NKCells8.15
CD71+_EarlyErythroid7.1
CD8+_Tcells6.35
CardiacMyocytes10.7
Caudatenucleus6.7
Cerebellum6.1
CerebellumPeduncles9
CiliaryGanglion6.45
CingulateCortex7.95
Colorectaladenocarcinoma7.35
DorsalRootGanglion6.35
FetalThyroid7.65
Fetalbrain7.1
Fetalliver6.65
Fetallung5.45
GlobusPallidus5.8
Heart13.7
Hypothalamus7.85
Kidney6.8
Leukemia_chronicMyelogenousK-5626.75
Leukemia_promyelocytic-HL-606.6
Leukemialymphoblastic(MOLT-4)5.5
Liver10.2
Lung8
Lymphnode6.4
Lymphoma_burkitts(Daudi)10.05
Lymphoma_burkitts(Raji)11
MedullaOblongata6.8
OccipitalLobe6.65
OlfactoryBulb5.8
Ovary5.35
Pancreas6.15
PancreaticIslet7.85
ParietalLobe8.4
Pituitary8.7
Placenta7.4
Pons7.4
PrefrontalCortex8.75
Prostate8.3
Salivarygland6.4
SkeletalMuscle10.25
Skin6.55
SmoothMuscle8.35
Spinalcord7.95
SubthalamicNucleus7.1
SuperiorCervicalGanglion11.1
TemporalLobe7.05
Testis6.4
TestisGermCell8.05
TestisIntersitial6.65
TestisLeydigCell8.25
TestisSeminiferousTubule6.35
Thalamus7.7
Thymus5.75
Thyroid8.9
Tongue8.3
Tonsil7.3
Trachea6.15
TrigeminalGanglion9.85
Uterus5.8
UterusCorpus8.7
WholeBlood8.15
Wholebrain6
colon7.3
pineal_day8.94
pineal_night8.7
retina8.875
small_intestine6.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10962_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.97 ± 0.66
Basal Forebrain3.58 ± 0.35
Basal Part of Pons4.21 ± 0.59
Cerebellar Cortex4.37 ± 0.39
Cerebellar Nuclei3.9 ± 0.51
Claustrum3.8 ± 0.73
Epithalamus3.25 ± 0.4
Frontal Lobe3.72 ± 0.63
Globus Pallidus4.41 ± 0.48
Hypothalamus4.24 ± 0.68
Insula3.6 ± 0.38
Limbic Lobe3.96 ± 0.67
Mesencephalon3.94 ± 0.65
Myelencephalon3.95 ± 0.69
Occipital Lobe3.98 ± 0.64
Parietal Lobe3.92 ± 0.62
Pontine Tegmentum3.87 ± 0.59
Striatum3.65 ± 0.84
Subthalamus4.73 ± 0.46
Temporal Lobe4.01 ± 0.67
Thalamus3.71 ± 0.66
White Matter5.27 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Acsm1CBCerebellum0.05
0.26
Acsm1CTXCerebral cortex1.17
1.27
Acsm1HIPHippocampal region0.46
0.66
Acsm1HPFHippocampal formation0.4
0.64
Acsm1HYHypothalamus0.02
0.05
Acsm1LSXLateral septal complex0
0
Acsm1MBMidbrain0.08
0.29
Acsm1MYMedulla0.02
0.09
Acsm1OLFOlfactory bulb0.35
0.85
Acsm1PPons0.13
0.33
Acsm1PALPallidum0.04
0.02
Acsm1RHPRetrohippocampal region0.3
0.63
Acsm1sAMYStriatum-like amygdalar nuclei0.71
1.1
Acsm1STRStriatum0.27
0.57
Acsm1STRdStriatum dorsal region0.28
0.68
Acsm1STRvStriatum ventral region0.12
0.1
Acsm1THThalamus0.2
0.55
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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