AutismKB 2.0

Annotation Detail for LYPD1


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Basic Information Top
Gene Symbol:LYPD1 ( FLJ41033,LYPDC1,MGC29643,PHTS )
Gene Full Name: LY6/PLAUR domain containing 1
Band: 2q21.2
Quick LinksEntrez ID:116372; OMIM: 610450; Uniprot ID:LYPD1_HUMAN; ENSEMBL ID: ENSG00000150551; HGNC ID: 28431
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212909_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.2
Adipocyte4.15
AdrenalCortex4.55
Adrenalgland3.6
Amygdala4.55
Appendix4.35
AtrioventricularNode3.35
BDCA4+_DentriticCells4.45
Bonemarrow4.25
BronchialEpithelialCells4.1
CD105+_Endothelial4.25
CD14+_Monocytes4.45
CD19+_BCells(neg._sel.)4.45
CD33+_Myeloid5.35
CD34+5.3
CD4+_Tcells4.45
CD56+_NKCells5
CD71+_EarlyErythroid3.95
CD8+_Tcells4
CardiacMyocytes8.9
Caudatenucleus3.85
Cerebellum3.5
CerebellumPeduncles4.8
CiliaryGanglion3.1
CingulateCortex4.35
Colorectaladenocarcinoma4.25
DorsalRootGanglion3.3
FetalThyroid4.1
Fetalbrain4.3
Fetalliver3.7
Fetallung3.4
GlobusPallidus3.15
Heart5.6
Hypothalamus10
Kidney3.5
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)3.35
Liver5.7
Lung4.6
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.4
Lymphoma_burkitts(Raji)6.05
MedullaOblongata3.85
OccipitalLobe3.8
OlfactoryBulb3.35
Ovary2.8
Pancreas3.45
PancreaticIslet5.05
ParietalLobe4.5
Pituitary5
Placenta4.3
Pons4
PrefrontalCortex5.2
Prostate4.85
Salivarygland3.4
SkeletalMuscle5.3
Skin3.3
SmoothMuscle42.95
Spinalcord4.55
SubthalamicNucleus3.9
SuperiorCervicalGanglion4.95
TemporalLobe3.9
Testis3.6
TestisGermCell3.5
TestisIntersitial3.5
TestisLeydigCell4.2
TestisSeminiferousTubule3.6
Thalamus4.35
Thymus3.25
Thyroid5.2
Tongue4.2
Tonsil4.1
Trachea3.5
TrigeminalGanglion4.35
Uterus3.4
UterusCorpus3.8
WholeBlood4.55
Wholebrain3.65
colon4.25
pineal_day5.22
pineal_night5.12
retina5.35
small_intestine4.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P101031
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.5 ± 0.68
Basal Forebrain11.14 ± 0.27
Basal Part of Pons9.02 ± 0.32
Cerebellar Cortex9.65 ± 0.18
Cerebellar Nuclei9.78 ± 0.42
Claustrum9.35 ± 0.34
Epithalamus10.45 ± 0.46
Frontal Lobe10.11 ± 0.47
Globus Pallidus11.02 ± 0.35
Hypothalamus10.63 ± 0.63
Insula10.41 ± 0.41
Limbic Lobe10.4 ± 0.6
Mesencephalon10.36 ± 0.5
Myelencephalon10.25 ± 0.61
Occipital Lobe9.97 ± 0.45
Parietal Lobe10.08 ± 0.51
Pontine Tegmentum10.39 ± 0.34
Striatum11.29 ± 0.64
Subthalamus10.19 ± 0.46
Temporal Lobe10.08 ± 0.42
Thalamus9.88 ± 0.48
White Matter8.69 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lypd1CBCerebellum16.25
26.26
Lypd1CTXCerebral cortex48.57
59.49
Lypd1HIPHippocampal region70.78
95.44
Lypd1HPFHippocampal formation69.29
87.34
Lypd1HYHypothalamus35.06
37.53
Lypd1LSXLateral septal complex97.87
100
Lypd1MBMidbrain30.62
32.69
Lypd1MYMedulla25.81
33.75
Lypd1OLFOlfactory bulb49.43
70.23
Lypd1PPons23.95
28.18
Lypd1PALPallidum49.79
64.43
Lypd1RHPRetrohippocampal region66.49
79.64
Lypd1sAMYStriatum-like amygdalar nuclei81.3
86.07
Lypd1STRStriatum60.01
63.61
Lypd1STRdStriatum dorsal region42.72
38.69
Lypd1STRvStriatum ventral region79.65
78.94
Lypd1THThalamus20.69
23.63
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018