AutismKB 2.0

Annotation Detail for HSPA12B


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Basic Information Top
Gene Symbol:HSPA12B ( C20orf60,FLJ32150,MGC131912,dJ1009E24.2 )
Gene Full Name: heat shock 70kD protein 12B
Band: 20p13
Quick LinksEntrez ID:116835; OMIM: 610702; Uniprot ID:HS12B_HUMAN; ENSEMBL ID: ENSG00000132622; HGNC ID: 16193
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal60 / 336030717
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain9 / 11009898
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart6 / 8962666
intestine1 / 2344724
kidney9 / 21177742
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta16 / 28082556
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen6 / 53952111
stomach1 / 9661910
testis3 / 3304429
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P91334
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.49 ± 0.53
Basal Forebrain5.7 ± 0.32
Basal Part of Pons6.04 ± 0.31
Cerebellar Cortex5.52 ± 0.52
Cerebellar Nuclei6.4 ± 0.45
Claustrum5.22 ± 0.71
Epithalamus5.43 ± 0.7
Frontal Lobe6.06 ± 0.46
Globus Pallidus6.56 ± 0.23
Hypothalamus5.58 ± 0.48
Insula6 ± 0.43
Limbic Lobe5.74 ± 0.57
Mesencephalon6.05 ± 0.48
Myelencephalon6 ± 0.48
Occipital Lobe5.88 ± 0.62
Parietal Lobe5.86 ± 0.47
Pontine Tegmentum5.81 ± 0.59
Striatum6.33 ± 0.37
Subthalamus6.07 ± 0.2
Temporal Lobe5.86 ± 0.39
Thalamus6.07 ± 0.49
White Matter5.85 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hspa12bCBCerebellum26.49
37.01
Hspa12bCTXCerebral cortex28.63
22.24
Hspa12bHIPHippocampal region10.79
10.53
Hspa12bHPFHippocampal formation15.27
13.84
Hspa12bHYHypothalamus6.1
4.71
Hspa12bLSXLateral septal complex4.89
3.28
Hspa12bMBMidbrain10.68
9.75
Hspa12bMYMedulla19.4
19.42
Hspa12bOLFOlfactory bulb29.81
24.33
Hspa12bPPons8.12
8.37
Hspa12bPALPallidum10.91
9.83
Hspa12bRHPRetrohippocampal region22.58
18.29
Hspa12bsAMYStriatum-like amygdalar nuclei3.2
2.45
Hspa12bSTRStriatum12.28
9.9
Hspa12bSTRdStriatum dorsal region12.41
10.56
Hspa12bSTRvStriatum ventral region21.11
15.04
Hspa12bTHThalamus20.23
17.32
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HS12B_HUMAN_0 0 0 0 TAGPHRAGALNISLPFSFIDFYRK PRIDE
PAp01048339 13 523 535 GAVLFGQAPGVVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018